New registry tracks stroke prevention without blood thinners

NCT ID NCT05565209

Recruiting now Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 250 atrial fibrillation patients who received a left atrial appendage closure device to prevent strokes. The procedure blocks a small pouch in the heart where clots often form, allowing patients to avoid long-term blood thinners. Researchers will track how many patients have strokes or other clots over five years to see how well the procedure works in the long run.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Left atrial appendage closure device
What this could lead to: If successful, this study could confirm that left atrial appendage closure is a safe and effective long-term alternative to blood thinners for preventing strokes in atrial fibrillation patients.
What could go wrong: This is an observational registry, not a controlled trial, so results may not prove cause and effect. Long-term data collection may have missing or incomplete records.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation Hemorrhage stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

Assistance Publique Hôpitaux de Paris - CHU HENRI MONDOR
RECRUITING

Créteil, 94010, France

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