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127005 trials found · Page 5435 of 6351
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Ultrasound could replace X-Rays for feeding tube checks in ICU kids
Knowledge-focused CompletedThis study will use point of care (POC) gastric ultrasound to confirm that nasojejunal tube (NJ) feeds result in minimal to no gastric content and therefore are low risk for aspiration and should be allowed at the very least to decrease the time that enteral feeds need to be held…
Sponsor: Joseph D. Tobias • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Can cooking classes cut heart risk? new study tests community approach
Prevention OngoingBackground: The risk of heart disease among African Americans is still common despite a greater understanding of the disease and better approaches to managing it. Healthy cooking and eating patterns can help reduce the risk of heart disease. But things like access to grocery sto…
Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Prevention
Last updated Aug 09, 2026 00:00 UTC
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Dialysis Patients' thirst under the microscope: new study tracks fluid weight gain
Knowledge-focused Recruiting nowInterdialytic weight gain determines how much fluid (ultrafiltration) has to be removed during each hemodialysis session. High ultrafiltration volumes stress the organism and lead to a higher risk of death. Thirst is the main driving factor of interdialytic weight gain, and thirs…
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Rare cancer study seeks clues in blood and lab models
Knowledge-focused Recruiting nowThe EHE observational study was developed to obtain a high number of datas such as clinical presentation, natural history, and treatment outcomes, cto identificate cytokines and hormones as biomarkers and generate patient-derived preclinical models as a tool to assess the activit…
Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Nurse Check-Ins boost heart valve recovery, study finds
Symptom relief CompletedThe objective of this study is to evaluate the impact of a program of presurgical and postsurgical nurse interventions (PROCESS-VALVE) on quality indicators of the health of patients undergoing percutaneous valve procedures. (waiting times, patient satisfaction, admission times, …
Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Pandemic's hidden toll: study reveals PTSD and burnout in ICU staff
Knowledge-focused CompletedBased on the experience of previous pandemics, countries reacted by applying different upgrade strategies to prevent or delay the widespread of the disease. Therefore, measures such as border closure, school closure, restrict social gathering (even shutdown of workplaces), limit …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Real-world study tracks xolair dose bumps for stubborn hives
Knowledge-focused CompletedThis is an observational study whose main objective is to estimate the frequency of patients benefiting from an intensification of AOM treatment at 3 months.
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New eye drop offers hope for dry eye sufferers
Symptom relief CompletedThe objective of this study is to compare the safety and efficacy of 0.25% HBM9036 (HL036) Ophthalmic Solution to placebo for the treatment of the Chinese subjects with moderate and severe dry eye.
Phase 3 • Sponsor: Harbour BioMed (Guangzhou) Co. Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Can coaching doctors help veterans cut back on drinking?
Knowledge-focused CompletedIn order to improve the quality of alcohol-related care for those with unhealthy alcohol use, the current research will use an evidence-based implementation strategy, practice facilitation, at one VA primary care site to pilot test whether practice facilitation has the potential …
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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New study aims to predict end of life in lewy body dementia
Knowledge-focused CompletedThe PACE-DLB Study is for people with at least moderate dementia with Lewy bodies (DLB) and their primary caregiver. The study's goals are to learn more about the experiences of people with DLB and their caregivers as DLB progresses, and what happens as the end of life of the per…
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Tiny study could help predict rare genetic risks for developmental disorders
Knowledge-focused Completed1. Inclusion of 5 families Inclusions will be made by the clinical genetics department of the Rouen University Hospital (monocentric study) and will correspond to trios of parents + child with unexplained developmental abnormalities. The inclusion of patients will be integrated i…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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New strategy aims to help mental health staff better manage heart risks
Knowledge-focused CompletedThis pilot study will examine whether an implementation strategy will improve delivery of evidence-based care for cardiovascular risk factors for people with serious mental illness.
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Cross-Legged sitting may improve epidural success in labor
Symptom relief CompletedThe success of an epidural analgesia catheter placement depends on the parturient position. A poor posture can increase the number of punctures, patient discomfort, and risk of complications. An adequate position reverses lumbar lordosis, facilitating the access to the interverte…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Gum health may influence HIV inflammation, study finds
Knowledge-focused CompletedThis is a prospective cohort study designed to investigate the range of metabolic abnormalities observed in patients living with HIV on antiretroviral therapy. This study will also explore the concurrent role of poor oral health in supporting and driving chronic immune activation…
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Scientists track Melanoma's metabolic tricks in tiny study
Knowledge-focused Recruiting nowMelanoma in-transit metastases (ITMs) continue to represent a therapeutic dilemma, in that no standard method of treatment has been uniformly adopted. The complexity and heterogeneity of patient and disease characteristics, including the location and number of ITMs presents a bar…
Sponsor: Yana Najjar • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Mind over needle: can your thoughts boost neck pain relief?
Knowledge-focused Recruiting nowObjectives The aim of this study is to compare the effects of inducing positive expectations against negative or neutral induced expectations on the activation of the Autonomic Nervous System and the analgesic response, after a dry needling technique in upper trapezius fibers in …
Sponsor: University of Alcala • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Doctors prescribe produce: study tests if free fruits & veggies boost Kids' health
Knowledge-focused CompletedThe objective of this study is to address gaps in knowledge related to the influence of pediatric fruit and vegetable prescription programs on food security, child dietary patterns, and weight status. To do this, we will compare demographically similar pediatric patient groups fr…
Sponsor: Michigan State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Scientists uncover how PML virus hides from immune system
Knowledge-focused CompletedProgressive multifocal leukoencephalopathy (PML) is a rare viral infection of the central nervous system (CNS) occurring in immunocompromised patients. Recovery of JC virus (JCV) specific T cell immune responses is the only available therapeutic option. JCV may use immune checkpo…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Tiny fluid injection may help doctors avoid dangerous fluid overload in septic kids
Knowledge-focused CompletedSevere sepsis and septic shock remain of particular gravity in children with a current mortality of about 20 % , despite the international prevention campaigns " survival sepsis campaign ". Septic shock associates a macrocirculatory and a microcirculatory dysfunction. The volume …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Sound waves and microbubbles aim to boost heart attack clot treatment
Disease control Stopped earlyThis study will assess the safety and feasibility of sonothrombolysis in the acute management of STEMI undergoing reperfusion therapy with systemic fibrinolysis as part of a pharmacoinvasive approach
Phase 2 • Sponsor: University of Alberta • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC