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127005 trials found · Page 1790 of 6351
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Electric needles may offer new hope for bladder emptying problems
Disease control CompletedTo observe the clinical effects and make a comparative study between efficacy of electrical pudendal nerve stimulation (EPNS) and sacral neuromodulation (SNM) , evaluate the advantages of EPNS in the treatment of neurogenic non-obstructive urinary retention, and provide a new met…
Sponsor: Shanghai Institute of Acupuncture, Moxibustion and Meridian • Aim: Disease control
Last updated Jun 26, 2026 17:53 UTC
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Glow-in-the-dark tech may save parathyroid glands during thyroid cancer surgery
Disease control Recruiting nowThe study aims to test if use of autofluorescence imaging (AF) reduces the risk of developing hypoparathyroidism (hypoPT) following surgery for thyroid cancer, either total thyroidectomy (TT) or completion hemithyroidectomy (cHT).
Sponsor: Aarhus University Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Could adding a common antibiotic beat syphilis in HIV patients?
Disease control Recruiting nowThis randomized controlled superiority study will be conducted during 2023-2025. The eligible participants are adult people living with HIV (PLWH) who are newly diagnosed with early syphilis. Participants will be randomized in a 1:1 ratio to receive single-dose benzathine penicil…
Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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New study tests online therapy and exercise for long COVID fatigue
Symptom relief CompletedPost-Covid(PoC)-patients with fatigue symptoms respond very differently to physical rehabilitation programs. While PoC-patients with psychological symptoms benefit little from physical interventions, fatigue and exercise capacity improves significantly without the presence of psy…
Sponsor: Hannover Medical School • Aim: Symptom relief
Last updated Aug 19, 2026 00:00 UTC
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AI and blood tests aim to predict brain damage before it happens
Diagnosis Recruiting nowThe overall goal of this project is to determine if machine learning and analysis of neurospecific biomarkers can enable early detection of upcoming or ongoing cerebral ischaemia in patients suffering from subarachnoid haemorrhage with altered consciousness due to cerebral injury…
Sponsor: Sahlgrenska University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 08:10 UTC
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Head-to-Head: which drug works better for psoriatic arthritis in the real world?
Disease control CompletedPsoriatic arthritis (PsA) is a chronic inflammatory disease with heterogeneous musculoskeletal and dermatologic manifestations, leading to significant functional impairment and reduced quality of life. Although targeted therapies such as Janus kinase inhibitors and interleukin-17…
Sponsor: Peking University First Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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New combo pill could ease opioid withdrawal for outpatients
Symptom relief Recruiting nowA placebo-controlled trial in which male and female outpatients with an opioid use disorder who express interest in extended-release injectable naltrexone (XR-NTX) are randomized 1:1 to lofexidine/pregabalin or lofexidine/pregabalin placebo for withdrawal management and offered X…
Phase 2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Home workouts could help black men fight prostate cancer without surgery
Disease control Recruiting nowThe purpose of this study is to determine whether a 12-week, home-based, virtually supervised exercise program will slow cancer progression of prostate cancer among men with prostate cancer at high-risk of progression undergoing active surveillance. The name of the study interve…
Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Simple blood test may spot preeclampsia risk before symptoms appear
Diagnosis CompletedPreeclampsia is a pregnancy-specific hypertensive disorder that remains one of the leading causes of maternal and perinatal morbidity and mortality worldwide. Despite extensive research, reliable biomarkers for the early prediction of preeclampsia are still limited. Early identif…
Sponsor: Samsun University • Aim: Diagnosis
Last updated Jun 27, 2026 11:01 UTC
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New gel could halt tooth decay in preschoolers without drilling
Disease control OngoingThe objective is to determine whether the efficacy of a 38% silver diamine fluoride (SDF) gel is non-inferior to a 38% SDF solution for arresting carious lesions in preschool children when applied at half-yearly intervals over a 30-month period.
Phase 2 • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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New hope for tough lymphoma: glofitamab trial launches in china
Disease control Recruiting nowThis study will evaluate the safety and efficacy of glofitamab as a single agent in Chinese patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have failed two or more lines of systemic therapy.
Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Can a mesh wrap keep heart bypass grafts open longer?
Disease control By invitation onlyThe aim of the thesis is to compare a group of patients using vein grafts with and without external support, specifically their patency. This is a prospective study with a follow-up plan of 150 patients, in whom the functionality of the grafts will be monitored at time intervals.
Sponsor: University Hospital Pilsen • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Group therapy with parents may boost social skills in autistic preschoolers
Disease control CompletedThis is a study that investigate the feasibility, acceptability, and preliminary efficacy of NDBIs for autistic preschoolers delivered in a group-setting. The outcome measures assess the improvements in autistic symptoms, social communication, play skills, group behaviors, adapta…
Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Breathing easy: dynamic x-rays may spot COPD faster and safer
Diagnosis Recruiting nowThe prevalence of chronic obstructive pulmonary disease (COPD) is on the rise, leading to an increasing economic and social burden. Currently, the diagnosis and staging of COPD heavily rely on pulmonary function testing. However, limitations such as patient cooperation and comorb…
Sponsor: Nanfang Hospital, Southern Medical University • Aim: Diagnosis
Last updated Jul 22, 2026 00:00 UTC
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Stomach bug clues: can infection patterns forecast early cancer behavior?
Knowledge-focused Recruiting nowThis multicenter retrospective and prospective real-world observational study will evaluate the relationship of Helicobacter pylori (H. pylori) infection status, intragastric distribution, and pathological features with gastric cancer biological behavior and long-term prognosis i…
Sponsor: Chinese PLA General Hospital • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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A pocket-sized coach for insulin users? app aims to boost self-care in type 2 diabetes
Disease control CompletedThe main purpose of the research is; To develop a mobile application for individuals with Type 2 diabetes who use insulin and to examine the effect of the developed mobile application on the perception and self-management of insulin use.
Sponsor: Ege University • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Can acne drug harm the eyes? new study investigates
Knowledge-focused CompletedThe aim of the study was to evaluate meibomian gland morphology using non-contact meibography and ocular surface changes in patients with acne vulgaris treated with isotretinoin as indicators of dry eye, which is known to be a side effect of isotretinoin.
Sponsor: Benha University • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC
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Can gum disease be stopped by targeting these genes?
Knowledge-focused CompletedGum disease, including gingivitis and its more advanced form, periodontitis, is a common condition that damages the tissues supporting the teeth. This study examines how gum disease affects the expression of specific genes and proteins that regulate communication between internal…
Sponsor: Inonu University • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Can surgery pain be managed without opioids?
Disease control CompletedProspactive observational Clinical study
Sponsor: Democritus University of Thrace • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Can 3D-Printed braces reshape a Teen's smile as well as traditional ones?
Disease control Completed: To evaluate the effectiveness of functional device treatment using both 3D-printed and conventional Twin Block appliances on soft tissue changes during growth modification in Class II malocclusion.
Phase 1 • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC