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116076 trials found · Page 2106 of 5804
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Stent showdown: which Drug-Coated heart stent and blood thinner plan works best?
Disease control CompletedObjectives 1. To evaluate the safety and long-term effectiveness of coronary stenting with the Everolimus-eluting coronary stent system(EECSS) (XIENCETM V, Abbott Vascular, Santa Clara, CA, PromusTM, Boston Scientific, Natick, MA), compared with the sirolimus-eluting coronary st…
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Knee surgery or PT? landmark study compares treatments for torn meniscus with arthritis
Disease control CompletedThere are two cartilage structures, called menisci, in each knee joint. A torn meniscus can be caused by a traumatic injury or aging-related degeneration. Osteoarthritis (OA) is a type of arthritis that is caused by the breakdown and eventual loss of another type of cartilage tha…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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CT scan may spare kids from invasive scope for inhaled objects
Diagnosis CompletedTo access CT Scan as a diagnostic tool for foreign bodies aspiration.
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 27, 2026 08:11 UTC
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MIT's smart knee could make walking easier for amputees
Disease control OngoingThe purpose of the study is to investigate the clinical and functional outcomes of a powered knee prosthesis for people with a transfemoral amputation in the domain of gait, free space control, and embodiment
Phase: NA • Sponsor: Massachusetts Institute of Technology • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New monthly shot could simplify anemia treatment for kidney patients
Disease control CompletedThis 2 arm study will compare the efficacy and safety of monthly administration of subcutaneous Mircera versus epoetin alfa for the maintenance of hemoglobin levels in dialysis patients with chronic renal anemia. Patients currently receiving maintenance treatment with epoetin alf…
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 26, 2026 16:06 UTC
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Cystic fibrosis diabetes gene hunt: 1,500 patients sought
Knowledge-focused ENROLLING_BY_INVITATIONThis research is being done to find the genes and other factors that are responsible for differences among persons with cystic fibrosis. We are particularly interested in the factors that relate to the development of Cystic Fibrosis Related Diabetes (CFRD).
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Stent showdown: which Drug-Coated device keeps heart arteries open longer?
Disease control CompletedThe objective of this study is to evaluate the safety and long-term effectiveness of coronary stenting with the everolimus-eluting stent (EES) and to determine clinical device and procedural success during commercial use of EES in the real world. The investigators will compare E…
Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Can a different type of talk therapy help PTSD as well as standard treatments?
Symptom relief CompletedThis study will examine whether interpersonal psychotherapy is as effective in treating post-traumatic stress disorder as the established therapies of prolonged exposure and relaxation.
Phase: NA • Sponsor: New York State Psychiatric Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Could a stronger dose of risperidone help when standard treatment fails?
Disease control CompletedThe purpose of this study is to look at two doses of long-acting injectable risperidone (Risperdal Consta). The study will use a usual dose of Risperdal Consta (50 mg given every two weeks) or a higher dose (75 mg-100 mg given every two weeks) to see which one is better at improv…
Phase: PHASE4 • Sponsor: Northwestern University • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New combo therapy aims to stop head and neck cancer return
Disease control CompletedRATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Monoclonal antibodies, such as cetuxim…
Phase: PHASE2 • Sponsor: Centre Antoine Lacassagne • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Can your genes predict sudden cardiac arrest?
Knowledge-focused CompletedSudden death is a major problem in industrially developed countries. Despite a decline in ischemic heart disease mortality and the progress has been made in resuscitation, treatment of sudden death victims is frequently unsuccessful. the ideal solution would be to prevent the dis…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New drug MP-424 shows promise against hepatitis c in early trial
Disease control CompletedThe purpose of this study is to assess the efficacy and safety after administration of MP-424 to patients with chronic hepatitis C.
Phase: PHASE2 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Heart MRI study aims to spot who is at risk from myocarditis
Knowledge-focused ENROLLING_BY_INVITATIONMyocarditis and inflammatory cardiomyopathy represent a broad spectrum of myocardial inflammatory disorders with highly variable clinical presentations and outcomes, ranging from spontaneous recovery to progressive heart failure, malignant arrhythmias, and sudden cardiac death. D…
Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Sugar drinks during labor may cut need for forceps delivery
Symptom relief CompletedFear of full stomach when emergency general anaesthesia is required is the origin of fastening when giving birth. This behaviour does not warranty perfect security for the general anaesthesia. In addition, well being for women and new born is affected. Giving birth is finally com…
Phase: NA • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Gene study aims to uncover pancreatic cancer risks in ashkenazi jews
Knowledge-focused Recruiting nowThe aim of this study is to determine the frequency of the three most common BReast CAncer gene 1 (BRCA1) and BReast CAncer gene 2 (BRCA2) genetic mutations that are commonly found in Ashkenazi Jewish patients with pancreatic cancer. Testing for BRCA1 and BRCA2 mutations in relat…
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Smoking ban may shield Non-Smokers' blood vessels
Knowledge-focused CompletedEndothelium is considered a real member, so it is contributing to determine the vascular homeostasis. The presence of endothelial dysfunction, evaluated in peripheral arteries by non-invasive study of the variation of gauge of the brachial artery as a result of post-ischemic hype…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Can we predict the best RA drug? new study seeks answers
Knowledge-focused Recruiting nowRheumatoid arthritis (RA) is a common disease with approximately 1% prevalence. RA is also a chronic, progressive disease with no cure. Current treatment goals are to minimize pain, limit joint damage, and prevent loss of function. Drugs used to treat RA include non-steroidal ant…
Phase: PHASE3 • Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Blood markers may flag lung transplant danger — study investigates
Knowledge-focused Recruiting nowPrimary graft dysfunction (PGD) is a severe lung complication that can occur in the days after lung transplant surgery. This study will analyze blood samples to determine if high levels of certain chemicals may increase the risk of developing PGD after a lung transplant.
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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Can a single CT scan replace two tests for bladder cancer?
Diagnosis OngoingThe goal of this clinical research study is to use computed tomography urography (CTU) scans and intravenous urography (IVU) scans to check the status of urothelial cancer, in order to try to learn the level of effectiveness of possibly using CTU by itself in future patients.
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:07 UTC
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Could an existing drug treat sickle cell? researchers launch blood sample hunt
Knowledge-focused Recruiting nowThis study will collect representative blood samples from healthy children and adults and from children and adults who have unique red blood cell features that are related to sickle cell disease. Sickle cell disease is a blood disease that limits the ability of red blood cells to…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC