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127005 trials found · Page 4634 of 6351
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MRI tool may help surgeons avoid unnecessary ovary removal in girls
Knowledge-focused Recruiting nowWhen faced with an ovarian mass in a girl, conservative surgery (resection of the mass while preserving healthy ovarian tissue) via laparoscopy remains the most appropriate treatment option. However, this option is no longer indicated for malignant tumors, as this presents a risk…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Brain and body boost: Dual-Task training may ease Parkinson's symptoms
Symptom relief By invitation onlyThe aim of the study is to examine the effects of a structured, cognitive dimension-specific cognitive training combined with dual-task balance and gait training on balance, gait, and cognition in individuals with Parkinson's disease.
Sponsor: Gazi University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Can a smartphone app help kids with obesity stick to treatment?
Symptom relief CompletedThe goal of this feasibility study is to explore the needs of families with children with obesity and evaluate the impact of a combined intervention (children with obesity receiving pharmacological therapy in combination with the Adhera Caring Digital Program®) on treatment satis…
Sponsor: Adhera Health, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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New study aims to cut opioid use after back surgery with targeted nerve blocks
Symptom relief Recruiting nowLumbar microdiscectomy is a commonly used surgical procedure for treating herniated discs. Effective postoperative analgesia is crucial for early mobilization and functional recovery. Uncontrolled postoperative pain can delay recovery, increase the risk of opioid dependence, and …
Sponsor: Medipol University • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Could a simple enzyme supplement calm essential tremors?
Symptom relief By invitation onlyThis is a sponsor-initiated, single-arm, single-center clinical trial designed to evaluate the efficacy and safety of an ALDH-containing food supplement (PICOZYME ET) in patients with Essential Tremor (ET). Participants will consume the investigational product daily for three mon…
Sponsor: Pico Entech Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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New epidural method may improve labor pain control
Symptom relief CompletedChildbirth is an intense physical and psychological experience. Epidural analgesia (EP) remains the gold standard in labor pain management. However, continuous refinements are aimed at enhancing analgesic quality and mitigating adverse effects. In recent years, the dural puncture…
Sponsor: Medipol University • Aim: Symptom relief
Last updated Sep 03, 2026 00:00 UTC
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Can online coaching help parents tame toddler tantrums? small study says maybe.
Symptom relief CompletedThe goal of this feasibility study is to evaluate feasibility of Internet-delivered Parent-Child Interaction Therapy for parents of children 2-7 years with disruptive behaviors. The main questions it aims to answer are: 1. Could a brief online version of PCIT (iPCIT) be feasible…
Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Camera calibration study aims to sharpen prostate cancer imaging
Knowledge-focused CompletedThe main of this study is to demonstrate the feasibility of carrying out quantitative acquisitions regardless of the energy peak considered (113 keV (kiloelectronVolts) or 208 keV or a combination of the 2 energy peaks). A study on phantom will optimise the reconstruction paramet…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Brain monitor may help doctors Fine-Tune sedation during gut procedure
Knowledge-focused CompletedPatients undergoing ERCP have a wide range from patients with poor general condition and septicaemia findings to outpatients who come as day patients without any other additional disease. Rapid deterioration in vital signs may be encountered especially during sedation. In this pa…
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Can vibration straighten your neck? new study investigates
Symptom relief Recruiting nowThe primary goal of this clinical trial is to examine the effects of cervical vibrotactile stimulation intensity on abnormal head posture in people with cervical dystonia. The main question is: Does higher vibration intensity correct head posture to a greater extent than lower vi…
Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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Sleep pill may quiet Brain's cannabis cravings
Knowledge-focused CompletedThe goal of this study is to observe the impact of suvorexant, sold as BELSOMRA, on brain activity of people who frequently use cannabis. Suvorexant is an FDA-approved medication to treat insomnia. Researchers think that suvorexant may reduce activity in certain parts of the brai…
Phase 4 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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New supplement aims to speed up recovery for cyclists
Symptom relief Recruiting nowINTRODUCTION: Sports supplements and ergogenic aids are widely used for performance enhancement in recreational and professional sports. Athletes undergo intense training to improve their cardiorespiratory and muscular systems, aiming for positive adaptations. However, intensifi…
Sponsor: University of Westminster • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Can a short Self-Help course help stressed students get back on track?
Symptom relief Recruiting nowPrrospective, multi-center, randomized controlled trial of a brief, transdiagnostic, guided self-help intervention (Self-Help Plus) for university students who experience significant distress and are behind on their coursework. The intervention will be tested in terms of efficacy…
Sponsor: University of Padova • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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New study tests stronger membranes for better jawbone building
Disease control OngoingBone width is critical for successful implant placement, as thin bone increases the risk of bone loss. Various augmentation techniques-especially guided bone regeneration (GBR)-are effective in restoring bone volume using grafts and barrier membranes. Collagen membranes are commo…
Phase 4 • Sponsor: Saint-Joseph University • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Cool spray may ease sting of routine blood sugar tests
Symptom relief CompletedCapillary blood glucose measurement is a routine procedure in emergency departments, but it may cause pain and discomfort because it requires fingertip puncture. Vapocoolant spray is a rapid, noninvasive, and inexpensive method of topical analgesia that may reduce pain during min…
Sponsor: Abant Izzet Baysal University • Aim: Symptom relief
Last updated Jul 23, 2026 00:00 UTC
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Exercise app trial aims to unlock Chemo-Brain relief for cancer survivors
Knowledge-focused Recruiting nowThe growing U.S. cancer survivor population is projected to hit 26M by 2040. Chemotherapy represents an effective cancer treatment but can diminish cancer survivors' quality of life-particularly cognitive function-through select pathophysiological processes. Research on chemother…
Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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WhatsApp coaching boosts self-care for homebound elderly
Knowledge-focused Recruiting nowThe aim of the study is to evaluate the effectiveness and implementation of the mobile health (mHealth)-assisted, person-centred care (PCC) self-care support programme for homebound older adults. The researcher will compare PCC approach to a conventional care provider-led model. …
Sponsor: The Hong Kong Polytechnic University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:56 UTC
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Single dose of methadone may ease pain after brain surgery
Symptom relief Recruiting nowPostoperative pain is prevalent after intracranial surgery. Patients undergoing craniotomy are typically managed with short acting opioids to enable early and reliable post-operative neurological exam as well as avoid the risk of respiratory depression. However, a plethora of stu…
Early phase 1 • Sponsor: University of Virginia • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Needle-free vein pressure check for kids tested in new study
Knowledge-focused Recruiting nowCentral Venous Pressure (CVP) is a standard parameter for hemodynamic monitoring and is currently measured through the insertion of a catheter. The pediatric population is especially vulnerable to risks associated to this invasive procedure, including infection, thrombosis, and p…
Sponsor: Compremium AG • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:31 UTC
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Pre-Sleep protein may boost athletic recovery better than Post-Workout
Symptom relief CompletedThis randomized controlled trial aimed to investigate the effects of casein supplementation timing on post-exercise recovery and exercise performance in trained football players. Participants were allocated into three groups: pre-sleep casein ingestion, post-exercise casein inges…
Sponsor: Serdar Bayrakdaroğlu • Aim: Symptom relief
Last updated Jun 26, 2026 15:34 UTC