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127005 trials found · Page 5213 of 6351
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New device aims to boost circulation and ward off dangerous clots
Disease control CompletedFor Deep Vein Thrombosis (DVT) risk groups, the effect and safety of blood circulation improvement before and after application are evaluated using an investigational device (model name CGM MB-1701).
Sponsor: Ceragem Clinical Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Free 3D lung maps could make surgery safer
Knowledge-focused CompletedPreoperative three-dimensional (3D) lung reconstructions can reduce intraoperative blood loss, conversion rate, and operation duration. Commercial products predominantly provide these 3D reconstructions, hence the aim of this study was to assess the usability and performance of p…
Sponsor: Erik de Loos • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Could a gentle zap to the neck ease long COVID fatigue?
Symptom relief CompletedThe purpose of this study is to evaluate the impact of vagal nerve stimulation on patients with post COVID syndrome who have fatigue and headache.
Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Sep 10, 2026 01:00 UTC
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15,000 heart attack survivors tracked for 5 years to uncover best recovery paths
Knowledge-focused Recruiting nowAMI Survivors who participated in the project "Construction and key technology research of the whole myocardial protection system for acute myocardial infarction" (project number 2016YFC1301100) and completed the 1-year visit were followed up by telephone at 3 years (within the c…
Sponsor: Yu Bo • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:33 UTC
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Can walking sooner after a broken knee speed up recovery? new study aims to find out.
Knowledge-focused By invitation onlyThe investigators aim of the study is to assess the effects of early mobilization after surgically treated unicondylar tibia plateau fractures (6 weeks without weight bearing) on gait, patient satisfaction, return to work/sports and complication rate. The data will be compared to…
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Massive biobank launches to unlock myeloma mysteries
Knowledge-focused Recruiting nowThis is an observational, non-interventional, multicenter study for the prospective collection, storage and analysis of patients' biological samples. This study establishes a common international infrastructure useful to collect standard clinical variables at baseline and during…
Sponsor: European Myeloma Network B.V. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Can a dietician and fitbit help pancreatic cancer patients feel better during chemo?
Symptom relief CompletedThe purpose of the study is to assess the feasibility and participant satisfaction with the Support through Remote Observation and Nutrition Guidance (STRONG) program. The program provides enhanced dietician access and nutrition support for participants living with pancreatic can…
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated Aug 01, 2026 00:00 UTC
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New blood test could end painful bone biopsies for kidney disease patients
Knowledge-focused Recruiting nowTreatment of renal osteodystrophy is impeded by the lack of practical and accurate tools to determine underlying bone turnover. Gold standard bone biopsy is not practical in the clinic for the vast majority of kidney disease patients and parathyroid hormone and bone alkaline phos…
Sponsor: Thomas Nickolas • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Counseling program aims to ease burnout for healthcare providers
Symptom relief CompletedThis exploratory pilot study is designed as interventional study to examine the efficacy of a wellness initiative that involves use of a licensed clinical professional counselor (LCPC) to assist in the development of diverse coping strategies such as management of stressors, self…
Sponsor: Colleen J Klein • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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New study tracks lung function and symptoms in fibrosis patients on nintedanib
Knowledge-focused Stopped earlyThe aim of this study is to identify correlations between change from the baseline at Month 24 in Forced Vital Capacity (FVC) (% predicted and mL) and change from the baseline at Month 24 in cough or dyspnoea scores \[points\] as measured in the living with pulmonary fibrosis que…
Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New study investigates whether social struggles fuel inflammation in breast cancer patients
Knowledge-focused Recruiting nowThis is a pilot trial to assess how measures of inflammation are correlated with Social Determinants of Health (SDoH) in breast cancer patients. Expected duration of subject participation is one single time point. The patients will fill out questionnaires and provide a plasma sam…
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Home workouts with video coaching tested for rare muscle disease
Symptom relief Recruiting nowPositive effect of physical activity on health arouses a strong interest at international level and is developped within the scope of national programs. Recommandations exist but must be designed for patients with functional limitations of activities. Patients with mitochondrial…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Scientists map immune defenses in ovarian cancer
Knowledge-focused Recruiting nowThis is a single center prospective observational study to characterize the immune landscape of newly diagnosed epithelial ovarian cancer (OC). Patients with newly diagnosed epithelial OC will be enrolled in 4 different cohorts: A) Newly diagnosed high grade serous or endometroi…
Sponsor: Oncology Institute of Southern Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Simple blood test may open door to gene therapy for duchenne boys
Knowledge-focused OngoingThis is an observational screening study to evaluate the prevalence of anti-adeno-associated serotype 8 (AAV8) antibodies in participants with Duchenne muscular dystrophy (DMD).
Sponsor: REGENXBIO Inc. • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Night help for moms in recovery: can respite care improve sleep and Well-Being?
Symptom relief CompletedThis single arm pilot feasibility study will evaluate the implementation of overnight infant respite care and parenting skills to mothers with substance use disorders in the early postpartum period residing in residential substance use disorder treatment programs.
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Informed patients choose: surgery or not for torn ACL?
Knowledge-focused Stopped earlyThe purpose of the study is to evaluate the proportion of patients after rupture of the anterior cruciate ligament (ACL) of the knee, who will have functional or surgical management (PEC) in 1st intention, after having received appropriate information.
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Digital pill and app help At-Risk men stay on track with HIV prevention
Disease control CompletedThis is a single-arm, observational study of HIV-negative MSM with substance use disorder. Those who meet pre-screening criteria will attend a Screening Visit (Visit 1), where the informed consent process will be conducted and study eligibility will be confirmed. Eligible partici…
Phase 3 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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Sharper scans may make cancer radiation more precise
Knowledge-focused CompletedThis is a feasibility study investigating the image quality of a new, high-performance cone beam CT (CBCT) used for on-couch imaging during radiotherapy treatments.
Sponsor: Varian, a Siemens Healthineers Company • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Study questions when genetic counseling should happen: before or after testing?
Knowledge-focused CompletedAlthough pre-test genetic counseling is widely recommended and has come to dominate genetic counseling practice, tailored results-focused genetic counseling could both increase genetic counseling efficiency and improve genetic counseling outcomes for the growing number of patient…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Sep 10, 2026 01:00 UTC
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MS drug trial halted after failing to lower nerve damage
Disease control Stopped earlyThis was a Phase 2, randomized, double-blind, placebo-controlled 2 parallel-arm study to assess the effect on serum neurofilament light chain (sNfL), safety and tolerability of oral SAR443820 compared to placebo in male and female participants aged 18 to 60 years with relapsing-r…
Phase 2 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC