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This open-label study is of adults with astigmatism who have never worn contact lenses. Subjects will be fit into a one week planned-replacement contact lenses and will wear lenses for approximately 3 weeks. Subjects will return for vision and lens fit assessments and will comple…

Background: Lung problems develop in up to 20% of people after they have surgery. While under general anesthesia, people breathe slower and draw in less air. They may have difficulty returning to normal deep breathing as they recover. Some may develop life-threatening complicati…

The goal of this study is to evaluate the effectiveness of a mind-body medicine training program on parole services staff. The main questions it aims to answer are: * Will participation in the training increase resilience; empathy; the belief that one can cope with difficult sit…

The goal of this single arm study is to: 1. primary purpose: to determine the feasibility of a novel social-emotional learning curriculum when implemented in the STEM Academy program at the Visions of Science after school program; 2a. secondary purpose: to determine whether the …

This randomized controlled study examined whether a structured digital literacy training program could improve eHealth literacy, acceptance of physical activity applications, and behavioral intentions among older women. Participants aged 55 years and older with prior experience u…

The goal of this clinical trial is to investigate the role of whole food protein source compared with supplement forms in enhancing response to resistance exercise training in moderately active participants. The main question it aims to answer: Whether wholefood protein (lean re…

This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for. The investigators will investigate the role of anesthetic volume on the duration of action at highly vascular sites.

The complement system is an important component of the innate immune system. Abnormal activation, inadequate regulation and control of the complement system, as well as impaired and dysfunctional effector functions, underlie complement mediated diseases. VSA012 targeting compleme…

Phase I with a dose finding cohort, followed by expansion cohorts in pre-specified tumor types.

The purpose of this clinical trial is to evaluate the effect of rhythmic transcranial magnetic stimulation (TMS) delivered at delta (2.2 Hz) or theta (6.5 Hz) frequency on cognitive control. This study aims to explore how targeted stimulation at delta and theta frequencies modul…

This study investigates the effects of different types of self-talk on performance and stress regulation in soccer forwards. Self-talk is a psychological technique in which athletes use specific verbal cues to guide their thoughts and actions during training and competition. Two …

Cross-cultural adaptation, validity and Reliability of Berg Balance Scale in Albanian population

The purpose of this study is to compare procedural times and Radiofrequency (RF)applications required for Pulmonary vein myocardial sleeves targeted pulmonary vein ablation (PVS-PVI) , to compare the efficacy of PVS-PVI , to compare the safety of PVS-PVI and to assess other clini…

This study investigated the effects of isometric exercises applied to the quadriceps and hamstring muscles at different knee joint angles on balance, joint position sense, and functional performance in healthy individuals. Thirty participants aged 18-26 years were randomized into…

The goal of this proof-of-concept study is to learn if interleukin-6 changes the effect of glucagon in healthy volunteers. The main question it aims to answer is: Does IL-6 influence how effectively glucagon lowers the concentration of amino acids in blood? Researchers will comp…

Spinal cord injury (SCI) is a serious condition that causes physical, psychological, and social functional impairments. Paraplegia is characterized by the loss of motor and/or sensory function at the thoracic, lumbar, or sacral levels of the spinal cord, affecting the trunk, lowe…

Patients ASA1-2, 18 to 70 years old, scheduled for elective surgery with personal conset to participate, will be randomised into two groups using different induction mode. TCI effect site mode induction or TCI plasma mode induction both using the Elevelt PKPD propofol model. Stan…

This clinical study will be performed in three phases. The purpose of Phase 1 of this study is to compare the ECG data recorded using the ZywieZ3 Sensor and ZywieZ3 Adhesive ("Test Device") to the data recorded by a traditional 3-lead ECG device that uses wet Ag-AgCl adhesives i…

This quasi-experimental embedded mixed-methods study evaluated the effect of a prenatal shared decision-making (SDM) counseling session on decisional conflict and breastfeeding performance among primiparous women in Zahedan, Iran. A total of 112 pregnant women at 35-37 weeks' ges…

It focuses on the patient care pathway and the factors influencing their choice to seek consultation in the Emergency Department or Out-of-Hours Care Service for issues that fall under general medicine. In France, emergency services are increasingly overcrowded, particularly wit…