Gut bacteria could be key to stopping cancer Drug's diarrhea side effect

NCT ID NCT07264985

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at why some breast cancer patients get diarrhea from the drug pyrotinib while others don't. Researchers will compare the gut bacteria of 60 patients who develop diarrhea with those who don't. They hope to find specific bacteria that protect against this side effect, which could lead to better ways to manage it in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pyrotinib

What this could lead to

If successful, this could point toward ways to predict or prevent severe diarrhea in breast cancer patients taking pyrotinib.

What could go wrong

This is a small, early observational study with no treatment being tested. It may not find clear links, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm diarrheal disease Drug-Related Side Effects and Adverse Reactions HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hubei Cancer Hospital

    Wuhan, Hubei, 430079, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••