Kratom under the microscope: new study tracks immediate effects and withdrawal in regular users
NCT ID NCT06089980
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This observational study from Johns Hopkins University is watching 22 adults who regularly use kratom. On the first day, participants take their usual dose under supervision, then stop for about 2.5 days. Researchers measure physical and mental effects, including withdrawal symptoms, to better understand how commercial kratom products work and what happens when use stops.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- kratom
- What this could lead to
- If successful, this study could provide clearer data on kratom's acute effects and withdrawal symptoms, helping to inform future research on its safety and potential risks.
- What could go wrong
- This is a small, early observational study with only 22 regular users, so results may not apply to occasional users or the general public. It does not test any treatment or long-term outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21224, United States
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