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116076 trials found · Page 3853 of 5804
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Is 'Watch and Wait' really 'Worry and Wait'? new study investigates
Knowledge-focused ENROLLING_BY_INVITATIONIndolent lymphomas, including chronic lymphocytic leukemia/small lymphocytic lymphoma, marginal zone lymphoma, low-grade follicular lymphoma, and Waldenström macroglobulinemia, are slow-growing cancers often managed initially with a watchful waiting strategy. This approach avoids…
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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ICU antibiotic dosing under the microscope: new study targets dialysis clearance
Knowledge-focused Not yet recruitingSevere bacterial infections, often responsible for sepsis and septic shock, are a major challenge in critical care: approximately 50% of patients are affected, with a mortality rate of up to 40%. Their initial management consists of antibiotic therapy with an adapted spectrum of …
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:48 UTC
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New device may cut opioid use after Open-Heart surgery
Symptom relief ENROLLING_BY_INVITATIONThis is a retrospective study based on analysis real world data obtained from hospitals that have adopted use of Montage or Montage-CT for use following sternotomy. The analysis will report the post-operative use of analgesic medication (including opioids) and compare the use aga…
Sponsor: Abyrx, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Could weak muscles mean higher bleeding risk for seniors on blood thinners?
Knowledge-focused Not yet recruitingThis study aims to assess whether reduced muscle mass is associated with an increased risk of bleeding in the elderly receiving direct oral anticoagulant therapy. The researchers will compare the muscle mass of patients who experienced a hemorrhage (case) with that of patients w…
Phase: NA • Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:19 UTC
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New study aims to sharpen dengue diagnosis
Diagnosis Not yet recruitingThe objective of this study is to collect well-characterized serum and plasma specimens from confirmed dengue positive and dengue negative subjects to support dengue diagnostic products development.
Sponsor: Abbott Rapid Dx • Aim: Diagnosis
Last updated Jun 27, 2026 07:52 UTC
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Can a simple ultrasound reveal hidden gut damage in scleroderma?
Knowledge-focused Not yet recruiting* Evaluation of splanchnic vasculature, including arterial blood flow using Doppler ultrasound in patients with systemic sclerosis compared to healthy subjects. * Correlation of Doppler findings of splanchnic vessels with GIT manifestations. * Correlation of Doppler findings of s…
Sponsor: Esraa Moustafa Mohammed • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:33 UTC
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New study aims to ease back pain from spinal anesthesia
Symptom relief Recruiting nowThis study will evaluate whether giving sedation before spinal anesthesia, when performed with ultrasound guidance, reduces the risk of developing back pain after surgery. Spinal anesthesia is commonly used but may cause discomfort or persistent back pain in some patients. By com…
Phase: NA • Sponsor: Benha University • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Shock and stretch: new combo therapy aims to fix old ankle injuries
Symptom relief Recruiting nowAnkle sprains are one of the most common sports injuries. In some people, they can lead to chronic ankle problems that affect daily life and sports performance. In this study, we want to see if combining neuromuscular electrical stimulation (NMES) with proprioceptive neuromuscula…
Phase: NA • Sponsor: Fooyin University • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Dental showdown: which pulp treatment works best for kids?
Disease control Not yet recruitingThis randomized clinical trial aims to evaluation the clinical and radiographic outcomes of hyaluronic acid, TheraCal, and Mineral Trioxide Aggregate (MTA) when used as pulpotomy agents in primary molars. The main question it aims to answer is: In children with restorable mandi…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 26, 2026 15:37 UTC
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ICU survivors: new study tracks lingering health problems years later
Knowledge-focused Not yet recruitingIntensive Care Units (ICU) stabilize and maintain vital functions in critically ill patients, optimizing their survival. However, patients with prolonged stays may develop Post-ICU syndrome , characterized by physical, cognitive and psychological dysfunctions. This syndrome consi…
Sponsor: Dr. Negrin University Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:02 UTC
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New study to check how well bronchoscopy works for kids who inhale objects
Knowledge-focused Not yet recruitingOutcome of Bronchoscopy in Pediatric patient with foreign body aspiration
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:47 UTC
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Which sedative is kinder to the aging brain after surgery?
Symptom relief Recruiting nowThis study aims to compare two medications, Remimazolam and Midazolam, used for sedation during orthopedic surgeries performed under regional anesthesia. We want to find out which medication provides better sedation during the procedure and which one affects early recovery of bra…
Phase: PHASE3 • Sponsor: Romanian Society for Enteral and Parenteral Nutrition • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Superbug risk in preterm pregnancy: new study seeks answers
Knowledge-focused Not yet recruitingThis study looks at how common certain antibiotic-resistant bacteria (called extended-spectrum beta-lactamase-producing Enterobacteriaceae, or E-BLSE) are in pregnant women who experience premature breaking of their water before full term. The goal is to understand how often thes…
Sponsor: Centre Hospitalier de Saint-Denis • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Ultrasound of tiny fetal vein may spot troubled pregnancies early
Knowledge-focused Not yet recruitingThis observational study investigates whether blood flow in the ductus venosus, a small fetal vein measured by Doppler ultrasound, is related to pregnancy outcomes. A total of pregnant women with and without intrauterine growth restriction (IUGR) will be examined between 24 and 3…
Sponsor: Izmir City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Cord blood cells aim to heal Radiation-Damaged lungs
Disease control Not yet recruitingThis study aims to evaluate the safety and efficacy of the umbilical cord blood mononuclear cells (UCB-MNCs) therapy for radiation-induced lung injuryr (RILI) by observing factors related to the therapeutic effect and adverse reactions of UCB-MNCs in treating RILI .
Phase: EARLY_PHASE1 • Sponsor: Zhejiang Cancer Hospital • Aim: Disease control
Last updated Jun 26, 2026 18:20 UTC
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Small study aims to speed up sepsis diagnosis
Knowledge-focused Recruiting nowBlood culture (BC) is the gold standard for the definitive diagnosis of bacteraemia, providing the opportunity to recover and identify the causative organism, and optimize subsequent antimicrobial treatment. Detection of bacteraemia is critical for the management of sepsis. This …
Sponsor: Gloucestershire Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Can mapping skills cut burnout in baby units?
Knowledge-focused OngoingIn neonatal care, patient safety depends not only on individual clinical skills, but also on how teams recognize and use the competencies available during a shift. When staff are uncertain about who is able to perform specific tasks, coordination can become difficult, and respons…
Phase: NA • Sponsor: University of Aarhus • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Bleach strength during root canal retreatment may affect pain, study finds
Knowledge-focused Recruiting nowThis randomized clinical study aims to evaluate the effect of different sodium hypochlorite concentrations (1%, 2.5%, and 5.25%) used during root canal retreatment on intracanal levels of Substance P, CGRP, and Opiorphin, as well as postoperative pain. Patients requiring non-sur…
Phase: NA • Sponsor: KEZBAN MELTEM ÇOLAK • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Can simple shoulder exercises help new moms breastfeed better?
Symptom relief Recruiting nowThis study aims to compare the effects of scapular posterior tilt exercises and cross-body stretching on breastfeeding efficiency, latch quality, and posture in postpartum women with rounded shoulders.
Phase: NA • Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Can a different rinse cut pain after root treatment in kids?
Symptom relief CompletedThis randomized clinical trial evaluated the effect of two different irrigation solutions on postoperative pain following regenerative endodontic treatment of necrotic immature permanent teeth with apical periodontitis. Participants were randomly allocated to receive either 0.1% …
Phase: NA • Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated Jul 25, 2026 00:00 UTC