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127005 trials found · Page 5004 of 6351
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Calligraphy class lifts spirits: study tests art as depression remedy for seniors
Symptom relief CompletedThis study examines the effectiveness of an innovative cultural arts program in reducing depressive symptoms and age-related self-stigma among older Chinese as compared to service as usual through a randomized waitlist controlled trial.
Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated Jun 26, 2026 16:38 UTC
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Phone therapy shows promise for psoriasis patients battling depression
Symptom relief CompletedA single arm, pilot study in which all eligible participants will be enrolled in an 8-week coach-guided smartphone delivered CBT program. The full duration of the program, with follow-up interview, will be 9 weeks.
Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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ER timing could be key to saving heart attack victims
Knowledge-focused Recruiting nowThis study examines the impact of emergency department (ED) management on short-term outcomes of nontraumatic adult out-of-hospital cardiac arrest (OHCA) patients. Conducted by a research team at National Taiwan University Hospital and its affiliated hospitals, including branches…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Doctors get report cards on antibiotic use in urgent care
Knowledge-focused OngoingMany clinicians prescribe antibiotics for patients with acute respiratory infections even when antibiotics will not benefit the patient because the infection is due to a virus. To discourage this type of unnecessary antibiotic use, the investigators will assess whether it is help…
Sponsor: Daniel Livorsi • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New dental implant technique shows promise for bone loss patients
Disease control Recruiting nowThis retrospective study will evaluate the clinical performance of maxillary All-on-X(full-arch implant-supported rehabilitation) implant rehabilitation using stackable guided surgery and immediate loading. Implant survival and peri-implant outcomes will be assessed over a 2-year…
Sponsor: Menoufia University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New study aims to define safety of common bowel cancer surgery
Knowledge-focused CompletedThis SafeHeal study is designed to assess the overall safety of the low anterior resection (LAR) standard of care cancer treatment by establishing a definition of major complications. The current literature on standard of care reports adverse events/complications but does not pro…
Sponsor: SafeHeal Inc • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Blood in urine study aims to improve emergency care
Knowledge-focused Recruiting nowThis multicenter, prospective observational study will evaluate national and international practice variations (if present) in the emergency management of patients admitted to hospital with haematuria, inform a consensus guideline for best practice and provide evidence to design …
Sponsor: British Urology Researchers in Surgical Training • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Can a Self-Guided online course help parents and kids manage emotions?
Symptom relief CompletedThis study aims to evaluate the feasibility and acceptability of the eParenting CARE Program, an asynchronous, self-guided emotion-focused parenting intervention for parents of school-aged children (8-13 years). The eParenting CARE Program focuses on strengthening parent emotion …
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Laser showdown: which beam best battles gum disease?
Disease control CompletedAim of the study was to assess and compare the clinical and microbiological changes following Laser assisted new attachment procedure (LANAP®) using diode 940 nm versus ND:YAG 1064 nm, and to compare the outcome to conventional periodontal therapy
Sponsor: Nada Shaban • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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When is the best time for a pain block during spine surgery?
Symptom relief CompletedSpinal surgery patients generally have chronic pain in the preoperative period and are exposed to widespread and severe acute pain postoperatively. In spinal surgery patients, providing postoperative analgesia is important not only for the patient's comfort but also for preventin…
Sponsor: Aydin Adnan Menderes University • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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European launch of major AL amyloidosis registry aims to unlock disease mysteries
Knowledge-focused Recruiting nowA prospective patients' registry collecting all new cases of AL amyloidosis evaluated at referral Centers from across Europe and a sample sharing network will be created to study mechanisms of the disease through the use of advanced molecular technologies and big data analysis to…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Magnetic pulses may ease Post-Polio symptoms
Symptom relief CompletedThe study is planned to include a minimum of 26 patients with paralytic poliomyelitis who meet the PPS diagnostic criteria (1). Patients will be randomized into two groups, and one group will receive only the exercise therapy used in standard treatment, while the other group will…
Sponsor: Ege University • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Blood cell count may reveal who faces worst outcomes in rare autoimmune disease
Diagnosis CompletedAntisynthetase syndrome (ASyS) is a rare and heteregeneous overlapping connective tissue disease, characterized by myositis, interstitial lung disease (ILD), joint involvement, Raynaud's phenomenon and cutaneous manifestations ("mechanic's hands"). Over 50% of patients develop IL…
Sponsor: Central Hospital, Nancy, France • Aim: Diagnosis
Last updated Jun 27, 2026 12:10 UTC
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Braces aftermath: new study reveals best ways to save your enamel
Knowledge-focused Recruiting nowThis study investigates clinical approaches to orthodontic debonding and post-debonding finishing, focusing on enamel preservation. An observational epidemiological survey was conducted among dental professionals to assess commonly used techniques, instruments, and complications.…
Sponsor: University of Roma La Sapienza • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Sugar before surgery? new trial tests carb drink to protect kids from insulin spike
Disease control By invitation onlyIt is a double blinded randomized controlled trial interventional study, examining the effect of carb loading given prior to surgery on preventing post operative insulin resistance in pediatric patients undergoing elective surgery
Sponsor: Gadjah Mada University • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Statin shows promise for COPD inflammation in small trial
Disease control CompletedThis study aimed to evaluate the impact of statin therapy on the clinical consequences, as well as airway inflammation and radiological features, in severe chronic obstructive pulmonary cases.
Sponsor: Mohamed Salah El-Sayed • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New gaming gadget could level the playing field for kids with one hand
Symptom relief Recruiting nowThe goal of this clinical trial is to test a new one-handed video game controller adapter to determine if it helps improve how video games are played and enjoyed in children with an upper limb difference on one side. The main questions it aims to answer are: * Is performance imp…
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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AI takes on dentistry: can computers place implants better?
Disease control CompletedThis study at Future University in Egypt aims to compare two modern methods of placing dental implants: one using artificial intelligence (AI)-assisted computer planning and the other using conventional computer-guided planning. Participants who have missing teeth will receive de…
Sponsor: Future University in Egypt • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Simple memory test could spot dementia in Low-Education groups
Diagnosis CompletedThis study aimed to evaluate the validity, reliability, and diagnostic accuracy of the Turkish version of MoCA-B in distinguishing healthy controls, mild cognitive impairment (MCI), and dementia patients within a low-education population.
Sponsor: Antalya Training and Research Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 13:03 UTC
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Blood test clues could make antifungal dosing safer for transplant patients
Knowledge-focused CompletedIsavuconazole is an antifungal medicine used to prevent or treat serious fungal infections in people who have received a solid organ transplant (mainly lung, and also kidney or liver) or a hematopoietic stem cell (bone marrow) transplant. Because these patients take medicines tha…
Sponsor: Zhibin Xu • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC