Anesthesia choice may affect immune system during breast cancer surgery

NCT ID NCT07648810

Not yet recruiting Knowledge-focused Sponsor: Clinical Hospital Center Rijeka Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will enroll 56 women with breast cancer to see if two different regional anesthesia techniques (paravertebral block vs. erector spinae plane block) cause different immune responses during surgery. Participants will receive one of the two blocks along with general anesthesia using propofol. Blood samples will be taken before surgery and at 24 and 48 hours after to measure immune markers. The goal is to find which method may be less disruptive to the immune system.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: regional anesthetic injection (paravertebral block or erector spinae plane block) with propofol general anesthesia
What this could lead to: If it works, this could help doctors choose an anesthesia method that causes less immune disruption during breast cancer surgery.
What could go wrong: This is a small, early-stage study (56 participants) that only measures immune markers, not long-term outcomes. Results may not change practice or apply to all patients.

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Conditions

The condition(s) this trial relates to.

breast cancer female breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER FEMALE

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