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127005 trials found · Page 3794 of 6351
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C-Section skin closure showdown: staples may beat stitches
Symptom relief Not yet recruitingDespite the high numbers of cesareans being performed, scientific evidence behind which surgical techniques are best remains uncertain. Our objective is to determine if subcuticular absorbable staples improve operative time and wound cosmetics
Sponsor: Inova Health Care Services • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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New needle angle could mean less back pain for millions
Symptom relief Not yet recruitingThe purpose of this voluntary research study is to determine whether the parasagittal approach to lumbar medial branch (LMB) nerve radio frequency ablation (RFA) will have greater efficacy than the traditional approach to lumbar medial branch nerve radio frequency ablation.
Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jul 25, 2026 00:00 UTC
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New tool aims to close STEM gap for black students
Knowledge-focused Not yet recruitingBlack students experience significant achievement gaps that contribute to underrepresentation in high paying STEM fields and disparity in health and economic outcomes. Effective middle-school interventions include exposure to culturally relevant STEM role models, instruction in a…
Sponsor: Oregon Research Behavioral Intervention Strategies, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New catheter study aims to ease bathroom struggles for millions
Symptom relief Not yet recruitingThis clinical investigation is a post-market, exploratory, randomised, parallel, open-label investigation comparing two UKCA/CE-marked transanal irrigation products for the management of faecal incontinence and/or chronic constipation of heterogenous origin. The aim of this inves…
Sponsor: Qufora A/S • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Can home tests replace lab draws for rare disease patients?
Diagnosis Recruiting nowThe goal of this study is to determine if the Lactate Plus meter is accurate compared to lab lactate levels, and to determine if the Accu chek guide glucometer is accurate compared to lab serum glucose levels in patients with Glycogen Storage Disease Types Ia, Ib and XI. To dete…
Sponsor: Connecticut Children's Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 13:01 UTC
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See yourself slimmer: 3D avatars may change how we think about weight loss
Knowledge-focused Not yet recruitingThe goal of this observational survey pilot study is to learn how 3D visualization tools (i.e., personalized avatars) influence weight loss goals, satisfaction, confidence, and commitment compared to numerical weight outcomes in weight loss-seeking adults. The main questions it …
Sponsor: Pennington Biomedical Research Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Can a short stint in a knee brace boost recovery after revision knee surgery?
Symptom relief Recruiting nowThe goal of this study is to evaluate if knee immobilization for 10 days following revision total knee arthroplasty (rTKA) improves knee joint range of motion at 3 months postoperatively compared to standard of care postoperative protocol. Participants will be assigned to one of…
Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Aug 26, 2026 00:00 UTC
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Simple surgical trick may cut repeat brain surgery in older adults
Disease control Recruiting nowChronic subdural haematoma (cSDH) is a common condition in older adults, usually treated by burr-hole surgery to drain the collection. Even with good surgery, around 1 in 10 patients develop a recurrence and need a second operation. Research shows that the outer lining of the hae…
Sponsor: University College, London • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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Paramedics test handheld ultrasound to spot heart failure in the field
Diagnosis Not yet recruitingThe goal of this prospective nonrandomized study is to determine if prehospital lung ultrasound findings result in a change in patient management. This study will look at how lung ultrasound exam improves diagnosis of respiratory distress in patients being treated by Emergency Me…
Sponsor: Rutgers, The State University of New Jersey • Aim: Diagnosis
Last updated Jul 15, 2026 00:00 UTC
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New study tests mindfulness breathing for chronic cough relief
Symptom relief Not yet recruitingThis study is a prospective, single-center, single-arm pilot trial. The primary research question is whether brief, breath control-focused Acceptance and Commitment Therapy (ACT) is feasible, acceptable, and safe in adults with chronic cough.
Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Heart and lung rehab under the microscope: what really works?
Knowledge-focused Not yet recruitingAim The aim of this project is to investigate the level of participation, satisfaction, changes in tests, and factors associated with these results in existing rehabilitation programmes at North Zealand Hospital and in the surrounding municipalities among patients with heart dise…
Sponsor: Nordsjaellands Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Computer alerts may boost life-saving prescriptions for kidney patients
Knowledge-focused Not yet recruitingThe goal of this pragmatic randomized clinical trial is to determine whether an Epic-based clinician notification increases initiation of guideline-directed cardio-kidney-metabolic (CKM) therapies in adults with type 2 diabetes and confirmed albuminuria. The main question it aim…
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Timing of anxiety drug may ease stress in Kids' surgery
Symptom relief Not yet recruitingThis study is a prospective, randomized, controlled clinical trial designed to evaluate the optimal timing of midazolam administration in children undergoing adenotonsillectomy. The study will be conducted at the Departments of Otorhinolaryngology and Anesthesiology of Erzurum Ci…
Sponsor: Erzurum City Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Almond butter may boost Kids' gut health, new study hopes to prove
Knowledge-focused Recruiting nowThis 8-week parallel-arm randomized controlled trial (N=70; ages 6-13) will determine the impact of daily almond butter consumption on gut microbiome composition and function, intestinal barrier integrity, and cardiometabolic health in school-aged children. Participants will be r…
Sponsor: Florida State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Diet coaching for gestational diabetes: a closer look at what works
Disease control Not yet recruitingThis study will evaluate the relationship between structured nutrition counseling, diet quality, and advanced glycation end products in pregnant women with gestational diabetes mellitus and women with normal glucose tolerance. Participants will be assigned to either a structured …
Sponsor: Istanbul Saglik Bilimleri University • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Gallstone surgery study: does ERCP access lower risks?
Knowledge-focused Not yet recruitingThe aim of this retrospective, register-based study is to investigate whether access, or no access, to endoscopic retrograde cholangiopancreatography (ERCP) at a surgical unit is associated with the risk of complications in patients undergoing laparoscopic cholecystectomy with co…
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New BP monitor could make life easier for heart pump patients
Knowledge-focused Not yet recruitingProspective, single-arm feasibility study will evaluate the use of an ultraslow deflation automated sphygmomanometer (Terumo Elemano 2) for home BP monitoring in patients with continuous-flow LVADs. Outcomes include patient-reported ability to obtain BP readings, adherence, ease …
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Video training for PEG tube caregivers may cut stress and boost skills
Symptom relief Not yet recruitingBackground: Percutaneous endoscopic gastrostomy (PEG) is used for patients who cannot be fed orally, have a reduced swallowing reflex, or require long-term feeding. PEG care and feeding, which is performed with nursing support in healthcare institutions, becomes the responsibilit…
Sponsor: Duzce University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Could a 12-Week lifestyle program ease chronic pain without drugs?
Symptom relief Not yet recruitingThis single-center, single-arm pilot feasibility study aims to examine the feasibility and preliminary effectiveness of an intervention program using a pain education booklet based on a multimodal lifestyle approach for patients with chronic pain with features of nociplastic pain…
Sponsor: Prefectural University of Hiroshima • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Ultrasound could guide emergency bleeding control
Knowledge-focused Not yet recruitingAs point-of-care ultrasound (POCUS) is becoming more available in the prehospital setting, it can be potentially used for more accurate and directed pressure application, thanks to its ability to image the artery and the underlying bony surface. The investigators therefore aim to…
Sponsor: Tel-Aviv Sourasky Medical Center • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC