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116076 trials found · Page 4586 of 5804
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Pole walking improves gait in children with brain injury
Symptom relief CompletedNordic walking is a physical activity consisting of walking with poles similar to ski poles. The poles are designed for the purpose of activating the upper body during walking. The poles are equipped with rubber or spike tips and the walking itself resembles.
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Blue light may boost brain stimulation for Tough-to-Treat epilepsy
Knowledge-focused Recruiting nowVagus nerve stimulation (VNS) is an adjunctive treatment for refractory epilepsy. Although widely used, there is still a substantial number of patients with insufficient response. Light, and particularly blue light, can stimulate alertness, attention and cognition through modulat…
Phase: NA • Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:38 UTC
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Whipple surgery aftermath: scientists track hidden changes in the remaining pancreas
Knowledge-focused CompletedPeriampullary malignant neoplasms are among the most lethal gastrointestinal tumors. They are usually diagnosed at advanced stages and require complex surgical treatment. Pancreaticoduodenectomy, the standard procedure for resectable cases, significantly impacts nutritional statu…
Sponsor: Marco Aurélio Ribeiro, PhD • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:26 UTC
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Which block beats breast surgery pain? ESP vs RIB showdown
Symptom relief CompletedIn this study, the investigators compared ultrasound-guided erector spinae plane (ESP) block and rhomboid intercostal block (RIB) on postoperative analgesic effect in unilateral breast surgery.
Phase: NA • Sponsor: Kocaeli University • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Could Mom's sitting and sleeping habits shape Baby's heart health?
Knowledge-focused Recruiting nowThere is growing evidence that maternal health and behaviors in pregnancy, such as pre-pregnancy obesity, excessive gestational weight gain, poor diet, smoking, and adverse pregnancy outcomes, are linked to fetal programming for obesity and cardiovascular disease (CVD) risk in th…
Sponsor: Kara Whitaker • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Can a smartphone app ease the burden on bone marrow transplant caregivers?
Symptom relief OngoingThe goal of this research study is to determine whether a self-administered, psychosocial mobile application (CARE app) is effective at improving the quality of life and experience of caregivers of patients receiving hematopoietic stem cell transplantation (HCT).
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Shockwaves could soothe stiff necks
Symptom relief CompletedPurpose: The study aimed to determine whether adding extracorporeal shockwave therapy (ESWT) to a standardized physiotherapy program provides additional benefits for patients with chronic mechanical neck pain. Specifically, it examined effects on pain intensity, pressure pain th…
Phase: NA • Sponsor: Benha University • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Video link cuts ER wait and violence in psychiatric emergencies?
Knowledge-focused OngoingThe goal of this observational study is to examine the effect of using a video link for evaluation of patients in the psychiatric emergency room. Under current Israeli law, the attending physician must come in to physically examine the patient before they can be admitted involunt…
Sponsor: Hebrew University of Jerusalem • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Diaphragm mystery: could your breathing muscle explain shortness of breath?
Knowledge-focused Recruiting nowDyspnea is among the most common symptoms in patients with respiratory diseases such as Asthma, chronic obstructive pulmonary disease (COPD), Fibrosis, and Pulmonary Hypertension. However, the pathophysiology and underlying mechanisms of dyspnea in patients with respiratory disea…
Sponsor: RWTH Aachen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Small study tests blood sugar targets to prevent lows during exercise in type 1 diabetes
Knowledge-focused TerminatedDespite major technological advances in type 1 diabetes (artificial pancreas), the management of hypoglycemia remains a major challenge, especially during and after physical activity. The primary outcome is to determine the temporary blood glucose (BG) target to be set 60 minutes…
Phase: NA • Sponsor: Institut de Recherches Cliniques de Montreal • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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New online therapy eases MS-Related anxiety and depression
Symptom relief CompletedMultiple Sclerosis (MS) is a chronic autoimmune disease that affects the brain and spinal cord, often leading to unpredictable symptoms and significant emotional distress. Many people with MS experience anxiety, depression, and difficulties in coping with the challenges of the di…
Phase: NA • Sponsor: American University of Beirut Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Stroke rehab measurement tool put to the test
Knowledge-focused CompletedThis prospective multicenter study evaluated the construct validity and responsiveness of the Fugl-Meyer Assessment (FMA) in individuals with subacute stroke undergoing inpatient rehabilitation. A total of over 100 participants were assessed at admission and discharge using FMA a…
Sponsor: Fondazione Don Carlo Gnocchi Onlus • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Quick ultrasound check could prevent deadly breathing tube mistakes
Diagnosis Recruiting nowThe clinical importance of airway management has gained prominence in the last decade in most scientific societies with the aim of improving the standard of care. The WHO has focused guidelines for "Safety in Surgery", which attempt to encompass all methods that predict and reco…
Sponsor: Clinica Universidad de Navarra, Universidad de Navarra • Aim: Diagnosis
Last updated Jun 27, 2026 12:07 UTC
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New program helps HIV+ asian american men manage health with family support
Knowledge-focused CompletedHIV infection rates are on a rapid rise within Asian Pacific Americans (APA) communities, with 80% of new infects being men. The purpose of this study is to adapt and evaluate the feasibility of a 4-session, 4-week family-informed self-management intervention protocol to promote …
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Breathing Helium-Oxygen may unlock exercise secrets for heart failure patients
Knowledge-focused Recruiting nowThe overall purpose of this study is to investigate whether pulmonary limitations that increase the oxygen (O2) cost of breathing impact dyspnea on exertion (DOE) and peak exercise capacity in patients with HFpEF and obesity. As per investigator's hypothesis, obesity is likely a …
Phase: NA • Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Hidden heart condition found in many with stiff heart failure
Knowledge-focused CompletedCardiac amyloidosis (CA) has recently been reported as a common cause of heart failure with preserved left ventricular ejection fraction (HFpEF), with a prevalence of 6% in elderly HFpEF patients. However, the diagnosis of CA is still challenging and requires multiple costly inve…
Sponsor: University Tunis El Manar • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Massive study to reveal hidden costs of Alzheimer's in china
Knowledge-focused Recruiting nowAlzheimer's disease (AD) presents a significant socio-economic challenge globally, with China experiencing a notable rise in its prevalence. This study addresses critical gaps in understanding AD's economic burden and quality of life (QoL) impacts on patients and caregivers in Ma…
Sponsor: Xuanwu Hospital, Beijing • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Magnetic pulses reveal how the brain rewires its visual centers
Knowledge-focused CompletedThe goals of this study are to 1) use EEG steady-state visual evoked potentials as a noninvasive measure of the neuroplasticity induced by repetitive transcranial magnetic stimulation (rTMS), 2) use visual contrast detection paradigms as a behavioral measure of rTMS effects, and …
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Lyme disease in pregnancy: new study tracks baby brain development
Knowledge-focused Recruiting nowThe purpose of this pilot study is to assess the feasibility of longitudinal neurodevelopmental evaluation of fetuses and infants exposed to Lyme disease in utero. Participants with Lyme disease or Post-Treatment Lyme Disease Syndrome (PTLDS) will be recruited during pregnancy. P…
Sponsor: Children's National Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Online happiness classes may ease cancer Survivors' worst fears
Symptom relief CompletedThe goal of this clinical trial is to learn whether a group positive psychology-based educational program can reduce fear of cancer recurrence in women with a history of breast cancer who have completed primary treatment (surgery, chemotherapy, and radiotherapy). The main questi…
Phase: NA • Sponsor: Golestan University of Medical sciences • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC