Study aims to find safer radiation approach for rectal cancer surgery

NCT ID NCT07346248

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at 266 adults with advanced rectal cancer who had radiation therapy followed by surgery. It compares standard chemoradiotherapy or short-course radiotherapy with a newer approach called total neoadjuvant treatment (TNT). The goal is to see which method leads to fewer complications within 90 days after surgery, helping doctors choose the safest option.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors choose safer treatment plans for rectal cancer patients, reducing post-surgery complications.
What could go wrong
This is a retrospective study, meaning it looks back at past data, so it cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS Humanitas Research Hospital

    Rozzano, Milan, 20089, Italy

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