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116076 trials found · Page 5148 of 5804
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Massive newborn seizure study launches in china
Knowledge-focused Recruiting nowA Multicentre, observational and cohort study to get the incidence of new-onset or newly-diagnosed seizure in neonatal population. EEG will used to record the change of brain electric activity and diagnose. Other data also will be collected since first seizure until confirmed dia…
Sponsor: Children's Hospital of Fudan University • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:11 UTC
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Could an antioxidant help gaucher disease? new study investigates
Knowledge-focused CompletedThe purpose of this study is to measure levels of blood and brain chemicals related to oxidative stress and inflammation in healthy volunteers and individuals with Type 1 Gaucher disease (GD1) to see if these levels are altered by GD1.
Phase: PHASE2 • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New shaver device may speed up uterine polyp surgery
Symptom relief CompletedIntrauterine pathologies are currently treated by hysteroscopic resection. In this surgical procedure, the intrauterine pathology is resected by a transcervical approach in several fragments using a mono or bipolar cove after distension of the uterine cavity and by endoscopic con…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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New stent could ease bladder troubles for spinal cord patients
Disease control CompletedDetrusor striated sphincter dyssynergia (DSSD) is defined as the persistence or increasing of the striated sphincter activity during voiding and characterizes the spinal cord injuries located under the protuberance. The standard treatment for DSSD is medical, either pharmacologic…
Phase: PHASE1, PHASE2 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 26, 2026 16:53 UTC
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New Muscle-Measuring device could help track facial paralysis recovery
Knowledge-focused CompletedThe objective of the research is to determine whether the MyotonPRO has a valid and reliable application in facial, head and neck surgery. In addition, the study aims to compare this new technology with current electromyography.
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Trimmed wire may lower lung collapse risk in nodule removal
Knowledge-focused CompletedThe goal of this observational study is to learn about the pneumothorax risk associated with the Pleural-Depth-Trimmed Hookwire (PDTH) technique in patients undergoing Preoperative CT-Guided Lung Nodule Localization (POCTGL). The main question it aims to answer is: Does the speci…
Sponsor: Chung Shan Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Xenon MRI aims to spot 'Good' fat in obesity fight
Knowledge-focused TerminatedThe primary goal of this study is to evaluate the feasibility of detecting Brown Adipose Tissue (BAT) in healthy subjects by using hyperpolarized xenon gas MRI. In this pilot study, MRI of BAT of healthy adult volunteers will be performed at 3 Tesla to assess image quality using…
Phase: PHASE1 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Hearing aid or surgery? small study pits both against otosclerosis
Disease control CompletedThis is a French pilot study in the Toulouse University Hospital that will include a minimum of 30 patients with proven unilateral or asymmetric otosclerosis. Each one will receive a hearing aid for a minimum of 2 months and then undergo otosclerosis surgery.
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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New knee implant tested for Long-Term success
Disease control OngoingLEGION™ Primary Total Knee System is CE-marked and marketed in all study regions. This study serves as post-market surveillance for LEGION™ Primary Total Knee System with the VERILAST™ bearing surface (OXINIUM™ femoral component with highly cross-linked polyethylene tibial insert…
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Before or after? study tests best time for insulin in type 1 diabetes
Disease control CompletedThe current study focuses on terms of use of Insulin Aspart, fast analogue of human insulin and commonly used in the treatment of type 1 diabetes, where it obtained the marketing authorization for this indication. In the patient who have an insulin pump, insulin Aspart is given d…
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Rural program aims to boost osteoporosis drug adherence
Disease control Recruiting nowAims: (1) to Establish the FLS services at the National Taiwan University Hospital Jinshan Branch. (2) To establish a anti-osteoporosis medication management service at Jinshan Branch. Method: From Aug., 2015, a fracture liaison services (FLSs) following the 13 'Capture the Frac…
Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Magnetic neck brace could replace CPAP for sleep apnea
Disease control Recruiting nowThe purpose of this study is to determine the safety and feasibility of the Magnap magnetic device in the treatment of obstructive sleep apnea (OSA).
Phase: NA • Sponsor: Michael Harrison • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New bladder pain cocktail tested – but study halted early
Symptom relief TerminatedThe purpose of this study is to determine if the combination product (URG101) is safe and effective versus its individual components (Heparin Sodium and Lidocaine Hydrochloride) for the treatment of Interstitial Cystitis/Bladder Pain Syndrome. The study is randomized and double-b…
Phase: PHASE2 • Sponsor: Urigen • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Full or empty bladder? study tests best way to protect organs during cervical cancer radiation
Knowledge-focused CompletedThe purpose of this study is to compare, for each patient, dosimetry of organs at risk (bladder, rectum, sigmoid, small bowel) in two bladder distension procedures (emptied by a urinary catheter or filled with 120cc) during PDR 3D image-guided brachytherapy of cervical cancer.
Phase: NA • Sponsor: Institut de Cancérologie de Lorraine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Ultrasound vs. MRI: which is better for catching liver cancer early?
Knowledge-focused CompletedThe investigators will investigate the usefulness of biannual ultrasonography versus annual non-contrast magnetic resonance imaging for surveillance of hepatocellular carcinoma in single arm patients.
Sponsor: JOON-IL CHOI • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New registry aims to unlock head and neck cancer secrets in asian patients
Knowledge-focused CompletedHead and neck cancers account for the sixth leading cause of cancers worldwide. The annual incidence of Head and neck cancers is more than 650,000 the patients each year. Head and neck cancers are associated with smoking, alcohol consumption, human papilloma virus (type 16 and 18…
Sponsor: Samsung Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Oxygen chamber treatment for diabetic kidneys falls short
Disease control TerminatedDiabetes kidney disease is a leading cause for end stage renal disease in the western world. To date no treatment that can reverse renal damage exists. Chronic hypoxia is one of the major key insults affecting the diabetic kidney, and many of the new treatments under study focus…
Phase: NA • Sponsor: Assaf-Harofeh Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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MS drug LEMTRADA under pregnancy microscope: what are the risks?
Knowledge-focused CompletedPrimary Objective: The primary goal of this registry is to assess the risk of spontaneous abortion in prospective enrolled women exposed to LEMTRADA for multiple sclerosis. Secondary Objective: The secondary goals of this registry is to assess maternal, fetal and infant outcom…
Sponsor: Genzyme, a Sanofi Company • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Vaginal cesarean risks under the microscope: new data collection completed
Knowledge-focused CompletedThis database has for objective to include the medical data of patients which underwent a vaginal Cesarean Section in our establishment. This collection will allow to determine the risk factors of the maternal morbi-mortality and to estimate the long-term results
Sponsor: Hôpital NOVO • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Scientists probe Gut's role in obesity: new study reveals how foregut may misfire
Knowledge-focused CompletedThe overall hypothesis of this proposal is that nutrient sensing in the foregut regulates metabolic hormone secretion and nutrient metabolism via enteric neural signals, and these mechanisms might be defective in obesity.
Phase: PHASE1 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC