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116076 trials found · Page 4634 of 5804
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New gel may help men with ED after prostate surgery
Symptom relief CompletedThe investigators are doing this research to evaluate the efficacy and safety of topical MED3000 therapy in men with persistent erectile dysfunction 1.5 to 4 years following radical prostatectomy surgery.
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Weight-Loss drug trial for pancreatic cancer halted early
Symptom relief TerminatedMulticenter, double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of anamorelin HCl. Approximately 100 subjects with advanced PDAC and cachexia will be randomized 1:1 to anamorelin HCl 100 mg or placebo, taken orally once daily (QD) for a total o…
Phase: PHASE2 • Sponsor: Lahey Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Could reusing your own blood after bypass cut donor transfusions?
Disease control CompletedIn our study, the impact of administering autologous blood remaining in the cardiopulmonary bypass system during coronary artery bypass surgeries will be evaluated using the ROTEM device to assess its effect on coagulation parameters. Additionally, the influence of this autologou…
Phase: NA • Sponsor: Ataturk University • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Could eggshells fix Kids' cavities? new trial tests natural pulp treatment
Disease control Recruiting nowTo assess \& compare clinical \& radiographic effects of Eggshell Powder, Biodentine and MTA as pulpotomy agents in primary teeth.
Phase: NA • Sponsor: Tanta University • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Needle or no needle? study pits microneedling against facial exercises for wrinkle reduction
Symptom relief CompletedThis randomized controlled trial compared the effectiveness and safety of fractional microneedling radiofrequency (FMR) and facial muscle exercises (FME) for facial rejuvenation in females with mild to moderate facial aging. Forty participants aged 32-65 were randomized to either…
Phase: NA • Sponsor: Kasr El Aini Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Tape trick eases back pain and improves balance in stiff spine disease
Symptom relief CompletedThis study will investigate the effects of kinesio taping on pain, posture, balance, and respiration in ankylosing spondylitis, and compare its effects with routine home exercises given to this group.
Phase: NA • Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Fiber supplements may alter gut bacteria linked to colon cancer risk
Knowledge-focused Recruiting nowThis clinical trial tests whether daily fiber supplementation will change the mucosal microbiome of the colon. The microbiome are microorganisms that live in the human gut. They serve a vital role in maintaining health. Certain microbial strains are associated with the growth of …
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Video tool lets stroke patients skip clinic visits for movement checks
Knowledge-focused CompletedThe purpose of this study is to develop and validate a novel video-based postural evaluation tool designed to objectively measure the quality and dynamics of the Sit-to-Stand (STS) motion in stroke patients, specifically allowing physical therapists to monitor patient progress re…
Sponsor: Sahmyook University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can a walking program ease chronic pain? new study tests feasibility
Symptom relief CompletedThe investigators aim to conduct a randomized controlled trial to test the feasibility of a mind-body walking program compared to a health education program for individuals with chronic musculoskeletal pain. The investigators will assess the feasibility of recruitment procedures …
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Practice makes perfect: can simulated drills save newborns?
Knowledge-focused CompletedBackground: Effective teamwork and quality care are crucial for patient safety overall. Simulation-based team training offers a valuable approach to improving communication, coordination, and decision-making among healthcare professionals, leading to better outcomes and a safer …
Phase: NA • Sponsor: University of Aarhus • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Rolled gum flap could replace painful graft for dental implants
Disease control Recruiting nowThe aim of the study is to clinically and radiographically evaluate and compare two techniques to augment soft tissues: the conventional subepithelial connective tissue graft technique and a novel denuded interpositional pedicled rolled flap technique (DIPRF) These techniques wil…
Phase: NA • Sponsor: Misr International University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Phone therapy shows promise for cutting alcohol use in young adults
Symptom relief OngoingObjective: The proposed study aims to develop a protocol of telephone-based Acceptance and Commitment Therapy (ACT) for Alcohol Use Disorder (AUD) and examine the feasibility of implementing such intervention among the Hong Kong Chinese young adults with AUD. Study design: A ran…
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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AR goggles could save kids from medication errors in ambulances
Knowledge-focused OngoingThe primary objective of this research study is to use simulated pediatric emergencies to test the effectiveness of a drug dosing safety system for EMS providers by comparing usual care to use of an augmented reality device.
Phase: NA • Sponsor: Western Michigan University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Scientists examine immune clues in ovarian cancer
Knowledge-focused CompletedThe study seeks to evaluate the presence and correlation with clinical outcome of several components of adaptive immunity (TILs, TLS, plasma cells and PD-L1 expression) in tumor specimens of patients with EOC treated with carboplatin/paclitaxel chemotherapy.
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Robot rumble: which machine does lung surgery better and cheaper?
Knowledge-focused OngoingThe goal is to compare clinical outcomes, hospital costs, and cost-utility in patients undergoing anatomical lung resections with DaVinci Xi vs Versius platforms The main questions it aims to answer are: * Do patients that undergo an anatomical lung resection with DaVinci Xi ha…
Sponsor: Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Shivering showdown: which drug wins for surgery patients?
Symptom relief CompletedShivering is recognized as an undesirable effect of spinal anesthesia. Patients undergoing gynecological surgeries may experience increased physiological stress due to perioperative shivering. This condition can lead to serious complications such as increased oxygen consumption, …
Phase: NA • Sponsor: Sargodha Medical College • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Scientists hunt for hidden clues in mysterious bleeding disorders
Knowledge-focused Recruiting nowThe goal of this prospective cohort is to identified specific biological patterns in patients with a bleeding of unknown cause and to study the specific mechanisms of the bleeding disorder for each subset of patients.
Sponsor: University Hospital, Geneva • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Can a computer predict liver cancer before it strikes?
Knowledge-focused OngoingThe goal of this prospective observational cohort study is to validate previously developed Hepatocellular Carcinoma (HCC) risk prediction algorithms, the Liver Risk Computation (LIRIC) models, which are based on electronic health records. The main questions it aims to answer ar…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Brain insulin may hold key to schizophrenia's cognitive fog
Knowledge-focused Recruiting nowCognitive impairment (such as challenges in thinking and memory) is a core aspect of schizophrenia (SCZ), contributing to disability and poor functional outcomes. Additionally, almost half of the patients with SCZ are obese, the prevalence of type 2 diabetes is 3-6 times higher, …
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Can a Blood-Saving device cut transfusions in Kids' spine surgery?
Knowledge-focused Recruiting nowSpine surgery for scoliosis correction in pediatric patients is a major procedure associated with a high risk of perioperative blood loss. Homologous blood transfusion carries inherent risks, including immunological reactions, infections, and increased healthcare costs. Identifyi…
Sponsor: Mehdi Trifa • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC