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127005 trials found · Page 3253 of 6351
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Sesame oil spray may soothe sinus surgery recovery
Symptom relief CompletedThe goal of our thesis is to design, develop and characterize a novel thermodynamically stable NE by spontaneous method intended for topical use. Subsequently, appraisal of nanoemulsified sesame oil formulation has been performed on the post-operative symptoms in CRS patients who…
Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 26, 2026 15:34 UTC
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Can a natural brain chemical sharpen thinking in schizophrenia?
Symptom relief PausedSchizophrenia is a major public health problem associated with cognitive deficits, such as short and long term memory, executive functioning, attention and speed of processing that are amongst the strongest predictors of impaired functional outcome. In addition, schizophrenia pat…
Phase 1/2 • Sponsor: New York State Psychiatric Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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New drug may shorten jaundice in gallstone patients
Disease control CompletedObstructive jaundice is observed in 10-80 % of gallstone disease cases. The conventional tactics for the management of patients with obstructive jaundice is to remove biliary hypertension by using endoscopic or minimally invasive methods. The final surgical treatment is performed…
Sponsor: POLYSAN Scientific & Technological Pharmaceutical Company • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Sugar alcohol rinse could soothe sinus pain in cystic fibrosis
Symptom relief By invitation onlyCystic fibrosis (CF) is the most common genetic disorder in Belgium, affecting 1 in 2850 children. A defect in the CFTR channel results in increased viscosity of extracellular secretions and decreased mucociliary clearance in the airways. As a result of this mechanism, chronic rh…
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New hope for stroke patients: mouth training may restore swallowing
Symptom relief Recruiting nowThe aim of this study is to investigate the effect of a specific rehabilitation program with an oral device used in stroke patients with persistent oral-and pharyngeal dysphagia.
Sponsor: Umeå University • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Texts and tools could help liver transplant patients stay on track
Disease control OngoingLiver transplantation is increasingly performed for older adults with multiple comorbidities. Medication adherence is key to maintaining proper function of the transplanted liver and optimize health; however, adhering to post-transplant treatment is complex. This trial will study…
Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Salt caves may boost the power of yoga breathing for smokers' lungs
Disease control CompletedThis randomized controlled trial evaluated whether performing the same yoga-based breathing exercise program in a salt-cave environment produced different respiratory, functional, physical activity, and quality-of-life outcomes compared with the same program performed in a standa…
Sponsor: Sinop University • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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Music that adapts to you: new study tests brain and mood boost for seniors
Symptom relief OngoingThe proposed study is a pilot study that aims to understand if the Pi Electronics adaptive music intervention (AM) is effective to promote positive psychosocial and cognitive outcomes, over and above a traditional music intervention (TM) among healthy older adults. This study wil…
Sponsor: Toronto Metropolitan University • Aim: Symptom relief
Last updated Sep 06, 2026 00:00 UTC
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Free groceries or gift cards boost weight loss for those struggling with food access
Disease control CompletedThis study is a 3-group, parallel design, randomized controlled trial (RCT) in 105 adults with obesity and food insecurity that will compare BWL-Alone (including standard-of-care referral and connection with community food resources; n=35) to BWL plus food supplementation with ei…
Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Glucose monitor may help teens avoid diabetes
Disease control CompletedThe incidence of type 2 diabetes (T2D) in children is increasing, paralleling the rising incidence of obesity. Preventing children and adolescents from developing T2D is critical. The health benefits of lifestyle modifications are well documented in this population, but success r…
Sponsor: Nemours Children's Clinic • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Boosting progesterone may save IVF pregnancies
Disease control PausedEndometrin is a progesterone supplement prescribed during in vitro fertilization (IVF) for preparation for embryo transfer. The usual dose of Endometrin is 100 mg two to three times per day in the form of an effervescent tablet to be inserted vaginally. The purpose of this resea…
Phase 2 • Sponsor: Clinique Ovo • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Could a sleep aid curb opioid and stimulant use?
Symptom relief CompletedThis study will evaluate whether Suvorexant 20mg reduces drug use and craving, and improves sleep and stress among persons with co-occurring opioid use disorder and stimulant use disorder.
Phase 2 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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New training aims to help veterans with brain injury and PTSD read emotions
Symptom relief OngoingPoor emotion recognition has been associated with poor quality of interpersonal relationships, loss of employment, behavioral problems, reduced social reintegration, social isolation and even suicide. Deficits in emotion recognition are common in traumatic brain injury (TBI) and …
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jul 23, 2026 00:00 UTC
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Air filters may help lower lead levels in kids
Disease control Recruiting nowThe objective of this study is to assess the effectiveness of portable air filtration (PAF) for mitigating lead dust exposures and reducing childhood blood lead levels in older housing.
Sponsor: Michigan State University • Aim: Disease control
Last updated Jun 27, 2026 11:04 UTC
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Diabetes drug semaglutide may lower dementia risk, huge study suggests
Knowledge-focused CompletedThis study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the same indication.
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Gene testing aims to make cancer meds safer
Knowledge-focused Recruiting nowThe purpose of this study is to determine whether a consultation with a Personalized Therapeutics Clinic, or PTC, will help participants lower the risk for side effects (drug-drug interactions and drug-gene interactions) when taking many medications and help providers improve pre…
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Mindfulness may boost Self-Care in heart failure patients with cognitive decline
Symptom relief OngoingThis projects studies the role of mindfulness training (MT) to improve self-care among patients with heart failure and cognitive impairment.
Sponsor: The Miriam Hospital • Aim: Symptom relief
Last updated Aug 07, 2026 00:00 UTC
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Mind over pain: meditation studied as opioid alternative
Symptom relief Recruiting nowThe purpose of this research study is to see how a mindfulness meditation-based intervention affects pain. Specifically, we are interested in understanding the pain-relieving brain mechanisms of mindfulness meditation-based therapy for patients with opioid-treated chronic low bac…
Sponsor: University of Utah • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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New telehealth program aims to ease the burden on stroke caregivers
Symptom relief OngoingCaring for a family member after a stroke can be very difficult and worsen the physical and mental health of untrained caregivers. The TASK III intervention is a unique, comprehensive caregiver intervention program that enables caregivers to develop the necessary skills to manage…
Sponsor: University of Cincinnati • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Can digestive enzymes help pancreatic cancer patients keep weight on?
Disease control OngoingThe main purpose of this study is to see how pancrelipase affects the body mass index (BMI) in people with metastatic PDAC. BMI is a measure based on a person's height and weight. Other study goals are to explore two different dosing schedules of pancrelipase and to evaluate panc…
Phase 1/2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC