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127005 trials found · Page 4742 of 6351
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Parent power: Family-Centered care may speed recovery for sick infants
Symptom relief CompletedThis research is an experimental study of randomized control with pre-test - post-test control group. The aim of this study is to determine the effect of family-centered care approach on physiological parameters and follow-up time in infants with respiratory failure diagnosed wi…
Sponsor: Ankara Etlik City Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 19:14 UTC
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RSV prevention drug shows promise in first year of use
Knowledge-focused CompletedThe goal of this observational study is to explore the impact of a new prevention medicine (nirsevimab) on the burden of Respiratory Syncytial Virus (RSV) disease in children under 2 years of age. The main question it aims to answer is: How has the incidence of RSV, and Emergenc…
Sponsor: Nicola Irwin • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:14 UTC
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Virtual reality exercise tested for MS patients
Knowledge-focused CompletedMultiple Sclerosis (MS) is the second most common neurological disorder in young adults after trauma. Treatments developed today can slow progression and reduce symptoms. Exercise therapy is a useful rehabilitation practice in MS to manage symptoms, restore function, optimize qua…
Sponsor: Acibadem University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:48 UTC
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Cheaper sinus lift for dental implants? gelatin sponge tested against bone graft
Disease control CompletedThe post-extraction pneumatization of the maxillary sinus often compromises the ability of the maxillary molar to the optimal recipient of dental implants as a consequence of the quantitative reduction of the vertical bone height and the reduced bone quality of the region posteri…
Sponsor: Beni-Suef University • Aim: Disease control
Last updated Jun 26, 2026 16:22 UTC
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Nurse-Led sedation for endoscopy proves safe in massive trial
Knowledge-focused CompletedThe purpose is to verify the effectiveness and safety of the painless digestive endoscopy mode led by anesthesia nurses under the guidance of anesthesiologists.
Sponsor: The Affiliated Hospital of Qingdao University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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No-Equipment floor exercises could ease COPD symptoms
Symptom relief OngoingChronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and functional disability, with pulmonary rehabilitation (PR) representing one of the most effective non-pharmacological interventions. However, access to conventional PR programs remains extremely limited…
Sponsor: Benazzouz Redouene Sid Ahmed • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Lung scanner may predict breathing tube removal success
Knowledge-focused CompletedAccurate prediction of readiness to liberate patients from mechanical ventilation remains challenging. Conventional indices such as the rapid shallow breathing index (RSBI) and maximal inspiratory pressure (MIP) often miss early signs of injurious breathing patterns or regional v…
Sponsor: Ruijin Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Ultrasound study aims to make spinal anesthesia safer for C-Sections
Knowledge-focused CompletedIntercristal line as palpation landmarks to identifying the vertebral level is frequently inaccurate.To find more safe and reliable body surface markers and convenient methods to be solved in clinical work.The investigators performed a two-stage study to evaluated the accuracy of…
Sponsor: The Third Affiliated Hospital of Guangzhou Medical University • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Can a tiny needle in the neck ease shoulder pain?
Symptom relief OngoingSegmental facilitation, originally proposed by Korr in the 1950s, suggests that certain spinal segments can become hyperexcitable, leading to chronic pain development. In a facilitated segment, neurons governing sensory, motor, and autonomic functions are in a state of heightened…
Sponsor: Texas Woman's University • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Gum disease treatment showdown: natural blood concentrate vs antibiotic microspheres
Disease control CompletedPeriodontitis is a chronic, biofilm-modulated inflammatory disease characterized by microbial dysbiosis and a dysregulated host immune response, eventually resulting in the gradual breakdown of the periodontal attachment apparatus. While non-surgical periodontal therapy (NSPT) re…
Phase 4 • Sponsor: Center for Advanced Rejuvenation and Esthetics • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Smart hydration during surgery may shield Seniors' brains
Knowledge-focused CompletedPostoperative cognitive decline remains a common and clinically significant complication among geriatric patients undergoing major abdominal cancer surgery. Age-related physiological vulnerability, impaired cerebral autoregulation, and perioperative hemodynamic instability contri…
Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Core training may speed groin recovery in young gymnasts
Symptom relief CompletedAdductor muscle strain is a common cause of groin pain in young athletes, particularly in gymnasts who frequently perform movements that require extreme hip flexibility and strength. Muscle imbalance around the hip joint and reduced core stability may increase the risk of adducto…
Sponsor: Aya Mohamed Elsheikh • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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New filling material takes on standard for Gum-Line cavities
Disease control CompletedThis study will be conducted to evaluate the clinical assessment of an alkasite based resin composite restorative material compared to resin modified glass ionomer based restorative material in class V cavities of anterior teeth over 12 months follow up using modified USPHS crite…
Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Global brain surgery matchmaker aims to help kids with rare movement disorders
Knowledge-focused By invitation onlyDBS Matchmaker (https://www.dbsmatchmaker.com) is a platform designed to connect clinicians worldwide who are treating rare movement disorders with deep brain stimulation (DBS). It facilitates global collaboration and knowledge sharing to enhance patient care by improving patient…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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New stomach bug treatment shows promise in 14-Day trial
Disease control Recruiting nowIn 2015, vonoprazan, a potassium-competitive blocker (P-CAB), was launched in Japan and used as an alternative for proton pump inhibitors (PPIs) for eradicating Helicobacter pylori. In recent studies, vonoprazan-based triple therapy significantly increased the eradication rate fr…
Sponsor: Soonchunhyang University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New algorithm could spot dangerous heart blockages without extra procedures
Knowledge-focused CompletedThis is a retrospective, single-center study to develop and validate an updated algorithm for computing fractional flow reserve from intravascular ultrasound images (IvusFFR v2.0). The study will use existing intravascular ultrasound (IVUS) images and corresponding invasive fract…
Sponsor: China National Center for Cardiovascular Diseases • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Laughter therapy shows promise for menopause brain fog
Symptom relief CompletedThe intervention will be conducted by Assist. Prof. Dr. Nurten ÖZÇALKAP. No invasive procedures will be performed; participants will engage in deep breathing, warm-up exercises, playful activities, and laughter exercises. The researcher holds an internationally certified training…
Sponsor: Agri Ibrahim Cecen University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Gene test aims to spot hidden infections after surgery
Diagnosis Stopped earlyChanges in host gene expression may provide additional information to diagnose postoperative infection and improve outcome after surgery. This study aims to validate the early diagnostic performance of specific gene signatures for differentiating infection from non-infected SIRS …
Sponsor: St. Antonius Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:24 UTC
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Simple discharge lesson boosts hysterectomy recovery, study finds
Symptom relief CompletedThis randomized controlled trial investigated the effect of discharge education based on Orem's Self-Care Theory on postoperative recovery quality and self-efficacy in women undergoing hysterectomy. The study used a pretest/posttest control-group design and included 64 randomly s…
Sponsor: Hitit University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New scan ladder technique tested for stronger dental implants
Disease control Completedthe study is concerned with assessing retrospectively the survival and complication rates of monolithic zirconia implant-supported fixed full arch dental restoration scanned using scan ladder scan body over a follow-up period of 1 year.
Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC