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116076 trials found · Page 4560 of 5804
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Could changing your gut bacteria protect your memory?
Knowledge-focused CompletedThe GW SMHS supports research in complementary and integrative approaches to treatment of sickness and disease and for health promotion. Sometimes, research may involve asking questions of patients, students, and health providers. In this study, individuals are being asked to par…
Sponsor: George Washington University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Light therapy: a new hope for chronic pain sufferers?
Symptom relief TerminatedParticipants with chronic pain conditions including chronic low back pain and fibromyalgia may benefit from light stimuli presented to the retina to reduce chronic pain severity and pain sensitivity. Participants will be recruited into this study and will be presented with one of…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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AI matches doctors in spotting early vein disease
Diagnosis CompletedPurpose: To evaluate the sensitivity and specificity of the method for determining the clinical class of chronic venous diseases using the Ivenus application (within C0-C2 according to CEAP). Materials and methods: Patients who applied to several phlebology clinics for an initia…
Phase: NA • Sponsor: Clinic of Phlebology and Laser Surgery, Chelyabinsk, Russia • Aim: Diagnosis
Last updated Jun 27, 2026 09:10 UTC
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PET scans may reveal hidden leukemia spots before CAR t treatment
Knowledge-focused CompletedBackground Acute lymphoblastic leukemia (ALL) accounts for about 25 percent of childhood cancers and for about 20 percent of adult leukemias. The disease can be treated with CAR T-cell infusion but non-central nervous system (CNS) extramedullary disease (EMD) is associated with …
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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New app aims to keep kids with heart disease safe at home
Knowledge-focused ENROLLING_BY_INVITATIONThis is a multi-site research study with an optional research repository that will consist of clinically derived data and photographic or video images of patients in the home setting with complex health conditions to evaluate the safety and efficacy of the CHAMP® software platfor…
Sponsor: Lori Erickson • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Can family therapy tame teen aggression? new study says maybe
Knowledge-focused CompletedThe purpose of this study is to investigate the effectiveness and mediators of Forensic Outpatient Systemic Therapy (FAST).
Sponsor: Utrecht University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New study tracks hidden risks after tracheostomy tube removal
Knowledge-focused Recruiting nowThis longitudinal observational study involves an integrated knowledge translation (IKT) approach involving key stakeholders in the project team to evaluate the tracheostomy management in patients hospitalized in the Swiss Paraplegic Centre Nottwil (SPC).
Sponsor: Katharina Winiker • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Heart prep: 8-Week home workout may shield stem cell patients
Knowledge-focused Recruiting nowTo assess the feasibility and preliminary effectiveness of a Cardio-Oncology Prehabilitation program in patients at high-risk of developing Cardiovascular (CV) events in improving Cardiorespiratory fitness (CRF) and reducing acute CV complications in Hematopoietic stem cell trans…
Phase: NA • Sponsor: University of Michigan Rogel Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Ketone drink study reveals surprising effects on blood hormones
Knowledge-focused CompletedThis study aims to address two key aspects. First, the suitability of selecting a specific sampling site for BHB measurement in patients and research, as well as potential differences between capillary and venous blood measurements. Additionally, the study will investigate the ef…
Phase: NA • Sponsor: Central Jutland Regional Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Inflammation clues after heart attack could predict future risks
Knowledge-focused CompletedThe aim of this research is to study the prognostic role of a selected combination of cytokines and adipokines in patients with myocardial infarction, as well as to determine their role in the development of adverse cardiac remodeling.
Sponsor: Nicosia General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Alport patients needed: join a registry to speed up research
Knowledge-focused Recruiting nowAlport Syndrome Foundation's (ASF's) Alport Patient Registry (the Registry) is open to individuals living with Alport syndrome in the United States (US) and US territories and outlying islands. The Registry welcomes participants of all ages who have a confirmed clinical diagnosis…
Sponsor: Alport Syndrome Foundation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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New HIV shot candidates enter first human safety tests
Disease control OngoingThe primary purpose of the study is to investigate safety and tolerability following single and multiple ascending subcutaneous (SC) and intramuscular (IM) doses of capsid inhibitors in healthy participants. The study will also describe the pharmacokinetics following single and m…
Phase: PHASE1 • Sponsor: ViiV Healthcare • Aim: Disease control
Last updated Jun 26, 2026 14:10 UTC
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Teens who do good deeds may feel better, study finds
Symptom relief CompletedAdolescents will complete a 4-week intervention, during which they will either complete a kind act for others, complete a kind act for others with a reflection component, or report their daily activities three days per week. Psychological measures will be indexed before and after…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 26, 2026 14:00 UTC
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Brain zapping while thinking: a smarter way to boost your mind?
Knowledge-focused CompletedThe study will examine whether the benefits of brain stimulation on mental functioning can be enhanced if an individual is actively engaging the target brain networks while receiving brain stimulation. The study includes two separate sessions and people will complete either a cog…
Phase: PHASE4 • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Dialysis bicarbonate levels under scrutiny: can a simple change protect heart health?
Knowledge-focused Recruiting nowQTc prolongation and premature ventricular contractions (PVCs) are common in hemodialysis (HD) patients and are associated with sudden cardiac death. It is known that higher dialysate bicarbonate is associated with more QTc prolongation during HD sessions. This study aims to as…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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New device aims to make prostate biopsies more accurate
Diagnosis Recruiting nowThis study aims to assess the feasibility of magnetic resonance (MR) guided prostate biopsy using a needle holder frame. This frame is used to help position the needle used for the biopsy. The feasibility in this study is defined as whether the needle holder frame enables accurat…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 08:01 UTC
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New program aims to ease diabetes care transition for teens
Knowledge-focused OngoingThe purpose of this research study is to evaluate a transition preparation program designed for adolescents and young adults (AYAs) with type 1 diabetes (T1D). This transition program will support AYAs as they prepare to transition from pediatric to adult endocrinology medical ca…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Can a phone app explain why depression hits girls harder in puberty?
Knowledge-focused Recruiting nowStarting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention deficit hyperactivity disorder (ADHD). This divergen…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Green tea compound tested for lung scarring disease
Disease control CompletedThe primary purpose of this multi-center, double-blind, placebo-controlled, dose-ranging Phase I study is to assess the safety of a purified from green tea, EGCG, in patients with idiopathic pulmonary fibrosis (IPF) as a potential novel treatment for pulmonary fibrosis.
Phase: PHASE1 • Sponsor: Hal Chapman • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Glue or stitches? study finds which C-Section closure patients prefer
Symptom relief CompletedThe aim of this study is to compare cesarean incision outcomes between patients with incision closed with the Dermabond Prineo system compared to standard subcuticular suture.
Phase: NA • Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC