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127005 trials found · Page 5167 of 6351
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Smart stethoscope listens for dialysis danger signs
Diagnosis CompletedThe prevalence rate of hemodialysis in Taiwan is the highest in the world, and the number of new cases of hemodialysis and the death rate are gradually increasing every year. Long-term hemodialysis patients must receive dialysis through the arteriovenous fistula. If the arteriove…
Sponsor: National Taiwan University Hospital • Aim: Diagnosis
Last updated Aug 06, 2026 00:00 UTC
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Could vitamin d boost fertility? new study investigates
Knowledge-focused CompletedBackground: About 1.5 million U.S. women of reproductive age are estimated to be infertile. Many more have difficulty getting pregnant. Menstrual cycles are an indicator of a woman's general health. Menstrual cycle changes may predict difficulties in getting pregnant. Researcher…
Phase 2 • Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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New study tracks why some kids with cerebral palsy suffer pain for months after surgery
Knowledge-focused Recruiting nowThe study purpose is to document the typical trajectory of perioperative pain experience in Cerebral Palsy (CP) and to identify important predictive factors for the development of chronic postsurgical pain. The main aims of the investigators are to: 1. Quantify the trajectory of…
Sponsor: Chantel Burkitt • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:54 UTC
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New baby formula aims to cut down Spit-Up
Symptom relief Recruiting nowThe aim of the study is to assess the effectiveness of this new formula on regurgitations and secondarily its effect on digestive tolerance through a randomized, controlled, double-blind trial against a comparator.
Sponsor: United Pharmaceuticals • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Peer power: can friends help close the colon cancer screening gap?
Knowledge-focused OngoingThe Black community has higher rates of colorectal cancer and lower rates of colorectal cancer screenings than whites. Getting screened through FIT testing may help catch colorectal cancer earlier, when it is easier to treat. MSK has created a program to help people who have been…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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HIV pill safety check: lower dose tested in Long-Term study
Disease control OngoingThe purpose of this study is to evaluate the safety and tolerability of DOR/ISL in adult participants with HIV-1 who had been previously treated with DOR/ISL in earlier clinical studies. There are no formal hypotheses to be tested in this study.
Phase 3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Can a smart bassinet help premature babies sleep better?
Symptom relief CompletedThe goal of this clinical trial is to compare sleeping in a SNOO Smart Sleeper bassinet (SNOO) with sleeping in traditional bassinet conditions in premature infants. The main questions it aims to answer are: 1. Do preterm infants who sleep in the SNOO have more quiet sleep? 2. D…
Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 26, 2026 17:09 UTC
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New vaginal device shows promise for yeast infections in small trial
Disease control CompletedThis is a multi-centre, multi-national study to evaluate the clinical performance and safety of treatment with Gedea Pessary in adult women with confirmed vulvovaginal candidiasis (VVC). The study population will consist of post-menarchal, pre-menopausal females, 18 years or old…
Sponsor: Gedea Biotech AB • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New video tool helps native hawaiian elders share end-of-life wishes
Knowledge-focused OngoingCommunication surrounding serious illness decision making is formalized in Advance Care Planning (ACP), a process involving verbal or written information designed to inform patients of possible medical options including palliative and hospice care services. Numerous studies have …
Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Gene therapy for knee pain: does it last?
Disease control OngoingThis is an observational study of the long term safety and efficacy of ICM-203.
Sponsor: ICM Co. Ltd. • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Simple shoe wedge may fix stiff knees after replacement
Symptom relief CompletedTotal knee arthroplasty (TKA) remains the only treatment for end-stage knee osteoarthritis, whereby the diseased ends of the bones comprising the knee joint are removed and replaced with prosthetic joint components. Approximately 500,000 of these procedures are performed annually…
Early phase 1 • Sponsor: University of North Carolina, Charlotte • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Bacterial wall chemical injected into tumors shows promise in early safety trial
Disease control CompletedThe purpose of this research study is to determine whether a sterile bacteria wall chemical, called lipopolysaccharide (LPS), can be injected safely into abdominal tumors during routine laparoscopic surgery performed as a preliminary procedure in patients who will subsequently un…
Phase 1 • Sponsor: Patrick Wagner, MD, FACS • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Vaccinated still got COVID: new study counts breakthrough cases
Knowledge-focused CompletedA novel coronavirus, SARS-CoV-2 (formerly known as the 2019 novel coronavirus \[2019-nCoV\]) was identified as the agent that caused an outbreak of pneumonia (termed COVID-19) in Wuhan, China in December 2019. The virus quickly spread to other countries and on March 11, 2020, the…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Soothing sounds after surgery: music may ease C-Section recovery
Symptom relief CompletedThis study aims to evaluate the effect of music played for women who undergo cesarean delivery on their early-stage pain, comfort, and mother-infant bonding levels. The study was conducted with 62 women who had cesarean deliveries and were hospitalized in the Obstetrics Unit of B…
Sponsor: Balikesir University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Heart patients learn to bounce back: new stress program shows promise
Symptom relief CompletedThe purpose of this study is to evaluate the feasibility and preliminary efficacy of the Promoting Resilience in Stress Management (PRISM) intervention in patients with adult congenital heart disease.
Sponsor: University of Washington • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New cancer drug combo tested in early human trial
Disease control CompletedThe goal of this clinical trial is to learn about IOS-1002 in patients with solid tumors. The main questions it aims to answer are: * To determine the safety and tolerability of various doses of IOS-1002 administered alone and/or in combination with KEYTRUDA® (pembrolizumab) in…
Phase 1 • Sponsor: ImmunOs Therapeutics AG • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Why do some Low-Risk leukemia patients relapse? scientists look to bone marrow cells for answers
Knowledge-focused CompletedAcute Myeloid Leukemia (AML) arises from the somatic acquisition of genetic alterations in hematopoietic progenitor or stem cells. One of the main hallmarks of AML is heterogeneity in terms of morphology, immunophenotype, cytogenetics, and molecular abnormalities, this heterogen…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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ICU stay throws body clocks out of sync, new study reveals
Knowledge-focused OngoingAbrupt changes to one's lifestyle disrupt biorhythms. Acute effects are well known from jet lag where transmeridian travel leads to insomnia, fatigue, irritability, gastrointestinal symptoms and other complaints. Several studies in the hospital environment reported dampened and m…
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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New wearable device aims to tackle MS bladder issues from home
Symptom relief OngoingThe goal is to investigate the feasibility and effects of adding "wearables for the bladder" devices to conventional pelvic floor physical therapy (PFPT) to bladder function, in people with multiple sclerosis (MS).
Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jul 10, 2026 00:00 UTC
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Refugee health check: rapid HIV and STI testing in ukraine war evacuees
Knowledge-focused CompletedBefore project launch, key materials were prepared, including informed consents, posters, informational leaflets, patient cards, social media posts, standard operating procedures, patient management plans and patient registries. Necessary medical supplies (rapid tests for HIV, sy…
Sponsor: Comenius University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC