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116076 trials found · Page 5179 of 5804
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EEG timing could be key for ICU brain care
Knowledge-focused CompletedThe aim of this retrospective, observational, single-center study is to evaluate how electroencephalography (EEG) monitoring duration affects diagnosis and treatment in adult critical care patients.
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Jawbone graft showdown: which technique works best for dental implants?
Knowledge-focused CompletedHorizontal alveolar ridge deficiencies may prevent the placement of dental implants and often require bone augmentation procedures before implant treatment. Two techniques commonly used for horizontal ridge augmentation are the Split Box Technique and the Split Bone Block Techniq…
Sponsor: Marmara University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Can a simple dye test spot kidney trouble in the ICU?
Diagnosis CompletedThe objective of this study is to assess the feasibility of estimating the clearance of iohexol as an indirect measure of glomerular filtration rate in patients with unstable renal function in the intensive care unit through analysis of rich iohexol plasma kinetics.
Phase: PHASE3 • Sponsor: University Hospital, Tours • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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Trauma's hidden toll: stem cell failure may explain slow recovery in elderly
Knowledge-focused Recruiting nowTraumatic injury is a leading cause of morbidity and mortality in young adults, and remains a substantial economic and health care burden. Despite decades of promising preclinical and clinical investigations in trauma, investigators understanding of these entities is still incomp…
Phase: NA • Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can exercise fix tiny muscle blood vessels in COPD?
Knowledge-focused CompletedCOPD patients experiment a peripheral muscle dysfunction which impact their exercise tolerance and health-related quality of life. The capillary to fiber interface is reduced and impact the exercise capacity of the patients. While the muscle capillary creation in response to exer…
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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DNA registry aims to unlock secrets of testicular cancer
Knowledge-focused Recruiting nowThis study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also relatives and unrelated people without these tumors. This study will help us learn more about …
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Spinal lesions in early MS may signal future mobility trouble
Knowledge-focused CompletedThe purpose of this study is to evaluate the prognostic value of early focal lesions and early diffuse lesions on ambulatory disability progression within 5 years after clinical onset.
Phase: NA • Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists hunt for clues to predict when lung fluid dries up
Knowledge-focused ENROLLING_BY_INVITATIONSome patients that have a tunneled pleural catheter will not have the pleural fluid (water around the lung) return after some time (pleurodesis). The purpose of this study is to understand how the investigators can predict who will achieve pleurodesis and how this occurs by study…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Narcoleptic Kids' weight gain mystery: is metabolism to blame?
Knowledge-focused CompletedA significant weight gain and obesity are observed for most patients with narcolepsy, mainly at the beginning of the disease and narcolepsy in young children. There is no specific study on the population and the consequences of overweight in the lives of these long-term patients.…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Heart Infection's hidden brain damage tracked over time
Knowledge-focused CompletedPrimary objective: To describe the evolution of cerebral lesions in IE patients (number of patients with abnormal cerebral MRI in acute phase of IE and during follow-up).
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Can a simple numbing gel ease skin graft pain?
Symptom relief CompletedThe aim of the study is to Evaluate of the analgesic effect of ropivacaine in topical use at the thin skin graft donor site. For Patient needing a thin skin graft \< 320 cm2, randomization will be done in 2 groups, one receiving the standard treatment (20 mL of physiologic serum…
Phase: PHASE3 • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Scientists probe Inflammation's role in heart disease and diabetes
Knowledge-focused CompletedBackground: \- Cardiometabolic diseases are a combination of medical disorders that, when they occur together, increase the risk of heart disease and diabetes. Researchers want to learn if there is a relationship between these diseases and inflammation (redness, swelling, and pa…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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New drug combo tested for tough pancreatic cancer
Disease control CompletedThe study's overall objectives are to evaluate the safety of anakinra in combination with standard chemotherapy regimens in patients with pancreatic ductal adenocarinoma, as well as to collect preliminary immune modulation and clinical activity information, overall survival, and …
Phase: PHASE1 • Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Scientists hunt for genetic markers in ovarian, uterine, and cervical cancers
Knowledge-focused OngoingResearch of predictive clinical and biological factors in breast cancer : genomic, proteomic, mutation
Phase: NA • Sponsor: Institut Paoli-Calmettes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Can a smartphone app help PTSD smokers kick the habit for good?
Symptom relief CompletedThe primary goal of the study is to evaluate the use of a new smart phone application in preventing relapse to smoking among people with PTSD. The technology intervention will combine a mobile system to reward non-smoking, smoking cessation counseling, smoking cessation medicatio…
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Sperm vacuoles may reveal hidden DNA damage
Knowledge-focused CompletedIn men presenting sperm alterations, the selection of genetically undamaged spermatozoa need to be improved in order to increase the success of assisted reproduction treatments. The aim of this study is to determine whether the presence of sperm head vacuoles is associated with …
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New bandage aims to speed up healing of painful tailbone cysts
Symptom relief CompletedSinus pilonidal concern 26/100 000 young adults. It manifests after puberty, presenting as an acute abscess in approximately 50% of patients or as a discharging painful sinus. Patients may experience lengthy healing times resulting in considerable morbidity and disruption to a yo…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Scientists hunt for clues in breast cancer tissue to predict relapse
Knowledge-focused OngoingThis is an exploratory, translational, non-interventional and multi-centre biobank. The aim of the development of such a biobank is to identify potential biomarkers that are indicative of disease relapse.
Sponsor: Cancer Trials Ireland • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Can a stomach biopsy predict who will respond to gastric pacemakers?
Knowledge-focused Recruiting nowIn this research study, biopsy samples will be collected to provide more insight into the underlying cause of the motility disorders, help direct further investigation into the cause of the underlying condition, provide future prognosis and predict response to gastric electrical …
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Blood marker study aims to predict preterm birth risk
Knowledge-focused TerminatedAmong all patients hospitalized for Threatened Premature Delivery (TPD), the rate of premature birth (PB) before 37 weeks is about 42%, which reflects the inability to accurately identify patients at high risk of PB. Currently, no clinical or biological marker is recognized as th…
Phase: NA • Sponsor: Centre Hospitalier Departemental Vendee • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC