Alzheimer's drug may tame annoying heart flutters
NCT ID NCT06501638
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether memantine, a drug currently used for Alzheimer's disease, can reduce the number of extra heartbeats (called premature atrial contractions or PACs) in people who have frequent and bothersome symptoms. 256 adults with at least 1000 extra beats per day took either memantine or a placebo for six weeks. Researchers measured changes in heart rhythm using a portable monitor to see if the drug helped.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Memantine hydrochloride (a drug used for Alzheimer's, repurposed here)
- What this could lead to
- If it works, this could offer a new treatment option for people with frequent, bothersome extra heartbeats.
- What could go wrong
- This is an early phase 2 trial, so results may not confirm effectiveness. Memantine can cause side effects like dizziness or confusion.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Shanghai East Hospital
Shanghai, Shanghai Municipality, 200120, China