Can a surgical flap prevent a common complication after throat cancer surgery?

NCT ID NCT07287865

Ongoing Knowledge-focused Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at 400 people who had surgery to remove throat cancer (laryngectomy or pharyngolaryngectomy). The goal is to find out which factors, like using a surgical flap or muscle loss (sarcopenia), increase the risk of a fistula—a leak that can cause infection. Researchers hope to better predict and prevent this complication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surgical flap (pedicled or free flap)
What this could lead to: If successful, this could help doctors identify which patients benefit most from flap surgery to prevent fistulas after laryngectomy.
What could go wrong: This is an observational study, not a treatment trial. It won't directly test a new therapy, and results may not change practice immediately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypopharyngeal carcinoma laryngeal disorder laryngeal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LARYNGEAL AND HYPOPHARYNGEAL TUMORS

Contacts and locations

Locations

SC Otorinolaringoiatria - Fondazione IRCCS Policlinico San Matteo, Pavia

Pavia, Pavia, 27100, Italy

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