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116076 trials found · Page 4484 of 5804
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Psoriasis patients weigh in: is wynzora cream the new favorite?
Symptom relief CompletedThe primary objective is to assess with the PPQ questionnaire the patient preference for Wynzora compared with therapy carried out previously with Enstilar spray foam. Secondary objectives Assess satisfaction with the treatment. Assess adherence to therapy. Evaluate the impact of…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated Jun 26, 2026 12:55 UTC
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Brain health bootcamp: VA tests 20-Week program for aging veterans
Knowledge-focused OngoingThe purpose of this study is to learn about the effects of AgeWISE-Action Plan (AgeWISE-AP), a 20-week program designed to provide education and individualized planning with a goal of improving brain health.
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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ER timing could be key to saving heart attack victims
Knowledge-focused Recruiting nowThis study examines the impact of emergency department (ED) management on short-term outcomes of nontraumatic adult out-of-hospital cardiac arrest (OHCA) patients. Conducted by a research team at National Taiwan University Hospital and its affiliated hospitals, including branches…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Which sealer hurts less? 120 patients tested
Symptom relief CompletedThe objective of this research was to identify which of the root canal sealers, AH Plus or WellRootST, yielded more effective outcomes regarding postoperative pain when applied to teeth diagnosed with apical periodontitis.
Phase: NA • Sponsor: Medipol University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Laser showdown: which technique eases heel pain best?
Symptom relief CompletedThe objective of this randomized controlled clinical trial (RCT) with a double-blind technique and longitudinal chronology, is to evaluate and compare the effectiveness of High intensity laser therapy (HILT) in static mode versus scanning mode in the reduction of pain associated …
Phase: NA • Sponsor: University of Seville • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Sniffing geranium oil may ease chemo sickness
Symptom relief CompletedChemotherapy-induced nausea and vomiting (CINV) remain among the most distressing side effects experienced by cancer patients and can significantly affect treatment tolerance and quality of life. Geranium essential oil has been proposed as a complementary, non-pharmacological the…
Phase: NA • Sponsor: Universitas Muhammadiyah Surakarta • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Antibody clues after stem cell transplants could prevent rejection
Knowledge-focused CompletedDonor specific anti-HLA antibody (DSA) is closely related not only to primary graft rejection (GR) after HLA-incompatible transplantation, but also to the occurrence of primary PGF. Desensitisation therapy can reduce the level of DSA in patients and decrease the incidence of PGF …
Sponsor: Peking University People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New dental implant technique shows promise for bone loss patients
Disease control Recruiting nowThis retrospective study will evaluate the clinical performance of maxillary All-on-X(full-arch implant-supported rehabilitation) implant rehabilitation using stackable guided surgery and immediate loading. Implant survival and peri-implant outcomes will be assessed over a 2-year…
Sponsor: Menoufia University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Can a Self-Guided online course help parents and kids manage emotions?
Symptom relief CompletedThis study aims to evaluate the feasibility and acceptability of the eParenting CARE Program, an asynchronous, self-guided emotion-focused parenting intervention for parents of school-aged children (8-13 years). The eParenting CARE Program focuses on strengthening parent emotion …
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Does anesthesia flow affect brain pressure during surgery?
Knowledge-focused CompletedThis prospective randomized study was conducted to evaluate the effects of low-flow and high-flow anesthesia on intracranial dynamics and cerebral oxygenation in patients undergoing laparoscopic hysterectomy in the Trendelenburg position. Intracranial pressure was assessed noninv…
Sponsor: Bursa City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Hernia repair without general anesthesia: a game changer for frail patients?
Symptom relief CompletedPrimary midline hernias, including umbilical and epigastric hernias, are prevalent surgical conditions, necessitating intervention. The optimal choice of anesthesia for umbilical and epigastric hernia repair remains an area of uncertainty. This pilot study focuses on the manageme…
Phase: NA • Sponsor: Region Örebro County • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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New gluten challenge study aims to make 'Gluten-Free' labels safer
Knowledge-focused CompletedThe study will compare the immune response in CeD patients to wheat and barley gluten at high doses (1 gram), and also investigate the reponses to low dose barley gluten and also hydrolyzed, malted barley and placebo. This will be done by five one-day challenges with intervals ar…
Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Could a muscle relaxant suppository ease chronic pelvic pain?
Symptom relief CompletedThe purpose of this study is to evaluate if baclofen vaginal suppositories improve symptoms of Chronic Pelvic Pain (CPP). Participants in this study will take four short questionnaires prior to being randomized. Randomization is like flipping a coin; participants have an equal l…
Phase: PHASE2 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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ER tube study questions painful routine for blocked bowel
Knowledge-focused OngoingSmall bowel obstruction (SBO) occurs when the normal movements of the small bowel is obstructed, most commonly due to adhesion related to previous abdominal surgery. This may cause strangulation of the small bowel with reduced blood flow which is a surgical emergency requiring pr…
Sponsor: Daniel Wilhelms • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Massive study reveals Real-World impact of respiratory failure in china
Knowledge-focused CompletedWe aim to prospectively assess the burden, management and therapeutic approaches and outcomes of acute respiratory failure requiring respiratory support, during the winter months in China. The purpose of this study is to provide new and current data on the disease burden of acut…
Sponsor: Southeast University, China • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Brain scans probe Serotonin's role in Parkinson's pain
Knowledge-focused Recruiting nowThis project will explore the involvement of the serotonin system in the pathophysiology of PD-related central pain. Thus, the serotonin system will be evaluated in PD patients with and without central pain who will benefit from brain positron emission tomography (PET) allowing i…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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New app aims to make chemsex safer for gay men
Knowledge-focused CompletedThis study is examining the usability and effectiveness of an innovative mobile app that integrates harm reduction strategies into the existing pre-exposure prophylaxis (PrEP) intake and adherence app, with an overarching goal to reduce the potentially negative consequences of pr…
Phase: NA • Sponsor: National Cheng Kung University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Repeat CT scans after minor head injury: helpful or not?
Knowledge-focused OngoingRetrospective observational study on a cohort of 2 years to evaluate the incidence of brain hemorrhage present at control head CT scan executed after routine 24h observation period of ED stay in patients with minor head injury on anticoagulant therapy or DAPT with an initial nega…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Breath of life: CO2 readings may predict cardiac arrest survival
Knowledge-focused OngoingThe investigators aim to assess the relationship between patient characteristics, prehospital treatments, and vital signs to determine if a threshold EtCO2 value, a change in EtCO2 value (final - initial), or a trend in EtCO2 (positive/negative) is a better predictor of patient s…
Sponsor: Office of the Medical Director for EMS in Oklahoma City and Tulsa • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Are patients treated differently because of their ethnicity? new study digs into digital doctor visits
Knowledge-focused CompletedThe aim of this study is to examine whether patients are subjected to ethnic discrimination when seeking medical care within the digital Swedish primary health care service: 1177-direct. In doing so, we aim to identify and statistically control for other major pathways through wh…
Sponsor: Linnaeus University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC