New study tests smarter epidural dosing to ease labor pain

NCT ID NCT06494280

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial compares two ways of giving epidural pain relief during labor: giving a small dose every hour (bolus) versus a continuous drip. The goal is to see which method reduces sudden breakthrough pain in first-time mothers. About 240 women will take part, and their pain levels will be tracked throughout labor.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine and fentanyl (epidural)

What this could lead to

If the bolus method works better, it could mean fewer episodes of severe pain during labor for first-time mothers.

What could go wrong

This is a small, early-stage trial focused on a specific group (nulliparous women). Results may not apply to all labors, and the difference between methods might be small.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Breakthrough Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Holy Family Hospital

    RECRUITING

    Nazareth, Israel

    Contact

    Contact Email: •••••@•••••