Breathing in a special gas reveals hidden lung damage in transplant patients

NCT ID NCT04941573

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study used a special MRI technique with a harmless gas called hyperpolarized xenon-129 to take detailed pictures of lung function in people who had a lung transplant. The goal was to see if this scan could detect early signs of chronic lung allograft dysfunction (CLAD), a common complication after transplant. Researchers compared transplant patients, healthy volunteers, and people with COPD to understand how the gas moves through the lungs and where problems might be.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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Contacts and locations

Locations

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

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