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127005 trials found · Page 2617 of 6351
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Robot trainer targets knee pain: new study tests Off-Axis training
Symptom relief Not yet recruitingAlthough the primary knee motion occurs in flexion/extension, the frontal and transverse (off-axis) knee motions are smaller but crucial for maintaining joint stability and normal knee loading. Altered kinematics and neuromuscular control in off-axis knee motions have been report…
Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Jul 30, 2026 00:00 UTC
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Can a simple suture tape make ACL surgery stronger?
Disease control Not yet recruitingThere is no consensus regarding the best surgical management of primary ACL tears. Recent evidence suggests that internal brace augmentation may increase load failure and therefore stabilize the graft in-situ at the time of ACL reconstruction. This prospective randomized controll…
Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Experimental vaccine aims to tame rare throat tumor disease
Disease control Recruiting nowThe purpose of this study is to evaluate the safety and immunogenicity of autologous DC vaccine in recurrent respiratory papillomatosis patients
Phase 1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Pre-Game huddle could be a Game-Changer for concussion safety in youth soccer
Prevention Not yet recruitingInvestigators will conduct a randomized controlled trial assessing the effectiveness and implementations of Pre-Game Safety Huddles (Huddles) in youth soccer.
Sponsor: Seattle Children's Hospital • Aim: Prevention
Last updated Jun 27, 2026 11:03 UTC
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New eye drop aims to ease pain of retinal shots
Symptom relief Not yet recruitingThis is a randomized, double-masked study to evaluate the tolerability and safety of IRX-101 versus 5% povidone-iodine (PI) in subjects receiving intravitreal anti-VEGF injections.
Phase 3 • Sponsor: iRenix Medical, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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AI spots heart clues in bone scans: a new way to catch a silent killer?
Diagnosis Not yet recruitingThis study aims to determine the positive predictive value of incidental cardiac uptake on bone scintigraphy for diagnosing transthyretin cardiac amyloidosis, in patients who underwent scintigraphy for reasons other than suspected amyloidosis. The study is an observational, descr…
Sponsor: University Hospital, Lille • Aim: Diagnosis
Last updated Jun 27, 2026 12:33 UTC
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Massage therapy could boost sperm quality in men with varicocele
Disease control Not yet recruitingThe project aims to evaluate the effects of a visceral osteopathic manual therapy (VOM) protocol on semen parameters and testicular hemodynamic indicators in men diagnosed with varicocele. Varicocele, the most common correctable cause of male infertility, is a progressive vascula…
Sponsor: Ankara Yildirim Beyazıt University • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Can a Light-Up mask turn back the clock on Sun-Damaged skin?
Symptom relief Not yet recruitingMain objective : To evaluate the anti-aging effectiveness of the LED mask alone on at least one studied anti-aging parameters (including some targeted wrinkles) after 3 months versus baseline Secondary objectives: * Anti-aging clinical score (radiance, skin tone, fine line, pto…
Sponsor: L'Oreal • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Can earplugs and quiet nights help ICU patients sleep better?
Symptom relief Not yet recruitingSleep disturbances are highly prevalent among patients admitted to intensive care units (ICUs). Critical illness, environmental factors, and routine clinical care frequently result in fragmented sleep, reduced sleep quality, and disruption of normal circadian rhythms. Previous st…
Sponsor: Fundación de investigación HM • Aim: Symptom relief
Last updated Jul 18, 2026 00:00 UTC
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Can talk therapy heal the wounds of Weight-Based bullying in kids?
Symptom relief Not yet recruitingThe goal of this feasibility study is to learn whether a trauma therapy intervention for children and adolescents who have experienced weight-based bullying can be successfully delivered within a pediatric weight management program. The intervention is informed by Trauma-Focused …
Sponsor: Western University • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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Enzyme injection could loosen stiff joints in brain and spinal cord injuries
Symptom relief Not yet recruitingThe overall goal is to investigate the effectiveness of a novel intervention - Collagenase injection, for contracture management in patients with neurological impairments, such as stroke, brain injury, and spinal cord injury.
Early phase 1 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Wearable sleep trackers reveal how Weight-Loss surgery changes rest
Knowledge-focused Not yet recruitingObesity is frequently associated with sleep disturbances, including poor sleep quality, insomnia symptoms, daytime sleepiness, and obstructive sleep apnea. Metabolic surgery is an effective treatment for obesity and may improve several sleep-related outcomes, but the long-term ch…
Sponsor: Catharina Ziekenhuis Eindhoven • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Enzyme injection could loosen stiff muscles in stroke survivors
Symptom relief Not yet recruitingThe overall goal is to investigate the effectiveness of a novel intervention - Collagenase injection, for spasticity management in patients with neurological impairments, such as stroke, brain injury, and spinal cord injury.
Early phase 1 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Scientists target GLUT1 to tame immune attacks in type 1 diabetes
Knowledge-focused Not yet recruitingType 1 Diabetes is an autoimmune disease in which immune cells contribute to the destruction of insulin-producing pancreatic beta cells. This study investigates whether targeting glucose transporter 1 (GLUT1), a transporter involved in immune cell metabolism, may help modulate au…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Guiding survivors: navigation program aims to boost access to supportive care
Symptom relief Recruiting nowThis clinical trial studies whether a navigation program improves survivorship support service participation among survivors of breast cancer that has not spread from where it first started (primary site) to other places in the body (non-metastatic). Advances in treatment have ca…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Aug 16, 2026 00:00 UTC
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Finger injections aim to loosen stiff hands in scleroderma
Symptom relief Not yet recruitingTranslational studies have demonstrated reduced hyaluronidase activity in the skin of patients with systemic sclerosis. It is thought this may contribute to the progressive fibrosis seen in this disease. Several studies have demonstrated that exogenous hyaluronidase is very effec…
Early phase 1 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jul 15, 2026 00:00 UTC
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Babywearing in the NICU: a new way to bond without using your arms
Symptom relief Not yet recruitingThe significance of skin-to-skin care (SSC) for neonatal infants is well-documented, highlighting its benefits for both the infant and the caregiver. The World Health Organization (WHO) has emphasized the necessity of positioning the infant on the mother after birth in a manner t…
Early phase 1 • Sponsor: University of Arizona • Aim: Symptom relief
Last updated Jul 22, 2026 00:00 UTC
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Stomach lining may hold clues to pancreatitis outcomes
Knowledge-focused Not yet recruitingThis is a prospective observational cohort study designed to evaluate early upper gastrointestinal endoscopic findings in adult patients hospitalized with acute pancreatitis. The study aims to determine whether gastric and duodenal mucosal abnormalities detected during early hosp…
Sponsor: Jan Kochanowski University • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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A scent of relief? lavender and sandalwood put to the test for Post-C-Section recovery
Symptom relief Not yet recruitingThe purpose of this randomized controlled study is to explore whether lavender sandalwood aromatherapy can support comfort, mood, pain relief, and overall satisfaction for participants recovering from a scheduled cesarean section without complications. The main questions this stu…
Sponsor: Memorial Hermann Health System • Aim: Symptom relief
Last updated Aug 14, 2026 00:00 UTC
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Could muscle size on MRI forecast how well you recover from back surgery?
Knowledge-focused Not yet recruitingRecovery after surgery for a herniated disc in the lower back differs from person to person. The size of the muscles around the lower spine may be related to recovery, but this relationship is not well understood. The purpose of this observational study is to determine whether t…
Sponsor: Fatih Sultan Mehmet Training and Research Hospital • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC