Braces pain relief: which gel heals mouth ulcers faster?

NCT ID NCT07709455

Completed Symptom relief Sponsor: Dow University of Health Sciences Source: ClinicalTrials.gov ↗

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This trial tests whether hyaluronic acid gel or chlorhexidine gel works better for painful mouth ulcers that often appear after getting braces. Thirty people with braces who develop an ulcer will apply one of the gels three times daily for a week. Researchers will measure pain levels and ulcer size at the start, after three days, and after seven days to see which gel provides faster relief and healing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hyaluronic acid gel or chlorhexidine gel applied topically to mouth ulcers
What this could lead to: If one gel works better, it could offer a more effective way to ease pain and speed healing of braces-related mouth sores.
What could go wrong: This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. Both treatments are already used, so no major breakthrough is expected.

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Conditions

The condition(s) this trial relates to.

Oral Ulcer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORAL MUCOSAL ULCERATION ORTHODONTIC APPLIANCES, FIXED ORTHODONTIC TREATMENT TRAUMATIC ORAL ULCERATION

Contacts and locations

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Locations

Dow University of Health Sciences (DUHS)

Karachi, Pakistan

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