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Back pain breakthrough? steroid shots may offer relief without surgery

NCT ID NCT07538765

Symptom relief Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at whether steroid injections into the spine can reduce pain and improve daily function in people with lower back and leg pain from a herniated disc. 221 adults who had not improved with other treatments received the injections and were followed for three months. Researchers measured pain levels and ability to do everyday activities to see if the procedure works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
corticosteroid (steroid) injection
What this could lead to
If successful, this could confirm that steroid injections are a good option for managing back and leg pain without surgery.
What could go wrong
This is a retrospective study, not a controlled trial, so results may be less reliable. Pain relief may be temporary and not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

221 people

The number who actually took part.

Started

Sep 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

We included 252 patients admitted to unilateral or bilateral radiating pain in the lower extremity associated with Low Back Pain.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Between 18 and 90 years, * Presence of Low Back Pain with unilateral or bilateral pain radiating to the lower extremity, * Duration of symptoms for at least three months and unresponsive to conservative management, * Evidence of lumbar intervertebral disc herniation confirmed by MRI within the last six months Exclusion Criteria: * Prior lumbar ESI within 3 months, * History of polyneuropathy or entrapment neuropathy, * Presence of bleeding diathesis, * Systemic or local infections, * Having systemic and rheumatic diseases associated with peripheral nerve involvement.

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Conditions

The condition(s) this trial relates to.

lumbar disk herniation, susceptibility to radiculopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Radicular low back pain Transforaminal epidural steroid injection

Contacts and locations

Locations

  • Ankara City Hospital

    Ankara, Çankaya, 06800, Turkey (Türkiye)

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