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116076 trials found · Page 4812 of 5804
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Neck exercises may ease swallowing trouble
Symptom relief CompletedBackground: Cervicogenic dysphagia is a swallowing difficulty caused by cervical problems that negatively impact pulmonary health, and quality of life and may increase the risk of mortality. Study design: Randomized Controlled Study Purpose: The purpose was to explore the effect…
Phase: NA • Sponsor: Umm Al-Qura University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Veterans share war stories to build new therapy for moral wounds
Knowledge-focused OngoingDespite the VA's best efforts to treat the psychosocial impact of war, many combat Veterans report lingering difficulty reintegrating into meaningful post-deployment lives. War is among the most extreme forms of human experience but, for many, wartime trauma was treated using mod…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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New study aims to end guesswork in atrial fibrillation treatment
Knowledge-focused CompletedThis prospective observational study will include patients with atrial fibrillation that has indication for treatement with flecainide. Included patients are followed during a 12 month period. During the follow-up period they will have four clinical visits, during which clinical …
Sponsor: Lund University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:21 UTC
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Dental showdown: which crown technique saves Kids' teeth best?
Disease control CompletedThe purpose of this randomized clinical trial is to compare the clinical/radiographic success of Hall technique and modified Hall technique in the treatment of primary molars with deep dentine carious lesions in children (3-12-year-old). The secondary aim is to examine the effect…
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Shoulder implant under review: will it last 10 years?
Disease control TerminatedThis is a multicenter, retrospective and prospective, non-controlled post market surveillance study. The objectives of this study are to confirm safety, performance and clinical benefits of the T.E.S.S.® Version 3 Anatomic and Reverse Modular Total shoulder prosthesis and its ins…
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Good bacteria floss could fight gum disease
Disease control CompletedThis randomized, double-blind, crossover clinical trial evaluated the effect of a probiotic-containing nanofiber dental floss on subgingival red complex periopathogens and gingival health in periodontally healthy individuals. Thirty male participants underwent two 14-day flossing…
Phase: NA • Sponsor: St. Anne's University Hospital Brno, Czech Republic • Aim: Disease control
Last updated Jun 26, 2026 12:41 UTC
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Nerve block cuts opioid need after belly surgery
Symptom relief CompletedThis study evaluates whether adding an ultrasound-guided rectus sheath block (RSB) to general anesthesia can improve pain control after midline laparotomy. Adult patients undergoing midline incision laparotomy will be randomly assigned to receive either general anesthesia alone o…
Phase: NA • Sponsor: Udayana University • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Hormone clue to refeeding urine problem in anorexia teens
Knowledge-focused Recruiting nowPatients with restrictive-type anorexia nervosa who are admitted to the hospital for feeding often urinate excessive amounts. Others have changes in the way that they handle acid and base. These issues prolong hospitalizations. Current data suggest that one hormone--named secreti…
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Neck pain relief: stabilization exercises outperform traditional methods
Symptom relief CompletedThis randomized controlled trial investigated the effects of cervical stabilization exercises on head posture, pain, functional status, and voicing efficiency in patients with nonspecific chronic neck pain. Following a six-week exercise program, cervical stabilization exercises r…
Phase: NA • Sponsor: Suleyman Demirel University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Which autism drug causes less weight gain? small study aims to find out
Disease control CompletedThis study aims to compare two FDA approved medications (aripiprazole and risperidone) for the treatment of behavioral dysregulation in children with autism spectrum disorders. This trial, done in the context of routine clinical care, will seek to evaluate whether aripiprazole or…
Phase: PHASE4 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Brain injury study tracks tissue loss over three years
Knowledge-focused Recruiting nowThe goal of this observational study is to learn about changes in the brain of patients over the first 3 years following a traumatic brain injury (TBI). The main question it aims to answer are: \- How TBI effect the rate of brain tissue loss compare to healthy brain Participant…
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Can a doctor's referral to an exercise coach get people moving?
Knowledge-focused CompletedThe BewegtVersorgt project involved co-producing a physical activity referral scheme (PARS) for inactive persons with underlying non-communicable diseases. Various relevant actors of the German healthcare system (e.g., representatives of physicians, health insurance providers, sp…
Phase: NA • Sponsor: University of Erlangen-Nürnberg • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Could ambien help you heal faster after back surgery?
Symptom relief Recruiting nowThe purpose of this study is to evaluate if peri-operative zolpidem for posterior lumbar spinal fusion improves patient reported outcomes following surgery.
Phase: PHASE4 • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New device aims to ease painful birth scars without drugs
Symptom relief OngoingThe incidence of perineal scars after a pregnancy is high, either related to an episiotomy or to spontaneous perineal tears. These perineal scars can result in acute pain but also in chronic pain for some women. Medical treatment includes level 1 and 2 analgesics and, even for a …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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AI could sharpen IBD diagnosis by analyzing scans and videos
Knowledge-focused OngoingA retrospective and prospective, observational, non-interventional, cohort study to develop quantitative metrics from tools used as standard of care when diagnosing, assessing and monitoring patients with inflammatory bowel disease.
Sponsor: Perspectum • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New cholesterol drug inclisiran tested in everyday clinics
Knowledge-focused CompletedThis is a multicenter, non-randomized, non-interventional three-cohort study with prospective collection of primary data of treatment with newly initiated oral Lipid lowering treatment on top of a statin (Oral LLT cohort), newly initiated Inclisiran (Inclisiran cohort) and newly …
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Mud and movement: simple combo eases back pain in small study
Symptom relief CompletedThe aim of our study is to investigate the effect of peloidotherapy and exercise combination applied on patients with chronic low back pain on pain level, functionality and quality of life. Forty patients between the ages of 18-65 who were diagnosed with chronic low back pain wer…
Phase: NA • Sponsor: Istanbul Arel University • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Heart failure clues: study tracks 500 patients for 3 years
Knowledge-focused Recruiting nowPatients with HFpEF who have undergone meticulous clinical and instrumental evaluation (including diastolic exercise testing) between 2013 and 2020, will be followed up for at least 3 years.
Sponsor: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Could a UV laser smooth out this rare skin condition?
Symptom relief CompletedEfficacy of 308-nm excimer laser for primary localized cutaneous amyloidosis treatment in Asians, pilot study.
Phase: NA • Sponsor: Chulalongkorn University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New adjustable socket could help veterans walk more comfortably
Symptom relief Recruiting nowThe investigators do not yet know how a prosthetic socket with adjustable panels affects the performance of people with a lower limb amputation compared to a conventional prosthetic socket. The primary objective of this study is to compare an adjustable and conventional prostheti…
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC