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127005 trials found · Page 4222 of 6351
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Buzz off, needle pain! new device could make dental shots a breeze for kids
Symptom relief Not yet recruitingThe goal of this clinical trial is to test if children aged between 6 and 14 years who are receiving a dental injection will feel less pain by using a vibration device applied to the injection site during the injection compared to vibrating the lip using only the researcher's han…
Sponsor: King Abdulaziz University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Which drug eases pain better after sleeve gastrectomy?
Symptom relief Recruiting nowAlthough laparoscopic (LAP) bariatric surgery is minimally invasive. Following any laparoscopic procedure, patients typically experience the peak of postoperative pain within the first 24 hours. This intense pain gradually subsides, with significant relief usually occurring by th…
Sponsor: Alexandria University • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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AI-Powered question lists could help blood cancer patients get more from doctor visits
Symptom relief Recruiting nowThe goal of this study is to evaluate the feasibility and preliminary efficacy of an artificial intelligence (AI)-generated personalized question prompt list (a list of suggested questions to ask during outpatient appointments) for patients with hematologic cancers. The intervent…
Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Hands-On breastfeeding class before delivery may stop painful nipples
Prevention Not yet recruitingSeveral studies show that breastfeeding problems in the first days of birth pose a significant obstacle to successful breastfeeding. Among the most common breast problems experienced by mothers are breast abscesses, mastitis, nipple pain and sore nipples, engorgement, and flat or…
Sponsor: Gadjah Mada University • Aim: Prevention
Last updated Jun 27, 2026 08:05 UTC
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Moms of ADHD kids face tougher fibromyalgia battle?
Knowledge-focused Recruiting nowIn this study, the investigators aimed to evaluate the impact of having a child diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) on parental disease burden in mothers diagnosed with Fibromyalgia Syndrome (FMS). The study will include 50 mothers with FMS who have a …
Sponsor: Sultan 1. Murat State Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New surgery aims to rebuild hips in children after severe infection
Disease control Not yet recruitingAbsence or loss of the growth plate together with the epiphysis of a long bone presents a very difficult condition to treat. An example of this is the loss of the head and neck of the femur especially as a part of severe sequelae of infantile septic arthritis.
Sponsor: Assiut University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Can ultrasound make intubation safer for acromegaly patients?
Knowledge-focused Not yet recruitingThis is a prospective observational study.The purpose of this study is to predict difficult intubation with ultrasonographic evaluation combined with preoperative physical examination in patients diagnosed with acromegaly and planned for pituitary surgery.
Sponsor: Başakşehir Çam & Sakura City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Gut bacteria could be key to stopping cancer Drug's diarrhea side effect
Knowledge-focused Recruiting nowBackground: Pyrotinib is an effective targeted drug for HER2-positive breast cancer, but it very frequently causes diarrhea, which can be severe enough to disrupt treatment and reduce patients' quality of life. The reason why some patients develop diarrhea while others do not is…
Sponsor: Hubei Cancer Hospital • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Eye surgery showdown: which needle spot works best for kids?
Disease control Not yet recruitingThis is a single-blind, single-center, parallel-group randomized controlled trial with the following objectives: First, researchers aim to compare the clinical efficacy of 2mm and 2.5mm post-limbal needle insertion in sutureless transscleral IOL fixation for patients with congeni…
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New study aims to make intubation safer for bariatric surgery patients
Knowledge-focused Recruiting nowThis study is designed as a prospective observational study and will be conducted at the Health Sciences University Antalya Training and Research Hospital. Adult patients scheduled to undergo bariatric surgery will be included. The aim of this study is to compare the El Ganzouri…
Sponsor: Antalya Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Simple Pre-Surgery breathing test may spot oxygen risk after Weight-Loss surgery
Knowledge-focused Not yet recruitingThis prospective observational study evaluates whether the preoperative ROX index can predict early postoperative hypoxemia in patients undergoing bariatric surgery. Preoperative ROX measurements, along with ARISCAT and STOP-Bang scores, will be assessed for their association wit…
Sponsor: Istinye University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Simple blood markers may predict whipple surgery complications
Knowledge-focused Not yet recruitingWhipple surgery is a complex abdominal procedure associated with a high risk of hemodynamic instability and splanchnic hypoperfusion leading to anastomotic leaks, delayed gastric emptying, and organ dysfunction Traditional markers (e.g., MAP, mixed venous oxygen saturation \[SvO₂…
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New study aims to find best pain relief for kids after kidney surgery
Symptom relief Not yet recruitingTo compare the efficacy and safety of ultrasound-guided ESPB versus QLB for post-operative analgesia in children undergoing kidney surgery.
Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Laughter yoga tested as a fun remedy for PMS
Symptom relief CompletedPremenstrual Syndrome (PMS) describes somatic, cognitive, emotional, and behavioral symptoms that occur in women during the luteal phase of the menstrual cycle and resolve with the onset of menstruation. These symptoms are common during the reproductive years. The emotional sympt…
Sponsor: Kırklareli University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Surgeons test High-Tech headset for better views in the operating room
Knowledge-focused Not yet recruitingThis study looks at how well the MyVeo surgical visualization headset works during routine surgeries. MyVeo is a wearable device that helps surgeons see the surgical area in high detail, including blood flow and tissue fluorescence, without needing to look through a traditional m…
Sponsor: Leica Microsystems (Schweiz) AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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New program aims to boost mental toughness in Hearing-Impaired students
Knowledge-focused CompletedThe goal of this clinical trial (quasi-experimental study) is to learn whether an integrative therapeutic program can enhance psychological hardiness among hard-of-hearing (HOH) female students in Saudi Arabia (Al-Ahsa Governorate). The main questions it aims to answer are: 1. W…
Sponsor: King Faisal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New drug targets hidden pain after keyhole surgery
Symptom relief Stopped earlyVisceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes. Effective visceral pain management should constitute an essential component of postoperative analgesic strategies following laparoscopic procedures. H…
Phase 4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Which anesthesia gets you home faster after vein surgery?
Symptom relief CompletedVaricose veins represent irreversible, abnormal dilatations of the venous structures. They manifest as tortuous, swollen vessels visible beneath the skin of the lower extremities, particularly the feet and legs. Symptoms typically worsen with prolonged standing or sitting. In the…
Sponsor: Ankara Etlik City Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Pregnancy skin care: experts agree on What's safe
Knowledge-focused By invitation onlyThis research presents a comprehensive consensus on pregnancy skin care, synthesizing expert recommendations to ensure maternal skin health while prioritizing fetal safety. It outlines safe and effective skin care practices tailored to the physiological and hormonal changes durin…
Sponsor: Venus Research Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Ozone gel plus sound waves could soothe stubborn shoulder pain
Symptom relief Not yet recruitingThis study will be conducted to investigate the effect of ozonated gel phonophoresis on pain intensity, shoulder joint range of motion, and functional disability in patients with chronic supraspinatus tendinitis grades I and II.
Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC