Kratom under the microscope: new study tracks immediate effects and withdrawal in regular users
NCT ID NCT06089980
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This observational study from Johns Hopkins University is watching 22 adults who regularly use kratom. On the first day, participants take their usual dose under supervision, then stop for about 2.5 days. Researchers measure physical and mental effects, including withdrawal symptoms, to better understand how commercial kratom products work and what happens when use stops.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21224, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
kratom
What this could lead to
If successful, this study could provide clearer data on kratom's acute effects and withdrawal symptoms, helping to inform future research on its safety and potential risks.
What could go wrong
This is a small, early observational study with only 22 regular users, so results may not apply to occasional users or the general public. It does not test any treatment or long-term outcomes.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.