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127005 trials found · Page 1855 of 6351
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Can a team approach to rehab ease chronic back pain?
Symptom relief CompletedThe overall aim of this pilot RCT is to assess the feasibility of conducting a future definitive randomized control trial (RCT) for evaluating the effectiveness of an interprofessional rehabilitation program compared to the usual care in adults with chronic low back pain in Ethio…
Sponsor: Sintayehu Wami • Aim: Symptom relief
Last updated Sep 03, 2026 00:00 UTC
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Robot or human? new study compares arm therapy methods for stroke patients
Symptom relief CompletedThis study aims to compare the outcomes of upper limb motor therapy conducted by a physiotherapist with robot-assisted therapy using the Luna EMG device in patients in the subacute phase after stroke. Additionally, the study will examine the correlation between changes in muscle …
Sponsor: Wroclaw University of Health and Sport Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Mind-Body exercise may rewire how knees handle pain
Symptom relief CompletedThe goal of this clinical trial is to compare a pain informed movement program to standard neuromuscular exercise in people with knee osteoarthritis. The main question it aims to answer are: 1. Are the two interventions a) pain informed movement program plus pain neuroscience ed…
Sponsor: McMaster University • Aim: Symptom relief
Last updated Aug 30, 2026 00:00 UTC
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New psoriasis pill shows promise in early trial
Disease control CompletedThe purpose of this study is to evaluate clinical effectiveness and safety of BMS-986322 in participants with moderate-to-severe psoriasis.
Phase 2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Heat waves for bladder relief? radiofrequency shows promise for overactive bladder
Symptom relief CompletedA prospective, randomized, single-blind, placebo-controlled study was conducted from June 2023 to May 2025. The study enrolled 95 women (N=48 in the study group; N=47 in the placebo group) who presented with confirmed symptoms of OAB and UUI prior to enrollment. Symptom severity …
Sponsor: University Maribor • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Could a tiny dose of thyroid hormone heal fatty liver disease?
Disease control Recruiting nowNonalcoholic steatohepatitis (NASH) is the aggressive form of nonalcoholic fatty liver disease, which is rapidly becoming a worldwide public health problem. It is more common in the military and Veteran population compared to the general US population. NASH may progress to end-st…
Phase 2 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Gentle movement therapy may help preterm babies at risk of cerebral palsy
Disease control OngoingBackground: Very preterm babies are at high risk for developmental disorders. Prechtl's General Movements (GMs) Assessment is a valuable and reliable tool in infants until three months corrected age for predicting their further developmental difficulties, particularly cerebral pa…
Sponsor: University of Zurich • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Sham surgery showdown: is MALS release a real fix or just a myth?
Symptom relief Recruiting nowIn patients with Median Arcuate Ligament Syndrome (MALS), significant external compression of the coeliac artery (CA) by the median arcuate ligament (MAL) increasing mucosal ischemia (1,2) is assumed to cause chronic disabling postprandial abdominal pain, weight loss, and consequ…
Sponsor: Medisch Spectrum Twente • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Heart shunt shows promise for easing heart failure symptoms
Disease control OngoingThis is a prospective, multi-center, randomized, sham-controlled, double-blinded (participant and outcomes assessor) clinical trial.
Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Gut bacteria boost may curb obesity in rare genetic disorder
Disease control Recruiting nowPrader-Willi syndrome (PWS) is a rare genetic disease, with hyperappetite and severe obesity. At present, there is no effective drugs and interventions to help control the appetite of PWS patients. More and more evidence has shown that gut microbiota is closely related to obesity…
Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Could a common diabetes drug ease fibromyalgia pain?
Symptom relief Recruiting nowThe main purpose of the project is to evaluate the safety and efficacy of low dose metformin for improving symptoms associated with fibromyalgia syndrome (FMS) via modulating neuroinflammatory pathways. The investigators hypothesize that FMS patients in the low-dose metformin con…
Phase 2 • Sponsor: University of Utah • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Could a longer course of vaginal progesterone cut preterm births in IVF?
Prevention Recruiting nowTo investigate the incidence of preterm birth in IVF fresh embryo transplantation cycle patients after prolonged vaginal progesterone treatment
Phase 4 • Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University • Aim: Prevention
Last updated Jun 27, 2026 13:06 UTC
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Can a single tracer light up cancer's first stop? a trial puts a hybrid dye-and-radioactive marker to the test.
Diagnosis Completed99mTc-nanocolloid, the world wide used hybrid tracer for dynamic sentinel node biopsy, has recently been replaced with 99mTc-nanoscan. The hybrid form (ICG-99mTc-nanoscan) has not yet been validated, to show the similarity between the lymphatic drainage pattern between ICG-99mTc-…
Sponsor: The Netherlands Cancer Institute • Aim: Diagnosis
Last updated Jul 24, 2026 00:00 UTC
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Can muscle oxygen levels reveal Parkinson's exercise limits?
Knowledge-focused CompletedThe primary aim of this study is to compare maximum and functional exercise capacity and muscle oxygenation during exercise test in patients with Parkinson's disease. The secondary aim is to evaluate respiratory functions, respiratory muscle strength and endurance, peripheral mus…
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Can a mouth rinse reveal hidden HPV risks in HIV patients?
Knowledge-focused CompletedThe study will evaluate 300 people living with HIV that attend the Vivent Clinic for HIV care. We will characterize our population and include age, race/ethnicity, sex at birth, tobacco use, alcohol use, other comorbidities, HPV vaccination status, other HPV disease, and lab valu…
Sponsor: Vivent Health • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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New study seeks to uncover hidden causes of cardiac arrest
Knowledge-focused OngoingManagement of the reversible causes in cardiac arrest is fundamental for successful treatment of out-of-hospital cardiac arrests. Point-of-care diagnostics as prehospital emergency ultrasound, blood gas analysis and toxicological screening support the diagnostic process of evalua…
Sponsor: Medical University of Vienna • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Can a new appliance rival the face mask for jaw correction?
Disease control CompletedRandomised clinical trial on 30 class lll patients on two groups each group consist of 15 patient to compare between Face mask and Ertty Appliance in Treatment of skeletal class lll Deficient maxilla.acone beam ct to every patient before and after treatment and a3D ceph traced to…
Sponsor: Minia University • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Sound waves zap kidney stones: no needle, no knife needed
Disease control Recruiting nowThis is a prospective, open-label, multi-center study to test the clinical feasibility of facilitating stone passage by the combination of breaking and repositioning stones with ultrasound, without the need for anesthesia.
Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Could your own tumor cells fight cancer? new trial tests TIL therapy
Disease control Recruiting nowThis study is to investigate the safety and efficacy of tumor infiltrating lymphocyte (TIL) therapy in patients with advanced solid tumors. Autologous TILs and gene-edited TILs are expanded from tumor resections or biopsies and infused i.v. into the patient after NMA lymphodeplet…
Early phase 1 • Sponsor: Shanghai Juncell Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Light on the forehead: a new hope for depression?
Symptom relief Recruiting nowThe purpose of this research study is to determine if application of near infrared energy to the forehead can change blood flow in the brains of people with depression. Near infrared energy is like light but is not visible to the human eye.
Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC