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127005 trials found · Page 4630 of 6351
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New study aims to unlock the secrets of walking after amputation
Knowledge-focused Recruiting nowThe experience of amputation leads to a deterioration in quality of life, with undeniable somatic and functional repercussions. The result is a reduction in general mobility, increased metabolic energy requirements and a feeling of discomfort and pain. The rehabilitation objectiv…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Can a single workout or muscle zaps boost bone health in dentists?
Knowledge-focused CompletedDue to their high workload and unfavorable working position, young female dentists are particularly at risk of cardiometabolic diseases and an early reduction in bone mineral density (BMD). With focus on the latter issue, short bouts of resistance exercise with high strain magnit…
Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Music and breathing beat anxiety in nursing students
Symptom relief CompletedObjective: This study was conducted to evaluate the effectiveness of music therapy and 4-7-8 breathing exercises in managing anxiety among nursing students during IV drug administration education. Method: This study was conducted using a randomized controlled experimental resear…
Sponsor: Inonu University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Ultrasound study probes pelvic floor differences in nerve pain
Knowledge-focused CompletedThis study will compare superficial pelvic floor shear-wave elastography between healthy women and women with pudendal neuralgia.
Sponsor: Comenius University • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Dentists test three common irrigants to ease root canal pain
Symptom relief CompletedPain is the main reason patients visit a dentist for root canal treatment. Sometimes, patients experience pain between visits, which can make the treatment uncomfortable and stressful. This study aims to compare three commonly used root canal irrigants-sodium hypochlorite, hydrog…
Sponsor: CMH Multan Institute of Medical Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Which position is safer for breathing tube placement in neck mass patients?
Knowledge-focused CompletedThis study is aimed to compare different tools of endotracheal intubation in supine versus lateral position in patients with neck masses. Primary outcome: is time taken for intubation. Secondary outcomes: * The success rate of first intubation trial. * Hypoxia, Spo2 \< 90%. * …
Sponsor: Aswan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Sound waves for back pain? new device tested in small trial
Symptom relief Recruiting nowThis study will be a double-blinded, two-arm, prospective, randomized controlled pilot feasibility study in 40 evaluable subjects (20 in each arm) at one study site within the United States. Subjects in Arm 1 will receive unilateral Discogen treatment; subjects in Arm 2 will rece…
Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Hidden Gut-Brain issues common in kids with IBD, study finds
Knowledge-focused CompletedThe medical management of inflammatory bowel disease (IBD) has evolved over the years thanks to the newly available therapies and the biochemical and endoscopic monitoring of the disease. Several in-remission IBD patients still complain of gastrointestinal symptoms, suggesting a …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Ear needles may soothe dry eyes, small study suggests
Symptom relief CompletedDry eye symptoms can cause various discomforts in the eyes and/or visual disturbances. This condition not only limits daily personal activities and reduces quality of life and mental health but also has negative economic impacts on families and society. Currently, complementary a…
Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Ear needles for back pain? new study tests battlefield acupuncture
Symptom relief CompletedThe Global Burden of Disease's 2023 study shows that lower back pain affects over 619 million people worldwide, with projections reaching 843 million by 2050. It is a common symptom of lumbar spine degeneration, with 84.2% of patients experiencing it. To address this issue, Vietn…
Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Symptom relief
Last updated Jun 26, 2026 19:02 UTC
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Nattokinase: a natural sleep and heart booster?
Symptom relief Recruiting nowNattokinase has been confirmed by many experiments to have a thrombolytic effect, but there are currently very few studies on nattokinase's effect on gut microbiota, sleeping status, and age-related cognitive function. Therefore, this study intends to explore the effect of nattok…
Sponsor: Taipei Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Herbal tea showdown: can two plants tame metabolic syndrome?
Symptom relief CompletedThe study evaluates the effects of VitalPLANT and Helichrysum italicum on different components of the metabolic syndrome. The components of metabolic syndrome will be measured at baseline and one week after daily consumption of either VitalPLANT alone or either VitalPLANT+Helichr…
Sponsor: University of Primorska • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Simple nerve stretches may boost carpal tunnel relief
Symptom relief CompletedThis randomized, clinical, single-blinded, controlled study will initially planned to include 86 patients diagnosed with carpal tunnel syndrome who applied to Kütahya Health Sciences University, Evliya Çelebi Training and Research Hospital, Physical Medicine and Rehabilitation ou…
Sponsor: Kutahya Health Sciences University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Pilates eases 'Text Neck' in school kids, small study finds
Symptom relief CompletedText Neck' is a term used to describe a posture that is caused by leaning forward for long period of time such as reading or texting on smartphone. Neck pain, discomfort, reduced function and limited range of motion are the signs of text neck. Forward head posture is the most com…
Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Soft brain probe tested in humans for first time
Knowledge-focused CompletedThe goal of this interventional study is to find out the feasibility of whether the soft neural probe can be used in human brain tissue. The main questions it aims to answer are: * Are there any problems when inserting the soft neural probe into brain tissue? * Can the soft neur…
Sponsor: Axoft, Inc. • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:33 UTC
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Super whey protein could fight Age-Related muscle loss
Knowledge-focused Recruiting nowOccupying \~45-55% of body mass, skeletal muscle is the largest organ of the body and plays a pivotal role in locomotion, structural support and whole-body metabolic health. Additionally, skeletal muscle serves as the largest reservoir of amino acids (AA), which negatively adapts…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New pain pumps aim to ease recovery after knee replacement
Symptom relief By invitation onlyThis is a prospective, randomized clinical trial evaluating three groups. The groups are: Group 1 (Control): Subjects that receive only the existing standard-of-care multimodal pain management protocol and do not receive post-operative intra-articular catheter. Group 2 (Investi…
Phase 4 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Can a surgical flap prevent a common complication after throat cancer surgery?
Knowledge-focused OngoingSalvage total laryngectomy (TL) and total pharyngolaryngectomy (TPL) are the gold standard for most recurrent laryngeal and hypopharyngeal tumors as well as in patients with contraindication for chemoradiotherapy (CRT). Free or pedicled flaps are the two mandatory options for pha…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Which nose surgery works best? new study compares outcomes for 1,100 patients
Knowledge-focused CompletedThe purpose of this study is to assess and compare the clinical outcomes associated with common surgical interventions for the treatment of nasal airway obstruction (NAO).
Sponsor: Aerin Medical • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Tooth resin treatment soothes sensitive teeth in children
Symptom relief CompletedThis study evaluates the effect of resin infiltration on dental sensitivity, quality of life, and satisfaction in children aged 7-14 with enamel defects in their front teeth. Forty children received treatment, and outcomes were measured through sensitivity tests and questionnaire…
Sponsor: Gizem Tıraşçı • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC