Scientists squeeze and release heart failure patients to uncover exercise secrets
NCT ID NCT05764564
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how applying positive or negative pressure around the body affects exercise in people with heart failure with preserved ejection fraction. 27 participants, including healthy volunteers and heart failure patients, were tested non-invasively and some invasively. The goal was to measure changes in cardiac output, heart rate, and other factors during exercise.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors understand how body pressure changes affect exercise capacity in heart failure patients, potentially guiding future treatments.
What could go wrong
This is a small, early-phase study (27 participants) focused on understanding mechanisms, not testing a treatment. Results may not apply to all heart failure patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duke University Medical Center
Durham, North Carolina, 27710, United States