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New blood test may help doctors time immune boosts in ICU

NCT ID NCT06549374

Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study monitors immune function in 200 intensive care patients after severe trauma, high-risk surgery, or respiratory distress. Researchers use a simple, automated blood test to measure interferon-gamma levels, which indicate immune strength. The goal is to identify when patients are most vulnerable to infections, so future treatments can be given at the right time. No experimental treatment is provided in this study.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patient included will be adult patients admitted to intensive care after severe trauma, high-risk surgery, or presenting with acute respiratory distress

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 years or older * Patients admitted to intensive care after severe trauma, or presenting with acute respiratory distress, or undergoing cardiac, vascular, or digestive surgery with planned postoperative intensive care. Exclusion Criteria Exclusion Criteria: * Expressed opposition from the patient, a relative (if applicable), or their legal representative (guardian, curator) * Pregnant woman * Hemoglobin less than 7g/dl at inclusion

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Conditions

The condition(s) this trial relates to.

Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intensive care

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    7 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Reanimation department, Annecy Genevois hospital

    NOT_YET_RECRUITING

    Annecy, 74370, France

  • Reanimation department, Clermont-Ferrand Hospital

    NOT_YET_RECRUITING

    Clermont-Ferrand, 63000, France

  • Reanimation department, Lyon hospital

    NOT_YET_RECRUITING

    Lyon, 69003, France

  • Réanimation cardio-chirurgicale - Pitié-Salpêtrière hospital

    RECRUITING

    Paris, Île-de-France Region, 75013, France

  • Réanimation chirurgicale Gaston Cordier - Pitié-Salpêtrière hospital

    RECRUITING

    Paris, Île-de-France Region, 75013, France

  • Réanimation chirurgicale Husson Mourrier - Pitié-Salpêtrière hospital

    NOT_YET_RECRUITING

    Paris, Île-de-France Region, 75013, France

  • Réanimation neuro-chirurgicale - Pitié-Salpêtrière hospital

    NOT_YET_RECRUITING

    Paris, Île-de-France Region, 75013, France

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