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116076 trials found · Page 2426 of 5804
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Can group support and home monitoring tame Post-Stroke blood pressure?
Disease control Recruiting nowThe investigators want to improve care for people who have had a stroke. High blood pressure is the leading cause for having a second stroke and can lead to poor brain health. The goal of this study is to compare two new ways of lowering blood pressure. The first way is to help p…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Could a cheap heart pill calm restless legs in dialysis patients?
Symptom relief Recruiting nowThe purpose of this clinical trial is to determine whether dipyridamole can treat restless legs syndrome in patients with uremia. In addition, the safety of dipyridamole will also be evaluated. The main questions this study aims to answer include: Can dipyridamole improve the sym…
Phase: PHASE2, PHASE3 • Sponsor: Yunfeng Xia • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Bone marrow injection shows promise for severe stroke
Disease control Not yet recruitingAn open-label, blinded Ib/IIa study investigating the treatment of acute large hemispheric infarction by transcranial bone marrow injection of RK-4 injection For subjects with acute large hemispheric infarction who are contraindicated to vascular recanalization or have poor resp…
Phase: PHASE1, PHASE2 • Sponsor: Neurodawn Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New combo therapy aims to ease fibromyalgia pain
Symptom relief Recruiting nowFibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters. The current mainstream treatments include pregabalin, but the efficac…
Phase: NA • Sponsor: Beijing Tiantan Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Gut feeling: probiotic shows promise for mood in stomach disorder
Symptom relief Recruiting nowObjective: This study aims to evaluate the effectiveness of Bacillus coagulans in improving anxiety and depression in patients diagnosed with functional dyspepsia according to the Rome IV criteria. Methods: This trial plans to enroll 180 patients (90 per group). The study will e…
Phase: PHASE4 • Sponsor: Xijing Hospital of Digestive Diseases • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Can weight training strengthen muscles in young CMT patients?
Symptom relief Recruiting nowThe goal of this clinical trial is to compare the effects of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals aged 15 to 29 years, with and without Hereditary Sensorimotor Polyneuropathy (HSPN…
Phase: NA • Sponsor: Universidad de La Frontera • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Gene test may predict who needs more immunotherapy after lung cancer surgery
Knowledge-focused Not yet recruitingThis multicenter, retrospective cohort study plans to enroll patients with lung adenocarcinoma who received neoadjuvant immunotherapy prior to surgery and did not achieve pathological complete response (non-pCR) upon postoperative pathological evaluation. Using Deoxyribonucleic A…
Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:30 UTC
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Blood markers may predict heart attack severity
Diagnosis Not yet recruitingTo assess the diagnostic and prognostic significance of MPV and SIRI in patients presenting with acute coronary syndrome.(STEMI/NSTEMI/UN STABLE ANGINA)
Sponsor: Assiut University • Aim: Diagnosis
Last updated Jun 26, 2026 12:52 UTC
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New painkiller may prevent sudden severe pain after shoulder surgery
Symptom relief CompletedShoulder arthroscopy is a frequently performed orthopedic procedure used to address various issues like rotator cuff tears, instability, and stiffness. However,postoperative pain is a common complaint, effective postoperative pain management is a crucial component to recovery aft…
Phase: PHASE4 • Sponsor: Liu Jiuhong • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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New pain shot could cut opioid use after back surgery
Symptom relief CompletedSpine surgery often causes severe postoperative pain. Currently, our hospital routinely uses ropivacaine for local infiltration analgesia (lasting 6-8 hours). This study evaluates liposomal bupivacaine, a novel long-acting local anesthetic providing up to 72 hours of pain relief,…
Phase: PHASE4 • Sponsor: Min Li • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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New absorbable nerve cap aims to stop phantom pain after finger loss
Disease control Recruiting nowIn 2016, one in five individuals in the United States (US) experienced chronic pain, and approximately 40% of them suffered from neuropathic pain. The physical and emotional burden on patients results in costs of billions of dollars annually. Digital amputations affect over 23,00…
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Can a smart food program plus glucose tracking transform diabetes care?
Disease control Recruiting nowThis study is designed to test the feasibility and preliminary efficacy of a continuous glucose monitor (CGM)-augmented food is medicine (FIM) intervention for adults with type 2 diabetes and nutrition or food insecurity. This study will learn if a FIM intervention ("intervention…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Can a supplement duo boost fertility in women with PCOS?
Disease control Recruiting nowThe goal of this clinical trial is to learn if combination of levocarnitine and myoinositol works better than myoinositol alone on insulin resistance and hormonal parameters in subfertile women with insulin resistant polycystic ovary syndrome . It will also learn about the safety…
Phase: NA • Sponsor: Mst.Sumyara Khatun • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Can we spot brain trouble early in CAR t-cell patients?
Knowledge-focused Recruiting nowThe goal of this study is to understand why some people receiving chimeric antigen receptor (CAR) T-cell therapy for cancer experience neurotoxicity. The main question it aims to answer is: Can a novel tool be developed to identify early the patients who will develop immune effe…
Sponsor: University of California, San Diego • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Brain-Training app aims to spark motivation in depressed seniors
Symptom relief Recruiting nowThe goal of this randomized controlled trial is to evaluate the potential of a customized digital cognitive training intervention to target aspects of brain function in apathy of late-life depression and reduce symptoms of apathy and related cognitive and behavioral deficits. The…
Phase: NA • Sponsor: AdventHealth • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New combo therapy for endometrial cancer tested in Real-World setting
Disease control Recruiting nowObjectives of this study are to assess the safety and effectiveness of Durvalumab with or without Olaparib (hereinafter "the study drug") in a real world setting in patients who are prescribed with the study drug under the approved indication in Korea. This is a multicenter, pro…
Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New drug enatumab tested for tough blood disorder
Disease control Not yet recruitingGlucocorticoids are the first-line treatment for wAIHA, but patients are prone to recurrence after dose reduction or discontinuation of glucocorticoids. Birgens et al. 's study found that approximately 55% of patients treated with prednisolone monotherapy experienced recurrence a…
Phase: PHASE2 • Sponsor: Bing Han • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New study aims to cut bleeding in fibroid surgery
Disease control Recruiting nowThis study hypothesizes that temporary bilateral uterine and utero-ovarian artery occlusion with laparoscopic clamps at time of minimally invasive myomectomy will lead to a decreased blood loss at time of myomectomy compared to minimally invasive myomectomy without temporary occl…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Can a VR seaside meditation lift depression that pills Can't?
Symptom relief Recruiting nowThe primary aim of this study is to evaluate the efficacy and tolerability of a combined Virtual Reality (VR)-based mindfulness intervention and pharmacological treatment compared with pharmacological treatment alone in reducing depressive symptoms in patients with Treatment-Resi…
Phase: NA • Sponsor: Hospital Universitari Vall d'Hebron Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Spinal zap plus robot arm training shows promise for hand movement
Symptom relief Recruiting nowThis study is aimed to evaluate whether transcutaneous spinal cord stimulation (tSCS) can augment upper limb robotic training (ULRT) to improve functional mobility in participants with chronic spinal cord injuries. It also evaluates the impact of the tSCS+ULRT on health-related q…
Phase: NA • Sponsor: National University Hospital, Singapore • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC