POTS puzzle: scientists probe why carbs trigger dizziness

NCT ID NCT05375968

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why eating carbohydrates makes symptoms worse for people with Postural Tachycardia Syndrome (POTS), a condition that causes dizziness and rapid heartbeat upon standing. Researchers will measure blood flow changes in the abdomen after a sugary drink in 50 participants (25 with POTS, 25 healthy). They will also test whether blocking a gut hormone called GIP can reduce these symptoms. The goal is to understand the mechanism, not to test a new treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

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