Could a Mucus-Busting supplement boost an IBS drug?

NCT ID NCT06727422

First seen Nov 11, 2025 · Last updated May 09, 2026 · Updated 27 times

Summary

This study tests whether adding a dietary supplement called NAC to the standard IBS-D drug rifaximin can better relieve symptoms like abdominal pain and diarrhea. About 225 adults with diarrhea-predominant IBS will receive either the combination or a placebo. The goal is to see if NAC helps break down mucus in the gut, allowing rifaximin to work more effectively.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.