Could a common diabetes drug ease fibromyalgia pain?
NCT ID NCT05900466
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether low-dose metformin, a common diabetes drug, can improve symptoms of fibromyalgia by reducing inflammation in the nervous system. 72 adults with fibromyalgia will take metformin or a placebo daily for 8 weeks. Researchers will measure changes in pain, fatigue, and overall impact on daily life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Metformin (low-dose extended-release tablets)
- What this could lead to
- If it works, this could point toward a new, affordable treatment option for fibromyalgia symptoms.
- What could go wrong
- This is a small, early-stage proof-of-concept trial. Metformin is not proven for fibromyalgia yet, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Utah
RECRUITINGSalt Lake City, Utah, 84132, United States
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