LOCALLY ADVANCED UROTHELIAL CARCINOMA
Clinical trials for LOCALLY ADVANCED UROTHELIAL CARCINOMA explained in plain language.
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New combo aims to outsmart resistant bladder cancer
Disease control Recruiting nowThis study tests whether a combination of two drugs (pembrolizumab and sacituzumab govitecan) works better than standard chemotherapy for advanced bladder cancer that no longer responds to immunotherapy. About 320 adults with locally advanced or metastatic urothelial cancer will …
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 03:34 UTC
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Immune cell attack: new hope for tough bladder cancer?
Disease control Recruiting nowThis study tests a new treatment for people with advanced bladder cancer that has not responded to standard therapies. The treatment uses specially engineered immune cells (CAR-NK cells) from a healthy donor to target and kill cancer cells. Up to 42 adults will receive the cells …
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: Beijing Biotech • Aim: Disease control
Last updated May 26, 2026 03:30 UTC
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New drug cocktail shows promise for tough bladder cancer
Disease control Recruiting nowThis early-phase study tests a combination of two drugs—cabozantinib and enfortumab vedotin—in people with advanced bladder cancer that has spread or cannot be removed. The goal is to find the best dose and see if the combo is safe and shrinks tumors. About 32 adults who have alr…
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated May 26, 2026 02:48 UTC
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Can surgery lock in gains against advanced bladder cancer?
Disease control Recruiting nowThis study looks at whether adding surgery after drug treatment helps keep advanced bladder cancer from growing. About 32 people whose cancer is under control with medication will have surgery to remove remaining tumors. The goal is to see if this approach extends the time withou…
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated May 26, 2026 02:48 UTC
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Custom-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors (like breast, lung, or skin cancer). The goal is to see if the combination is safe and helps the immune syst…
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Cancer patients may soon get infusions at home, cutting travel and stress
Symptom relief Recruiting nowThis study tests whether giving the cancer drug nivolumab as a shot at home is as safe and effective as getting it in a clinic. About 50 adults with various cancers will try both settings to see which they prefer and how it affects their quality of life. The goal is to reduce the…
Matched conditions: LOCALLY ADVANCED UROTHELIAL CARCINOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 26, 2026 03:34 UTC