Scientists probe vagus nerve in real time to improve brain stimulation
NCT ID NCT06016686
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses a thin needle to record signals from the vagus nerve in awake adults with epilepsy who already have a vagal nerve stimulator implanted. Researchers aim to identify which nerve fibers are activated during stimulation and how different settings affect them. The goal is to better understand how VNS works and to guide future improvements. The study involves 60 participants and is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
vagal nerve stimulation (VNS) and microneurography recordings
What this could lead to
If successful, this could help design better vagal nerve stimulators for epilepsy and other conditions.
What could go wrong
This is a small, early-phase study focused on measuring nerve signals, not testing a treatment. It may not lead to any direct patient benefit.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••