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The existing literature examining the effect of female sex hormones across the phases of the menstrual cycle on muscle microdamage and oxygen uptake is limited. The protective role of estrogens against muscle microdamage is supported by findings from some studies; however, it is …

The study included two tasks to test how well people could reproduce the speed of knee movement at two different speeds (20°/s and 120°/s) under two vision conditions: eyes closed and eyes open. It included 10 participants. The equipment used was a Biodex 4 Pro dynamometer, an e…

Accurately analyzing ECG rhythms is a critical competency for nursing students. However, many students fail to achieve an adequate level of knowledge and skill in this area. Therefore, simulation-based learning approaches and innovative, interactive teaching strategies can be eff…

This study aimed to assess the prevalence of MSDs and the level of ergonomics knowledge among dentists who are specializing in different branches or have completed specialist training.

Static stretching and self-myofascial release are commonly used techniques to improve joint mobility, primarily through mechanisms such as reduced tissue stiffness, increased stretch tolerance, and warming effects. Emerging evidence suggests that these interventions may also elic…

This study is a Phase I clinical trial to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) profiles with single intravenous (IV) and intramuscular (IM) doses of ENA-001.

This study will evaluate how methotrexate is processed in the body when given with low doses of rifampicin or cyclosporine. These drugs may affect how methotrexate is absorbed and cleared, which could change its safety and effectiveness. Healthy volunteers will receive methotrexa…

This is a randomized, decentralized, non-interventional clinical study. The primary objective of this study is to develop execution and efficiency metrics from completion of this study to inform on the potential design for future projects. The secondary objective of this study is…

The main purpose of this study is to explore the safety and any side effects of LY4066708 in healthy participants. The study will also measure how much LY4066708 gets into the bloodstream and the central nervous system and how long it takes the body to remove it. The study will l…

Narcolepsy is a sleep disorder in which patients are not able to maintain wakefulness or require treatment to maintain wakefulness during the daytime. Narcolepsy is a lifelong neurologic disease for which no cure has been clinically available. JZP441 is currently being developed …

This study will examine quality of life, experiences, and unmet needs among individuals diagnosed with Low Risk Myelodysplastic Syndrome who are erythropoietin stimulating agent naïve and non-transfusion dependent and among individuals with suspected myelodysplastic syndromes wit…

A multi-site observational all-comers study that will be conducted at geographically diverse sites within the United States

Higher energy and carbohydrate intakes have been hypothesized to enhance resistance training adaptations, yet empirical evidence remains mixed. This study investigated whether supplemental carbohydrate-energy intake improves muscle hypertrophy, strength, and fatigue resistance in…

The aim of this study is to examine the effects of patients' clinical and demographic datas on cerebral oxygen saturation values. Brain oxygenation is measured using near infrared spectroscopy (NIRS). The primary outcome measure of the study is the regional oxygen saturation (rSO…

This cross-sectional study explored the impact of medical education on the health and lifestyle behaviors of undergraduate medical students at Nishtar Medical University, Multan. Medical training is known to be academically and emotionally demanding, which can significantly influ…

Purpose The purpose of this study was to determine the peak point of BDNF following exercises of different intensities. Method This randomized crossover controlled trial aimed to examine the acute effects of three experimental conditions-high-intensity interval training, long-in…

This study aims to investigate the effects of musical stimulation intensity on postural control in athletes using a virtual reality-based (VR) static posturography system. Athletes from various sports disciplines will be exposed to low-, medium-, and high-intensity music during b…

The goal of this clinical trial is to assess the safety and effects of a crystalized form of lithium, AL001, when compared to commonly used Lithium Carbonate in healthy volunteers. The main questions this study aims to answer are: How safe and effective is AL001 when compared to…

This is a single-center observational study aimed at setting up and testing new ultrasound vascular imaging protocols, conducted exclusively for research purposes. The study will perform US examinations in 60 subjects. The subjects enrolled in the study will be examined the first…

Chronic non-specific low back pain is a common health problem that significantly affects the quality of life of individuals. Increased pain intensity leads to deficiencies in the body's sensory organization, resulting in decreased awareness. This can lead to dysfunction in body a…