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116076 trials found · Page 3584 of 5804
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Can a smartphone app help tame opioid addiction and chronic pain?
Symptom relief Recruiting nowThe goal of this clinical trial is to evaluate whether a smartphone app-based ecological momentary intervention called Mindful Journey, which teaches mindfulness skills, can support adults in recovery from both opioid use disorder and chronic pain. The primary objective of this p…
Phase: NA • Sponsor: Arizona State University • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Shock therapy for knees? device aims to rebuild muscle after ACL repair
Symptom relief ENROLLING_BY_INVITATIONThis study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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One session could boost exercise in IBD patients
Symptom relief Recruiting nowChronic inflammatory bowel diseases (IBD; including Crohn's disease and ulcerative colitis) significantly impact patients' quality of life. Among non-pharmacological therapies, adapted physical activity (APA) has demonstrated its beneficial impact, particularly on fatigue, anxiet…
Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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IVF incubator showdown: dry vs humidified – which grows better embryos?
Knowledge-focused Recruiting nowIVF incubators are essential for maintaining the micro-environment required for embryo development. Incubator technology has progressed from early humidified box systems to benchtop and now time-lapse platforms, driving the development of dry incubator chambers. Both humidified a…
Phase: NA • Sponsor: ART Fertility Clinics LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Bicarbonate levels may flag ICU risk in ER patients
Knowledge-focused Recruiting nowStatistical Association Between Bicarbonate Levels and Death or Admission to Intensive Care Within 48 Hours in Patients Presenting to the Emergency Department
Sponsor: Centre Hospitalier Departemental Vendee • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Microscope may ease tooth pain after deep cavity treatment
Symptom relief Not yet recruitingThe goal of this \[randomized clinical trials\] is to investigate the effect of using dental operating microscope incorperated in full pulpotomy procedure in mature carious posterior teeth. The main questions it aims to answer are: investigate postoperative pain levels. invest…
Phase: EARLY_PHASE1 • Sponsor: Chulalongkorn University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Desk makeover may ease aches for computer workers
Symptom relief CompletedThis study evaluates a workstation ergonomics program at Al-Baha University aimed at reducing work-related musculoskeletal symptoms among university employees who use computers regularly. The program includes an ergonomics self-assessment of the workstation, individualized guidan…
Phase: NA • Sponsor: Al-Baha University • Aim: Symptom relief
Last updated Jul 10, 2026 00:00 UTC
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Heart study pinpoints the moment angina strikes
Knowledge-focused Recruiting nowORBITA-SOLAR is an invasive physiological cardiac catheterisation study that aims to determine whether different coronary stenoses have different angina thresholds. The angina threshold is defined as the amount of coronary flow reduction required to reproduce symptoms. Sixty pati…
Phase: NA • Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Teen tennis stars: does training frequency boost explosive power?
Knowledge-focused CompletedAdolescence is a period characterized by rapid growth and development, characterized by intense structural, functional, and neuromuscular changes in the musculoskeletal system. The rapid height growth and proportional changes that occur during this period can negatively impact at…
Phase: NA • Sponsor: Biruni University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Parkinson's drug may impact gum disease risk
Knowledge-focused OngoingThe aim of this study is to evaluate the effects of Levodopa-Benserazide drug combination on periodontal status and salivary cytokine levels in patients with Parkinson's disease. The study includes four groups: Parkinson's patients with periodontitis, periodontally healthy Parkin…
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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New study aims to make cancer injections less painful with simple tricks
Symptom relief Not yet recruitingThis randomized controlled study will compare the effects of the ShotBlocker device and the Helfer Skin Tap Technique on pain and fear during intramuscular hormone injections in premenopausal and postmenopausal breast cancer patients. Ninety-nine participants will be randomly ass…
Phase: NA • Sponsor: Inonu University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Brain wave study aims to make anesthesia safer and more precise
Knowledge-focused Recruiting nowThis prospective observational study is designed to investigate and compare the dynamic features of whole-brain electroencephalogram (EEG) during the induction of unconsciousness using various anesthetic agents with distinct pharmacological mechanisms. The primary objective is to…
Sponsor: Huazhong University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Gut leak study seeks clues in lactose intolerant adults
Knowledge-focused ENROLLING_BY_INVITATION"This study evaluates the interplay between lactose intolerance, intestinal barrier function (zonulin), and intestinal inflammation (fecal calprotectin) in adults, aiming to clarify their independent contributions to symptom severity and quality of life."
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New study aims to objectively measure internal tremors in Parkinson's patients
Knowledge-focused Recruiting nowThe goal of the present study is to objectively access the presence of an Internal Tremor in Parkinson's disease. Inertial sensors will be used to detect the presence of a rhythmic oscillation of 3-4 Hz. The study will be performed in both Parkinson's disease patients and healthy…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Writing away the urge: new study tests 20-Minute exercise to curb binge drinking
Knowledge-focused ENROLLING_BY_INVITATIONThe purpose of the proposed research is to evaluate (1) whether a future possible self task (FPST) can lead to changes drinking identity (DI; how much one associates one's self with drinking) and (2) whether the FPST and changes in drinking identity also change indicators of alco…
Phase: NA • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Smartphone app aims to prevent diabetic foot problems
Symptom relief OngoingDiabetes mellitus is a metabolic disease with systemic, acute and chronic complications whose prevalence is increasing all over the world and in our country (Satman et al. 2013). The prevalence of diabetes all over the world and in Turkey is increasing day by day and this situati…
Phase: NA • Sponsor: Selma Sahin • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Scientists probe bone marrow cells to unravel waldenström macroglobulinemia
Knowledge-focused Recruiting nowWaldenström disease (WM) is defined by the presence of bone marrow lymphoplasmocytes and monoclonal immunoglobulin M (IgM). Treatment should be initiated in cases of cytopenia, tumor syndrome or when the physicochemical or immunological properties of IgM explain the occurrence of…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Exercise may boost metabolism in aggressive breast cancer patients
Knowledge-focused OngoingCancer is considered a major global public health problem. It was estimated that in 2022 approximately 19.9 million new cancer cases were diagnosed worldwide, and this number is expected to increase over the next two decades to 28.0 million (1). Specifically, breast cancer (BC) r…
Phase: NA • Sponsor: Universidad Europea de Madrid • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:04 UTC
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Smart rooms watch over cancer patients to prevent falls and confusion
Knowledge-focused Recruiting nowThis study uses ambient sensing rooms to collect data from hospitalized cancer patients in order to improve safety and recovery. Being hospitalized increases the risk for delirium (acute confusion), falls, troubles sleeping, and mood changes. Ambient sensing rooms are special roo…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Blood plasma may boost sperm survival after freezing
Knowledge-focused Recruiting nowSperm cryopreservation allows the preservation of sperm biological function for long periods of time for later use in assisted reproductive techniques (ART). However, the freezing and thawing process causes structural and functional damage to sperm, leading to decreased motility …
Sponsor: Instituto Valenciano de Infertilidad, IVI Alicante • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC