New study aims to uncover why some kids with high blood pressure develop heart and kidney problems

NCT ID NCT04752293

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking at children ages 7 to 18 who have been newly diagnosed with high blood pressure. Researchers want to understand how certain hormones in the body, like angiotensin-(1-7), may contribute to damage in the heart, kidneys, and blood vessels. Over two years, they will collect blood and urine samples and measure blood pressure and organ function. The goal is to learn why some children develop complications, which could lead to better treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal new targets for treating or preventing heart and kidney damage in children with high blood pressure.

What could go wrong

This is an observational study, not a treatment trial. It will not directly test any new drug or therapy. Results may take years to translate into clinical practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Albuminuria essential hypertension hypertensive disorder Hypertrophy, Left Ventricular Hyperuricemia impaired renal function disease kidney disorder left ventricular failure obesity disorder Pediatric Obesity primary dysautonomia proteinuria Ventricular Dysfunction, Left

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wake Forest Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••