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116076 trials found · Page 4180 of 5804
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Semaglutide's heart benefits explored in new study
Knowledge-focused CompletedThe goal of this observational study is to learn about the effects of semaglutide to coronary artery flow in diabetic and non-diabetic patients. The main question it aims to answer is: Does semaglutide enhance coronary artery flow in diabetic and non-diabetic patients? Particip…
Sponsor: Ekrem Bilal Karaayvaz • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Scabies cure rates under the microscope: national study reveals treatment success
Knowledge-focused CompletedMulticentre retrospective, prospective, non-profit, national observational study
Sponsor: Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Iron therapy showdown: daily vs. Alternate-Day for anemic kids
Disease control CompletedTreating iron deficiency anemia in children with daily and alternate day oral iron therapy
Phase: PHASE3 • Sponsor: University of Child Health Sciences and Children's Hospital, Lahore • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New light device could replace invasive fluid monitoring in ICUs
Knowledge-focused Recruiting nowProof-of-concept observational study including ICU patients undergoing a PLR maneuver. Local microvasculature will be assessed with the hDOS platform on the brachioradialis muscle, deriving the microvascular blood flow index (BFI) and tissue oxygen saturation (StO2). CO will be a…
Sponsor: Corporacion Parc Tauli • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New C-Section pain protocol shows promise in reducing severe pain
Symptom relief CompletedInadequate pain relief remains a challenge after Cesarean section (CS) and may significantly impair postoperative recovery. A recent Danish single-center study (n=100) revealed that 66% of elective CS patients experienced severe pain (NRS ≥ 7) during the first 24 hours, with the …
Sponsor: Nordsjaellands Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Heart failure patients get a digital boost: video education trial launches
Knowledge-focused ENROLLING_BY_INVITATIONBackground: Heart Failure (HF) is one of the most prevalent pathologies in Western countries, representing a significant percentage of their healthcare expenditure. Much of the success of specialised programmes for the control and treatment of this pathology is achieved within He…
Phase: NA • Sponsor: Maria Jose Santi Cano • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Gut hormone GLP-1 may influence bone strength, new study finds
Knowledge-focused CompletedBone is a dynamic organ that is remodelled throughout life by a coupled process of resorption and formation of bone tissue, which are highly energy-demanding processes. Bone remodelling is tightly regulated by several endocrine factors such as parathyroid hormone, sex steroids in…
Phase: NA • Sponsor: Odense University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New study digs into brain fog and social struggles in mood disorders
Knowledge-focused Recruiting nowBipolar disorder (BD) are common psychiatric disorders often misdiagnosed, leading to delayed treatment. Even during stable phases, individuals with bipolar disorder experience residual cognitive impairments that affect their social functioning and quality of life. This study ai…
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Could a ketone drink boost CAR-T success in lymphoma?
Disease control Recruiting nowThe aim of this study is to assess the feasibility of β-hydroxybutyrate (BHB) supplementation in individuals who are receiving therapy for lymphoma with standard-of-care anti-CD19 CAR T-cells (CAR-T) to determine whether BHB supplementation is safe and tolerable in this patient p…
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Brain scans reveal how positive thinking may change choices in schizophrenia
Knowledge-focused Recruiting nowThe goal of this clinical trial is to learn if attention and ways of thinking impact decision-making and brain processes related to decision-making in people with schizophrenia or schizoaffective disorder relative to people without either condition. It will also learn how brain f…
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Fitbits could spot infections in kids after surgery
Knowledge-focused Recruiting nowThe purpose of this study is to analyze Fitbit data to predict infection after surgery for complicated appendicitis and the effect this prediction has on clinician decision making.
Phase: NA • Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Firefighters at risk: study reveals heat stress weakens balance and strength
Knowledge-focused CompletedThis study will examine the effect of heat stress on factors that influence musculoskeletal injury risk in firefighters. Participants will attend 4 data collection sessions. 1: informed consent, screening, and familiarization. 2: pre-tests (strength, balance, and movement quality…
Phase: NA • Sponsor: Louisiana State University Health Sciences Center Shreveport • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Mouth guard eases pain after gum graft, study finds
Symptom relief CompletedEpithelialized gingival graft (EGG) harvesting from the palate is associated with postoperative morbidity, including pain and bleeding, due to healing by secondary intention. The effectiveness of palatal stents in reducing donor-site morbidity, particularly in suture-free techniq…
Phase: NA • Sponsor: University of Turin, Italy • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Patient voices shape better anesthesia for emergency C-Sections
Knowledge-focused CompletedThis study aims to explore the patients' and providers' perspectives and inform future anesthetic practice for patients undergoing unexpected cesarean delivery (CD) under neuraxial anesthesia (NA). The consideration of patients' concerns, preferences, expectations, and suggestion…
Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New hope for back pain sufferers: no surgery needed?
Symptom relief OngoingThis project will determine the clinical utility of non-surgical spine decompression for chronic low back pain (LBP). LBP is one of the highest incidence medical conditions that contributes to disability, decreased activities of daily living, decreased quality of life, and inabil…
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Skin cancer surgery pain showdown: four numbing drugs compared in major trial
Symptom relief ENROLLING_BY_INVITATIONTo compare several local anesthetics when used during dermatological surgery.
Phase: PHASE4 • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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New therapy program shows promise in reducing suicide risk for dementia caregivers
Symptom relief CompletedThis project aims to adapt, implement, and evaluate a Dialectical Behavior Therapy skills training group intervention for aging adult family caregivers of person with Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) to reduce suicidality. By adapting this m…
Phase: NA • Sponsor: Texas Tech University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Sleep lessons may soothe diabetic nerve pain in small trial
Symptom relief CompletedThis randomized controlled study was designed to the effect of sleep hygiene education on sleep quality and quality of life in patients with painful diabetic polyneuropathy The study was conducted between January 2025 and January 2026 with 24 patients diagnosed with painful diabe…
Phase: NA • Sponsor: Trakya University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Chilly workouts may alter what you eat, small study suggests
Knowledge-focused CompletedThis study investigated whether exercising in cold environments affects appetite, energy intake, and food preference compared with exercising in thermoneutral conditions. Eleven healthy males completed five laboratory trials as part of a crossover study: a control trial and four …
Phase: NA • Sponsor: Coventry University • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Diabetes Drug's hidden effects on body fuel production revealed
Knowledge-focused Recruiting nowIn this study, PI will test the hypothesis that distinct mechanisms account for the SGLT2i-induced stimulation of ketogenesis and lipolysis versus endogenous (hepatic) glucose production in patients with type 2 diabetes (T2D) that the increases in ketone production and lipolysis …
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC