New heart stent tool could simplify procedures for millions

NCT ID NCT05437900

Recruiting now Disease control Sponsor: CoreAalst BV Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a new pressure microcatheter works as well as the standard pressure wire for guiding stent placement in people with coronary artery disease. About 2,500 participants will be randomly assigned to one of the two devices during their procedure. The main goal is to see if the microcatheter leads to similar rates of major heart problems like death, heart attack, or repeat procedures over one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pressure microcatheter (a thin tube used during heart stent placement to measure blood flow)
What this could lead to: If it works, this could show that the pressure microcatheter is just as good as the standard wire for guiding stent placement, potentially offering doctors a simpler tool.
What could go wrong: This is a large phase 4 trial, but it's testing non-inferiority (not superiority), so the new device may not be better. Risks include typical heart procedure complications like bleeding or vessel damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE CORONARY SYNDROME CORONARY ARTERY DISEASE

Contacts and locations

Locations

Amsterdam UMC
RECRUITING

Amsterdam, Netherlands
Azienda Ospedaliera Universitaria Federico II
RECRUITING

Naples, Italy
Azienda Ospedaliera Universitaria Sant'Andrea
RECRUITING

Rome, Italy
CHU Lille
RECRUITING

Lille, France
Catharina Ziekenhuis
RECRUITING

Eindhoven, Netherlands
Catholic Medical Center Koblenz-Montabaur
ACTIVE_NOT_RECRUITING

Koblenz, Germany
Claude Bernard University
ACTIVE_NOT_RECRUITING

Lyon, France
Dr. Jurasz University Hospital No. 1
RECRUITING

Bydgoszcz, Poland
Germans Trias i Pujol Hopital
RECRUITING

Barcelona, Spain
Herzzentrum Dresden
RECRUITING

Dresden, Germany
Herzzentrum Lahr
RECRUITING

Lahr, Germany
Hospital Clínic Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital de Belvitge
RECRUITING

Barcelona, Spain
ICPS
RECRUITING

Paris, France
John Paul II Specialistic Hospital
RECRUITING

Krakow, Poland
Klinikum Fürth
RECRUITING

Fürth, Germany
Klinikum Herford
RECRUITING

Herford, Germany
National Cardiac Institute
RECRUITING

Warsaw, Poland
Nuovo Arcispedale S.Anna Di Ferrara
RECRUITING

Ferrara, Italy
OLV Aalst
RECRUITING

Aalst, Oost-Vlaanderen, 9300, Belgium
Ospedale Civile Sant'Andrea
RECRUITING

La Spezia, Italy
Ospedale Santa Maria Goretti
RECRUITING

Latina, Italy
QILU Hospital of Shandong University
ACTIVE_NOT_RECRUITING

Shandong, China
UMCN Radboud
RECRUITING

Nijmegen, Netherlands
Universitair ziekenhuis Brussel
RECRUITING

Brussels, Belgium
Universitätsklinik
RECRUITING

Mainz, Germany
West China Hospital of Sichuan University
ACTIVE_NOT_RECRUITING

Sichuan, China
ZOL
RECRUITING

Genk, Belgium
Zhongshan Hospital of Fudan University
ACTIVE_NOT_RECRUITING

Shanghai, Xuhui District, 200031, China

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