Could a blood clot replace gum surgery for dental implants?

NCT ID NCT07649239

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two methods to improve gum thickness around dental implants in the front of the mouth. One method uses a platelet-rich fibrin (PRF) membrane made from the patient's own blood, while the other uses a standard connective tissue graft. The trial will enroll 26 adults with a single missing tooth in the esthetic zone and measure gum thickness, bone loss, and patient satisfaction. If PRF works well, it could offer a less invasive option with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Platelet-rich fibrin (PRF) membrane

What this could lead to

If it works, this could offer a simpler, less painful way to improve gum thickness around dental implants, especially in visible front teeth.

What could go wrong

This is a small, early-stage trial with only 26 participants, so results may not apply to everyone. PRF may not be as effective as the standard graft for long-term gum stability.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

connective tissue disorder soft tissue neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gulf Medical University

    RECRUITING

    Ajman, Ajman Emirate, 00000, United Arab Emirates

    Contact Phone: •••-•••-•••• Email: •••••@•••••