Could a common probiotic soothe IBS diarrhea?
NCT ID NCT07520422
First seen Apr 29, 2026 · Last updated Jun 20, 2026 · Updated 10 times
Summary
This completed trial tested whether a probiotic called Bacillus coagulans can help adults with mild to moderate IBS-D (diarrhea-predominant irritable bowel syndrome). Fifty participants took either the probiotic or a placebo capsule twice daily for 8 weeks. Researchers tracked changes in abdominal pain, stool consistency, and overall symptom severity using standard scales.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Medstar Speciality Hospital
Bangalore, Karnataka, 560092, India
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bacillus coagulans probiotic
What this could lead to
If it works, this could point toward a natural supplement to ease IBS-D symptoms like belly pain and diarrhea.
What could go wrong
This is a small, early-stage trial with only 50 people, so results may not apply to everyone. Probiotics can sometimes cause mild bloating or gas.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.