Gut bacteria could be key to stopping cancer Drug's diarrhea side effect

NCT ID NCT07264985

First seen Jun 25, 2026 · Last updated Jul 17, 2026 · Updated 4 times

Summary

This study looks at why some breast cancer patients get diarrhea from the drug pyrotinib while others don't. Researchers will compare the gut bacteria of 60 patients who develop diarrhea with those who don't. They hope to find specific bacteria that protect against this side effect, which could lead to better ways to manage it in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pyrotinib
What this could lead to
If successful, this could point toward ways to predict or prevent severe diarrhea in breast cancer patients taking pyrotinib.
What could go wrong
This is a small, early observational study with no treatment being tested. It may not find clear links, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hubei Cancer Hospital

    RECRUITING

    Wuhan, Hubei, 430079, China

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