Two-Drug combo shows promise against tough cancers
NCT ID NCT04007744
First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 29 times
Summary
This early-phase trial tests a new combination of two drugs—sonidegib and pembrolizumab—in 36 adults with advanced solid tumors that have spread. The goal is to find the safest dose and see if the combination can shrink tumors. Sonidegib blocks certain enzymes that help cancer grow, while pembrolizumab boosts the immune system to attack cancer cells.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
Conditions
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