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116076 trials found · Page 4938 of 5804
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Nerve block may help seniors recover faster after hip surgery
Knowledge-focused CompletedEarly postoperative rehabilitation is an important issue for total hip arthroplasty, especially in older patients. This retrospective clinical trial is to assess the impact of peripheral nerve block anesthesia versus general anesthesia in older patients' early recovery outcomes a…
Sponsor: RenJi Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:45 UTC
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C-Section recovery revolution: exercise may beat bed rest
Symptom relief CompletedThe purpose of this study is to test whether or not activity restrictions after a cesarean section are warranted and if exercise can improve postpartum wellness. This research study is being done because there is no science-based evidence to support postpartum activity restrictio…
Phase: NA • Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Mayo clinic launches major brain disease tracking study
Knowledge-focused ENROLLING_BY_INVITATIONThe investigators aim to learn more about symptoms suggestive of a neurodegenerative process.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Hidden breathing blockage found in severe asthma patients
Knowledge-focused CompletedThe first part will be a comparative cross-sectional study to identify the frequency of ILO and other comorbidites among participants with asthma compared to a group of reference subjects without asthma, matched for age- and gender and race. The second part will be a longitudina…
Sponsor: Haukeland University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Splash your way to stronger knees: water rehab beats land training?
Symptom relief CompletedThe goal of this clinical trial is to compare the applicability and effectiveness of an aquatic rehabilitation training program with a conventional land-based rehabilitation program in terms of lower extremity biomechanics and knee function in Anterior Cruciate Ligament Reconstru…
Phase: NA • Sponsor: Beijing Sport University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Could a common painkiller replace a stronger one for uterine procedures?
Symptom relief CompletedHysteroscopy is a procedure used to evaluate abnormalities within the uterus (intrauterine. Currently, hysteroscopy can be performed in an outpatient clinic setting according to established standards, known as office hysteroscopy. Although office hysteroscopy offers greater comfo…
Phase: PHASE4 • Sponsor: Indonesia University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Brain wave stimulation shows promise for memory boost
Knowledge-focused CompletedThis project will assess the feasibility of traveling wave transcranial alternating current stimulation (tACS) to modify working memory performance and large-scale brain connectivity in surgical epilepsy patients.
Phase: NA • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New study looks inside tumors during radiation therapy
Knowledge-focused Recruiting nowObservational, feasibility study investigating biological aspects in patients with liver metastasis from colorectal cancer undergoing treatment with SIRT, by translational analysis of biological samples.
Sponsor: Aarhus University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Hernia surgery drug trial halted early – what it means for patients
Prevention TerminatedPost-operative urinary retention (POUR) is a common complication after inguinal hernia repair with a reported incidence up 34%. It can be described as the inability to initiate urination or properly empty one's bladder following surgery. It is usually self-limited, but it require…
Phase: PHASE4 • Sponsor: Antonio Nocito, MD • Aim: Prevention
Last updated Jun 27, 2026 09:06 UTC
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Blood clot bandages may speed gum surgery recovery
Symptom relief CompletedThe objective of this study was to compare and evaluate the effects of concentrated growth factor (CGF) and advanced platelet-rich fibrin (A-PRF) clot membranes on palatal epithelial wound healing and postoperative discomfort following free gingival graft (FGG) harvesting.
Phase: PHASE2 • Sponsor: Ordu University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Women veterans: does stress fuel drinking? study investigates
Knowledge-focused CompletedThe purpose of the study "Stress, Emotion Regulation, and Alcohol in Women Veterans" is to learn about the effects of negative emotion and stress on behavior (including alcohol use) among women Veterans, including women with and without posttraumatic stress disorder. Additionally…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Back surgery tweak may keep new disc stable longer
Disease control Recruiting nowTo implant a complete lumbar disc prosthesis removal of the anterior portion of the annulus fibrosus is required. As the anterior portion of the annulus limits the movement in extension and axial rotation, we would like to know how much increase these two disc movements and also …
Phase: NA • Sponsor: University of Valencia • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Can a common drug reveal Parkinson's before symptoms start?
Knowledge-focused OngoingParkinson's disease (PD) is characterized by many non-motor symptoms that occur several years before the diagnosis, in particular idiopathic REM behavior disorder (iRBD), which is associated with autonomic impairment. The purpose of this study is to investigate the effect of trea…
Phase: PHASE2 • Sponsor: Cedars-Sinai Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Playtime prescription: new study tests if parent-led activity boosts health in kids with heart conditions
Knowledge-focused CompletedThis feasibility study will assess whether a 6-month, home-based, parent-led physical activity program, completed after surgical or catheterization treatment, enables young children with congenital heart defects (CHD) to achieve the recommended 180 minutes of daily physical activ…
Phase: NA • Sponsor: Children's Hospital of Eastern Ontario • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Scientists uncover how exercise leaves a lasting mark on muscle cells
Knowledge-focused OngoingThe goal of the study is to examine the ability of resistance or aerobic exercise training to "imprint" skeletal muscle cells in a manner which confers long-term changes in this tissue which in-turn contribute to improved metabolic health and functional capacity through epigeneti…
Phase: NA • Sponsor: AdventHealth Translational Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Sleep apnea may shield organs during aneurysm repair, study hints
Knowledge-focused Recruiting nowIschemia and reperfusion (I/R) injury during abdominal aortic aneurysm (AAA) repair is inevitable and may lead to postoperative multi-organ failure. Remote ischemic preconditioning (short periods of ischemia in anticipation of longer period of ischemia) may act protectively again…
Sponsor: St. Anne's University Hospital Brno, Czech Republic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Blood tests could make kidney cancer drugs safer and more effective
Knowledge-focused Recruiting nowThe purpose of this observational study is to assess the role of plasma concentration monitoring of treatment drugs for patients with metastatic renal cell carcinoma (mRCC) in terms of efficacy and side effects. It furthermore holds microbiome characterization of CPI-treated pati…
Sponsor: Niels Fristrup • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New registry tracks outcomes of keyhole heart valve procedure in 1,000 patients
Knowledge-focused Recruiting nowThis multinational, investigator-initiated registry aims to investigate clinical outcomes of patients undergoing transcatheter mitral valve replacement (TMVR). The registry primarily focuses on patients treated with TMVR in real-world clinical practice. Patients evaluated for TM…
Sponsor: Universitätsklinikum Hamburg-Eppendorf • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Could a tiny HPV shot still protect? small study tests lower dose
Knowledge-focused OngoingThis randomized phase IV trial compares fractional dose of bivalent HPV vaccine to fractional dose of nonavalent HPV vaccine among men and women aged 27-45 years in Seattle, Washington. Participants will have immune response assessed at baseline, 4 weeks, 6 months, 12 months, and…
Phase: PHASE4 • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Massive spanish study maps celiac disease trends across generations
Knowledge-focused CompletedPrevious studies have showed that Coeliac Disease (CD) prevalence is significantly higher in children compared with adults. The largest epidemiologic study carried out in Spain to date (n=4230) reported a higher CD prevalence in children (1:71) than in adults (1:357) during 2004-…
Sponsor: Hospital Mutua de Terrassa • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC